Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina. (Q34124455)

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English	Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.	scientific article

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17 January 2020

Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina (English)

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17 January 2020

photoreceptor protein

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Rachael A. Pearson

1

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17 January 2020

Robert MacLaren

4

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17 January 2020

ORCID Public Data File 2021

James W. Bainbridge

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17 January 2020

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17 January 2020

author name string

A C Barber

2

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17 January 2020

E L West

3

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17 January 2020

Y Duran

5

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17 January 2020

R R Ali

8

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17 January 2020

publication date

20 January 2010

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17 January 2020

Cell Transplantation

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17 January 2020

19

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17 January 2020

4

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17 January 2020

487-503

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17 January 2020

Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in Crx-deficient mice

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Toll-like receptor 3 and geographic atrophy in age-related macular degeneration

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Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice.

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alpha-Aminoadipate induces progenitor cell properties of Müller glia in adult mice.

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5 July 2018

Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors

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Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium

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The role of Rds in outer segment morphogenesis and human retinal disease

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5 July 2018

Retinal repair by transplantation of photoreceptor precursors

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Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells

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Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA

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Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors

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Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure

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5 July 2018

CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina

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5 July 2018

Differentiation and morphological integration of neural progenitor cells transplanted into the developing mammalian eye.

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Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

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Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain

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Nrl is required for rod photoreceptor development

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Multiple phosphorylated isoforms of NRL are expressed in rod photoreceptors

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The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton

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12 December 2020

based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20089206

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based on heuristic

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Electron microscopic study of the development of retinal Müllerian cells

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https://pubmed.ncbi.nlm.nih.gov/20089206

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1 reference

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Identifiers

10.3727/096368909X486057

1 reference

Europe PubMed Central

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17 January 2020

1 reference

Europe PubMed Central

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17 January 2020

1 reference

Europe PubMed Central

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17 January 2020

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