The structural basis for the remarkable catalytic proficiency of orotidine 5'-monophosphate decarboxylase (Q34103427)

31 July 2017

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title

The structural basis for the remarkable catalytic proficiency of orotidine 5'-monophosphate decarboxylase (English)

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31 July 2017

Begley TP

1

1 reference

PubMed ID

11114509

31 July 2017

Appleby TC

series ordinal

2

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PubMed ID

11114509

31 July 2017

Ealick SE

series ordinal

3

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31 July 2017

1 December 2000

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Current Opinion in Structural Biology

31 July 2017

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31 July 2017

10

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31 July 2017

6

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31 July 2017

711-718

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https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900148-2

31 July 2017

1 reference

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Mechanism of decarboxylation of 1,3-dimethylorotic acid. A model for orotidine 5'-phosphate decarboxylase

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7 January 2021

The mechanism of orotidine 5'-monophosphate decarboxylase: catalysis by destabilization of the substrate

1 reference

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7 January 2021

A proficient enzyme revisited: the predicted mechanism for orotidine monophosphate decarboxylase

1 reference

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Model chemistry for a covalent mechanism of action of orotidine 5'-phosphate decarboxylase

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The crystal structure and mechanism of orotidine 5'-monophosphate decarboxylase

1 reference

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Electrostatic stress in catalysis: Structure and mechanism of the enzyme orotidine monophosphate decarboxylase

1 reference

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7 January 2021

Anatomy of a proficient enzyme: The structure of orotidine 5'-monophosphate decarboxylase in the presence and absence of a potential transition state analog

1 reference

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7 January 2021

Structural basis for the catalytic mechanism of a proficient enzyme: orotidine 5'-monophosphate decarboxylase

1 reference

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7 January 2021

Analysis of ground-state and transition-state effects in enzyme catalysis

1 reference

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7 January 2021

Contribution of enzyme-phosphoribosyl contacts to catalysis by orotidine 5'-phosphate decarboxylase.

1 reference

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Investigation of the enzymatic mechanism of yeast orotidine-5'-monophosphate decarboxylase using 13C kinetic isotope effects

1 reference

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7 January 2021

Determination of the mechanism of orotidine 5'-monophosphate decarboxylase by isotope effects

1 reference

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Orotidine-5'-monophosphate decarboxylase catalysis: kinetic isotope effects and the state of hybridization of a bound transition-state analogue

1 reference

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A unique catalytic and inhibitor-binding role for Lys93 of yeast orotidylate decarboxylase

1 reference

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Orotidylate decarboxylase: insights into the catalytic mechanism from substrate specificity studies

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Inhibition of orotidine-5'-phosphate decarboxylase by 1-(5'-phospho-beta-d-ribofuranosyl)barbituric acid, 6-azauridine 5'-phosphate, and uridine 5'-phosphate

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Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target

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Mechanistic studies of a protonolytic organomercurial cleaving enzyme: bacterial organomercurial lyase

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Reactions with Molecular Hydrogen in Microorganisms: Evidence for a Purely Organic Hydrogenation Catalyst

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Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11114509