Metabolic consequence of long-term exposure of pancreatic beta cells to free fatty acid with special reference to glucose insensitivity (Q34108377)

31 July 2017

Metabolic consequence of long-term exposure of pancreatic beta cells to free fatty acid with special reference to glucose insensitivity (English)

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31 July 2017

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7

Yuji Matsuzawa

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31 July 2017

Katsumi Iizuka

1

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31 July 2017

Hiromu Nakajima

2

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31 July 2017

Mitsuyoshi Namba

3

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31 July 2017

Jun ichiro Miyagawa

4

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31 July 2017

Junichi Miyazaki

5

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31 July 2017

Toshiaki Hanafusa

6

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31 July 2017

language of work or name

English

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publication date

1 January 2002

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Biochimica et Biophysica Acta

31 July 2017

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31 July 2017

1586

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31 July 2017

1

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31 July 2017

23-31

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Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

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https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Fatty acids, lipotoxicity and insulin secretion

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https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Chronic perifusion of rat islets with palmitate suppresses glucose-stimulated insulin release

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https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Shared biochemical properties of glucotoxicity and lipotoxicity in islets decrease citrate synthase activity and increase phosphofructokinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

The coupling of metabolic to secretory events in pancreatic islets. The cytosolic redox state

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Role of NADP+ (corrected)-linked malic enzymes as regulators of the pool size of tricarboxylic acid-cycle intermediates in the perfused rat heart

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Glucose phosphorylation in mouse pancreatic islets

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from MIN6 and HIT cells

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Stable overexpression of the glucose-6-phosphatase catalytic subunit attenuates glucose sensitivity of insulin secretion from a mouse pancreatic beta-cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Transblot identification of biotin-containing proteins in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

The rat pyruvate carboxylase gene structure. Alternate promoters generate multiple transcripts with the 5'-end heterogeneity

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

A simple ultramicro method for determination of pyridine nucleotides in tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Role of membrane-anchored heparin-binding epidermal growth factor-like growth factor and CD9 on macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Regulation of oxidative phosphorylation in the mammalian cell

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (beta HC9).

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Regulation of rat pyruvate carboxylase gene expression by alternate promoters during development, in genetically obese rats and in insulin-secreting cells. Multiple transcripts with 5'-end heterogeneity modulate translation

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Long-term elevation of free fatty acids leads to delayed processing of proinsulin and prohormone convertases 2 and 3 in the pancreatic beta-cell line MIN6.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Enhanced de novo lipogenesis in the leptin-unresponsive pancreatic islets of prediabetic Zucker diabetic fatty rats: role in the pathogenesis of lipotoxic diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic beta-cell line INS-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

Thiol-dependent and Non-thiol-dependent Stimulations of Insulin Release

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

27-hydroxylated low density lipoprotein (LDL) cholesterol can be converted to 7alpha,27-dihydroxy-4-cholesten-3-one (cytosterone) before suppressing cholesterol production in normal human fibroblasts. Evidence that an altered metabolism of ldl chole

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900082-5

7 January 2021

10.1016/S0925-4439(01)00082-5

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DOI

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31 July 2017

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