Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. (Q34117556)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25083987%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

title

Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia (English)

1 reference

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11 March 2020

1 reference

4

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11 March 2020

author name string

David H Wang

1

1 reference

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11 March 2020

Anjana Tiwari

2

1 reference

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11 March 2020

Monica E Kim

3

1 reference

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11 March 2020

Nanda L Regmi

5

1 reference

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11 March 2020

William A Hodges

6

1 reference

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11 March 2020

David M Berman

7

1 reference

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11 March 2020

Elizabeth A Montgomery

8

1 reference

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11 March 2020

D Neil Watkins

9

1 reference

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11 March 2020

Xi Zhang

10

1 reference

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11 March 2020

Qiuyang Zhang

11

1 reference

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11 March 2020

Chunfa Jie

12

1 reference

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11 March 2020

Stuart J Spechler

13

1 reference

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11 March 2020

Rhonda F Souza

14

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11 March 2020

language of work or name

English

0 references

publication date

1 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25083987%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

11 March 2020

published in

1 reference

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11 March 2020

volume

124

1 reference

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11 March 2020

page(s)

3767-3780

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11 March 2020

issue

9

1 reference

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Barrett esophagus and risk of esophageal cancer: a clinical review

11 March 2020

cites work

1 reference

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Notch signaling pathway and Cdx2 expression in the development of Barrett's esophagus

5 July 2018

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Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.

5 July 2018

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Molecular mechanisms of Barrett's esophagus

5 July 2018

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Study of FoxA pioneer factor at silent genes reveals Rfx-repressed enhancer at Cdx2 and a potential indicator of esophageal adenocarcinoma development

5 July 2018

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Residual embryonic cells as precursors of a Barrett's-like metaplasia.

5 July 2018

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American Gastroenterological Association technical review on the management of Barrett's esophagus

5 July 2018

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BMP signaling in the development of the mouse esophagus and forestomach

5 July 2018

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Acid and bile salt-induced CDX2 expression differs in esophageal squamous cells from patients with and without Barrett's esophagus

5 July 2018

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Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia

5 July 2018

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Conversion of metaplastic Barrett's epithelium into post-mitotic goblet cells by gamma-secretase inhibition

5 July 2018

1 reference

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Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice

5 July 2018

1 reference

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Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation

5 July 2018

1 reference

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SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

5 July 2018

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Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice

5 July 2018

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SOX2 is highly expressed in squamous cell carcinomas of the gastrointestinal tract

5 July 2018

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Transdifferentiation, metaplasia and tissue regeneration.

5 July 2018

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Differential gene expression in normal esophagus and Barrett's esophagus

5 July 2018

1 reference

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Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.

5 July 2018

1 reference

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Intestinal differentiation in metaplastic, nongoblet columnar epithelium in the esophagus

5 July 2018

1 reference

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The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

5 July 2018

1 reference

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Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1

5 July 2018

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Differences in activity and phosphorylation of MAPK enzymes in esophageal squamous cells of GERD patients with and without Barrett's esophagus

5 July 2018

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Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line

5 July 2018

1 reference

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Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma

5 July 2018

1 reference

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Multilayered epithelium in a rat model and human Barrett's esophagus: similar expression patterns of transcription factors and differentiation markers

5 July 2018

1 reference

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Sox9 coordinates a transcriptional network in pancreatic progenitor cells

5 July 2018

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Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm

5 July 2018

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Characterization of telomerase-immortalized, non-neoplastic, human Barrett's cell line (BAR-T).

5 July 2018

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Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma

5 July 2018

1 reference

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Homozygous inactivation of Sox9 causes complete XY sex reversal in mice

5 July 2018

1 reference

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Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus.

5 July 2018

1 reference

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CDX1 is an important molecular mediator of Barrett's metaplasia

5 July 2018

1 reference

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Characterization of a novel Foxa (hepatocyte nuclear factor-3) site in the glucagon promoter that is conserved between rodents and humans

5 July 2018

1 reference

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Differences in ERK activation in squamous mucosa in patients who have gastroesophageal reflux disease with and without Barrett's esophagus

5 July 2018

1 reference

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Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis

5 July 2018

1 reference

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Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues

5 July 2018

1 reference

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Tissue repair and stem cell renewal in carcinogenesis

5 July 2018

1 reference

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Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

5 July 2018

1 reference

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SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

5 July 2018

1 reference

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Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium

5 July 2018

1 reference

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The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage

5 July 2018

1 reference

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Is intestinal metaplasia of the stomach reversible?

5 July 2018

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The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

5 July 2018

1 reference

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How cells change their phenotype

5 July 2018

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Requirement of Math1 for secretory cell lineage commitment in the mouse intestine

5 July 2018

1 reference

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Expression of p53-related protein p63 in the gastrointestinal tract and in esophageal metaplastic and neoplastic disorders

5 July 2018

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On differential variability of expression ratios: improving statistical inference about gene expression changes from microarray data

5 July 2018

1 reference

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

5 July 2018

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p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

5 July 2018

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Generalized lacZ expression with the ROSA26 Cre reporter strain

5 July 2018

1 reference

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Sonic hedgehog is essential to foregut development

5 July 2018

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Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus

5 July 2018

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A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

5 July 2018

1 reference

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

5 July 2018

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HNF-3 beta is essential for node and notochord formation in mouse development

5 July 2018

1 reference

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The histologic spectrum of Barrett's esophagus

5 July 2018

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Esophageal adenocarcinoma incidence: are we reaching the peak?

5 July 2018

1 reference

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Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells.

28 October 2018

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Expression of CDX2 and MUC2 in Barrett's mucosa.

28 October 2018

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The burden of selected digestive diseases in the United States.

28 October 2018

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The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis.

28 October 2018

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Aberrant expression of CDX2 in Barrett's epithelium and inflammatory esophageal mucosa

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25083987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Changes in bronchial epithelium in relation to cigarette smoking and in relation to lung cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25083987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI66603

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25083987%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25083987%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

1 reference