The contribution of reactive oxygen species and p38 mitogen-activated protein kinase to myofilament oxidation and progression of heart failure in rabbits. (Q34124823)

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English	The contribution of reactive oxygen species and p38 mitogen-activated protein kinase to myofilament oxidation and progression of heart failure in rabbits.	scientific article

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6 February 2020

The contribution of reactive oxygen species and p38 mitogen-activated protein kinase to myofilament oxidation and progression of heart failure in rabbits (English)

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6 February 2020

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reactive oxygen species

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6 February 2020

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P Heusch

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6 February 2020

M Canton

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S Aker

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A van de Sand

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I Konietzka

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T Rassaf

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S Menazza

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O E Brodde

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F Di Lisa

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G Heusch

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1 July 2010

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British Journal of Pharmacology

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1408-1416

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6

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6 February 2020

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Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms

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5 July 2018

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

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5 July 2018

G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure

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5 July 2018

Cardiac contractility modulation electrical signals improve myocardial gene expression in patients with heart failure

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5 July 2018

Apoptosis signal-regulating kinase 1/p38 signaling pathway negatively regulates physiological hypertrophy

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Mitogen-activated protein kinases in heart development and diseases

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5 July 2018

Potential of p38-MAPK inhibitors in the treatment of ischaemic heart disease

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5 July 2018

Hydrogen peroxide impairs GRK2 translation via a calpain-dependent and cdk1-mediated pathway

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5 July 2018

Inhibition of Na+/H+-exchanger with sabiporide attenuates the downregulation and uncoupling of the myocardial beta-adrenoceptor system in failing rabbit hearts.

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5 July 2018

Reactive oxygen species in cardiac signalling: from mitochondria to plasma membrane ion channels.

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5 July 2018

Role of p38alpha MAPK in cardiac apoptosis and remodeling after myocardial infarction

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5 July 2018

Oxygen, oxidative stress, hypoxia, and heart failure

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5 July 2018

STRESS signaling pathways that modulate cardiac myocyte apoptosis

1 reference

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5 July 2018

Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling

1 reference

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5 July 2018

p38 Mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938812

5 July 2018

Mitogen-activated protein kinases in the heart

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5 July 2018

Physiological consequences of tropomyosin mutations associated with cardiac and skeletal myopathies

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Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

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5 July 2018

Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits

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21 January 2018

Guide to Receptors and Channels (GRAC), 3rd edition

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21 January 2018

Antioxidants but not doxycycline treatments restore depressed beta-adrenergic responses of the heart in diabetic rats.

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21 January 2018

A Mutant Tropomyosin That Causes Hypertrophic Cardiomyopathy Is Expressed In Vivo and Associated With an Increased Calcium Sensitivity

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21 January 2018

Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts

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21 January 2018

Oxidative modification of tropomyosin and myocardial dysfunction following coronary microembolization

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21 January 2018

Activation of NADPH oxidase during progression of cardiac hypertrophy to failure

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21 January 2018

Antioxidants attenuate myocyte apoptosis and improve cardiac function in CHF: association with changes in MAPK pathways

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21 January 2018

Progressive left ventricular remodeling, myocyte apoptosis, and protein signaling cascades after myocardial infarction in rabbits

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21 January 2018

Identification of cell cycle regulatory and inflammatory genes as predominant targets of p38 mitogen-activated protein kinase in the heart.

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21 January 2018

Antioxidative effect of p38 mitogen-activated protein kinase inhibitor in the kidney of hypertensive rat.

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21 January 2018

Vascular endothelial dysfunction and superoxide anion production in heart failure are p38 MAP kinase-dependent

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21 January 2018

Differential Activation of Signal Transduction Pathways in Human Hearts With Hypertrophy Versus Advanced Heart Failure

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21 January 2018

p38-MAPK Induced Dephosphorylation of α-Tropomyosin Is Associated With Depression of Myocardial Sarcomeric Tension and ATPase Activity

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21 January 2018

Structure of co-crystals of tropomyosin and troponin

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21 January 2018

The amino acid sequence of rabbit cardiac tropomyosin

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12 December 2020

based on heuristic

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p38 mitogen activated protein kinase mediates both death signaling and functional depression in the heart

1 reference

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12 December 2020

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Functional significance of myofilament protein oxidationThe opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 mitogen-activated protein kinase: a future target for heart failure therapy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of p38 MAP kinase in not only activation of the phagocyte NADPH oxidase induced by formyl-methionyl-leucyl-phenylalanine but also determination of the extent of the activity

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of p38 MAPK Inhibitor on angiotensin II-dependent hypertension, organ damage, and superoxide anion production

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmented protein kinase C-alpha-induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 MAP kinase is a mediator of ischemic preconditioning in pigs

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress kinase phosphorylation is increased in pacing-induced heart failure in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced calcium responsiveness characterizes contractile dysfunction following coronary microembolization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2010.00793.X

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6 February 2020

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Europe PubMed Central

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6 February 2020

1 reference

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6 February 2020

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