The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans (Q34097744)

31 July 2017

4 references

30 June 2019

14 September 2019

28 September 2019

23 August 2022

The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans (English)

1 reference

31 July 2017

1 reference

14 September 2019

1 reference

14 September 2019

1 reference

28 September 2019

Ellen Miranda Leffler

series ordinal

2

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Laure Ségurel

object named as

Laure Ségurel

series ordinal

1

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author name string

Molly Przeworski

series ordinal

3

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PubMed ID

22162947

31 July 2017

language of work or name

English

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publication date

6 December 2011

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PubMed ID

22162947

31 July 2017

1 December 2011

4 references

30 June 2019

14 September 2019

28 September 2019

23 August 2022

5 references

31 July 2017

30 June 2019

14 September 2019

28 September 2019

23 August 2022

9

1 reference

31 July 2017

12

1 reference

31 July 2017

e1001211

1 reference

Creative Commons Attribution 4.0 International

31 July 2017

4 references

30 June 2019

14 September 2019

28 September 2019

Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination

23 August 2022

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

The landscape of recombination in African Americans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Variation in human recombination rates and its genetic determinants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

A map of human genome variation from population-scale sequencing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Prdm9 controls activation of mammalian recombination hotspots

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Distinct histone modifications define initiation and repair of meiotic recombination in the mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

The rise and fall of a human recombination hot spot

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Genome-wide control of the distribution of meiotic recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Evolution of the Drosophila nuclear pore complex results in multiple hybrid incompatibilities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Single-nucleotide polymorphisms of the PRDM9 (MEISETZ) gene in patients with nonobstructive azoospermia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

The recombinational anatomy of a mouse chromosome.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Keep your fingers off my DNA: protein-protein interactions mediated by C2H2 zinc finger domains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Live hot, die young: transmission distortion in recombination hotspots

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

A histone H3 methyltransferase controls epigenetic events required for meiotic prophase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

A fine-scale map of recombination rates and hotspots across the human genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Role of the N-terminal domain of the human DMC1 protein in octamer formation and DNA binding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Absence of the TAP2 human recombination hotspot in chimpanzees

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Comparative linkage-disequilibrium analysis of the beta-globin hotspot in primates

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Meiotic recombination hot spots and cold spots

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

To err (meiotically) is human: the genesis of human aneuploidy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

The hotspot conversion paradox and the evolution of meiotic recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Hybrid sterility in the mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232208

Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites.

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

Genome-wide analysis reveals novel molecular features of mouse recombination hotspots

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

A common sequence motif associated with recombination hot spots and genome instability in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

Polymorphism in the activity of human crossover hotspots independent of local DNA sequence variation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

Fine-scale recombination patterns differ between chimpanzees and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

Comparison of fine-scale recombination rates in humans and chimpanzees.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

Fine-scale recombination rate differences between sexes, populations and individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

A mouse speciation gene encodes a meiotic histone H3 methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

Factors influencing recombination frequency and distribution in a human meiotic crossover hotspot.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

21 January 2018

PRDM9 marks the spot.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

What are the genomic drivers of the rapid evolution of PRDM9?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001211

10.1371/JOURNAL.PBIO.1001211

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

PubMed ID

22162947