A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain (Q34111636)

31 July 2017

A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain (English)

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positron emission tomography

31 July 2017

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William E Klunk

11

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Bradley Hyman

6

object named as

Bradley T Hyman

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31 July 2017

5

Matthew P Frosch

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31 July 2017

Chester A Mathis

1

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31 July 2017

Brian J Bacskai

2

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31 July 2017

Stephen T Kajdasz

3

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31 July 2017

Megan E McLellan

4

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31 July 2017

Daniel P Holt

7

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31 July 2017

Yanming Wang

8

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31 July 2017

Guo-Feng Huang

9

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31 July 2017

Manik L Debnath

10

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31 July 2017

language of work or name

English

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publication date

1 February 2002

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Bioorganic & Medicinal Chemistry Letters

31 July 2017

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31 July 2017

12

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31 July 2017

295-298

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31 July 2017

3

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Biological markers of Alzheimer's disease

31 July 2017

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Review of the next generation of Alzheimer's disease therapeutics: challenges for drug development

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Imaging Alzheimer's amyloid

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Development of small molecule probes for the Beta-amyloid protein of Alzheimer's Disease

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Synthesis and amyloid binding properties of rhenium complexes: preliminary progress toward a reagent for SPECT imaging of Alzheimer's disease brain.

1 reference

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99mTc-MAMA-chrysamine G, a probe for beta-amyloid protein of Alzheimer's disease

1 reference

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In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease

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7 January 2021

Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain

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Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates.

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Fundamentals of positron emission tomography and applications in preclinical drug development

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Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo

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Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy.

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Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy.

1 reference

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons.

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An improved synthesis of (3-N-[11C]methyl)spiperone

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10.1016/S0960-894X(01)00734-X

Identifiers

DOI

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31 July 2017

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