Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model (Q34095672)

31 July 2017

Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model (English)

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31 July 2017

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3

Russell E Ware

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31 July 2017

Jeffrey D Lebensburger

1

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31 July 2017

Tamara I Pestina

2

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31 July 2017

Kelli L Boyd

4

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31 July 2017

Derek A Persons

5

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31 July 2017

7 April 2010

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31 July 2017

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31 July 2017

95

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31 July 2017

9

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31 July 2017

1599-1603

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Correction of murine sickle cell disease using gamma-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Outcome of sickle cell anemia: a 4-decade observational study of 1056 patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Hydroxyurea and sickle cell anemia. Clinical utility of a myelosuppressive "switching" agent. The Multicenter Study of Hydroxyurea in Sickle Cell Anemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Interactions between human hemoglobins: sickling and related phenomena

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Preservation of spleen and brain function in children with sickle cell anemia treated with hydroxyurea.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Effects of hydroxyurea on the membrane of erythrocytes and platelets in sickle cell anemia.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Mortality in sickle cell disease. Life expectancy and risk factors for early death.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930964

Impaired nitric oxide-mediated vasodilation in transgenic sickle mouse

28 October 2018

1 reference

12 December 2020

Transgenic sickle mice have vascular inflammation

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12 December 2020

Fetal haemoglobin production and the sickle gene in the oases of Eastern Saudi Arabia

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12 December 2020

Is there a threshold level of fetal hemoglobin that ameliorates morbidity in sickle cell anemia?

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12 December 2020

Pain in sickle cell disease. Rates and risk factors

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12 December 2020

A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy

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12 December 2020

Decrease of very late activation antigen-4 and CD36 on reticulocytes in sickle cell patients treated with hydroxyurea

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12 December 2020

Hereditary persistence of fetal hemoglobin. A family study

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12 December 2020

Hydroxyurea therapy decreases the in vitro adhesion of sickle erythrocytes to thrombospondin and laminin

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12 December 2020

10.3324/HAEMATOL.2010.023325

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DOI

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31 July 2017

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31 July 2017

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