Human Vav1 expression in hematopoietic and cancer cell lines is regulated by c-Myb and by CpG methylation (Q34130817)

31 July 2017

Human Vav1 expression in hematopoietic and cancer cell lines is regulated by c-Myb and by CpG methylation (English)

1 reference

31 July 2017

Lena Ilan

1

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author name string

Shulamit Katzav

series ordinal

2

1 reference

PubMed ID

22253833

31 July 2017

language of work or name

English

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publication date

11 January 2012

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31 July 2017

1 reference

31 July 2017

7

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31 July 2017

1

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31 July 2017

e29939

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Creative Commons Attribution 4.0 International

31 July 2017

start time

11 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity

5 July 2018

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Critical roles for c-Myb in lymphoid priming and early B-cell development

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Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck

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5 July 2018

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Vav1 and PU.1 are recruited to the CD11b promoter in APL-derived promyelocytes: role of Vav1 in modulating PU.1-containing complexes during ATRA-induced differentiation.

5 July 2018

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The haematopoietic specific signal transducer Vav1 is aberrantly expressed in lung cancer and plays a role in tumourigenesis

5 July 2018

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PU.1 and partners: regulation of haematopoietic stem cell fate in normal and malignant haematopoiesis

5 July 2018

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MYB function in normal and cancer cells

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Flesh and blood: the story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies

5 July 2018

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c-Myb is required for progenitor cell homeostasis in colonic crypts.

5 July 2018

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Osteopontin is an oncogenic Vav1- but not wild-type Vav1-responsive gene: implications for fibroblast transformation

5 July 2018

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The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of beta-like globin genes

5 July 2018

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Vav-family proteins in T-cell signalling

5 July 2018

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Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis

5 July 2018

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Vav-promoter regulated oncogenic fusion protein NPM-ALK in transgenic mice causes B-cell lymphomas with hyperactive Jun kinase

5 July 2018

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The haematopoietic specific signal transducer Vav1 is expressed in a subset of human neuroblastomas

5 July 2018

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PU.1 regulates the expression of the vav proto-oncogene

5 July 2018

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c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings

5 July 2018

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Regulatory and signaling properties of the Vav family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256210

Transcriptional regulation of vav, a gene expressed throughout the hematopoietic compartment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256210

Expression of the vav oncogene in somatic cell hybrids

5 July 2018

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Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

5 July 2018

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Vav cooperates with Ras to transform rodent fibroblasts but is not a Ras GDP/GTP exchange factor

5 July 2018

1 reference

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Expression of tal-1 and GATA-binding proteins during human hematopoiesis

5 July 2018

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Vav and Ras induce fibroblast transformation by overlapping signaling pathways which require c-Myc function

5 July 2018

1 reference

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Growth of cell lines and clinical specimens of human non-small cell lung cancer in a serum-free defined medium.

5 July 2018

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CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

5 July 2018

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vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells

5 July 2018

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The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

5 July 2018

1 reference

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Mechanism of activation of the vav protooncogene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256210

Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256210

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256210

AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029939

Regulatory elements of the vav gene drive transgene expression in hematopoietic stem cells from adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029939

c-Myb and p300 regulate hematopoietic stem cell proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029939

Collagen loss and impaired wound healing is associated with c-Myb deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029939

Deletion of genes encoding PU.1 and Spi-B in B cells impairs differentiation and induces pre-B cell acute lymphoblastic leukemia.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256210

Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256210

Developmental expression of the vav protooncogene.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256210

c-Myb Is Required for Neural Progenitor Cell Proliferation and Maintenance of the Neural Stem Cell Niche in Adult Brain

28 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029939

Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment

21 January 2018

1 reference

12 December 2020

Tissue-specific demethylation in CpG-poor promoters during cellular differentiation

1 reference

12 December 2020

Characterization of a human macrophage-like cell line stimulated in vitro: a model of macrophage functions

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12 December 2020

The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0029939

Identifiers

DOI

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference

PubMed ID

22253833