Is the MCM2-7 complex the eukaryotic DNA replication fork helicase? (Q34132841)

31 July 2017

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title

Is the MCM2-7 complex the eukaryotic DNA replication fork helicase? (English)

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John Francis Xavier Diffley

31 July 2017

series ordinal

2

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31 July 2017

Labib K

1

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31 July 2017

1 February 2001

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Current Opinion in Genetics & Development

31 July 2017

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31 July 2017

11

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31 July 2017

64-70

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31 July 2017

1

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Animal virus DNA replication

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Structure and function of simian virus 40 large tumor antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Systematic identification, classification, and characterization of the open reading frames which encode novel helicase-related proteins in Saccharomyces cerevisiae by gene disruption and Northern analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

MCM proteins: evolution, properties, and role in DNA replication.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

MCM proteins in DNA replication

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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

ATPase switches controlling DNA replication initiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

AAA proteins. Lords of the ring

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Subcellular localization of yeast CDC46 varies with the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

A yeast gene required for DNA replication encodes a protein with homology to DNA helicases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

DNA2 encodes a DNA helicase essential for replication of eukaryotic chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Dna2 of Saccharomyces cerevisiae possesses a single-stranded DNA-specific endonuclease activity that is able to act on double-stranded DNA in the presence of ATP.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

The nuclease activity of the yeast DNA2 protein, which is related to the RecB-like nucleases, is essential in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

The endonuclease activity of the yeast Dna2 enzyme is essential in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Identification of the Xenopus laevis homolog of Saccharomyces cerevisiae DNA2 and its role in DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Replication focus-forming activity 1 and the Werner syndrome gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Identification of nuclear pre-replication centers poised for DNA synthesis in Xenopus egg extracts: immunolocalization study of replication protein A

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Requirement of yeast SGS1 and SRS2 genes for replication and transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Binding specificity determines polarity of DNA unwinding by the Sgs1 protein of S. cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

The Bloom's syndrome gene product promotes branch migration of holliday junctions

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Possible association of BLM in decreasing DNA double strand breaks during DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Pif1p helicase, a catalytic inhibitor of telomerase in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

The Cdt1 protein is required to license DNA for replication in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis

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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Initiation of Eukaryotic DNA Replication

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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Electron microscopic observation and single-stranded DNA binding activity of the Mcm4,6,7 complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Biochemical function of mouse minichromosome maintenance 2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

The single minichromosome maintenance protein of Methanobacterium thermoautotrophicum DeltaH contains DNA helicase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

The intrinsic DNA helicase activity of Methanobacterium thermoautotrophicum delta H minichromosome maintenance protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Uninterrupted MCM2-7 function required for DNA replication fork progression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Cdc18 transcription and proteolysis couple S phase to passage through mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Negative regulation of Cdc18 DNA replication protein by Cdc2.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

A human protein related to yeast Cdc6p

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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

Mitotic replication initiation proteins are not required for pre-meiotic S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900158-1

7 January 2021

10.1016/S0959-437X(00)00158-1

Identifiers

DOI

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31 July 2017

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PubMed ID

11163153