Total synthesis of fostriecin: via a regio- and stereoselective polyene hydration, oxidation, and hydroboration sequence (Q34088341)

30 July 2017

Total synthesis of fostriecin: via a regio- and stereoselective polyene hydration, oxidation, and hydroboration sequence (English)

1 reference

30 July 2017

1 reference

Dong Gao

1

1 reference

PubMed ID

20687585

30 July 2017

George A O'Doherty

series ordinal

2

1 reference

PubMed ID

20687585

30 July 2017

language of work or name

English

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publication date

1 September 2010

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30 July 2017

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30 July 2017

12

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30 July 2017

17

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30 July 2017

3752-3755

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Total synthesis, assignment of the relative and absolute stereochemistry, and structural reassignment of phostriecin (aka Sultriecin)

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

De novo formal synthesis of (-)-apicularen A via an iterative asymmetric hydration sequence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

De novo synthesis of 2-substituted syn-1,3-diols via an iterative asymmetric hydration strategy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Fostriecin: chemistry and biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Fostriecin: a review of the preclinical data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Novel microbial metabolites of the phoslactomycins family induce production of colony-stimulating factors by bone marrow stromal cells. I. Taxonomy, fermentation and biological properties.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Novel antitumor agents CI-920, PD 113,270 and PD 113,271. II. Isolation and characterization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

The biochemical pharmacology of CI-920, a structurally novel antibiotic with antileukemic activity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Novel antitumor antibiotic phospholine. 1. Production, isolation and characterization.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Studies on new phosphate ester antifungal antibiotics phoslactomycins. II. Structure elucidation of phoslactomycins A to F.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Studies on new phosphate ester antifungal antibiotics phoslactomycins. I. Taxonomy, fermentation, purification and biological activities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Enantio- and stereoselective route to the phoslactomycin family of antibiotics: formal synthesis of (+)-fostriecin and (+)-phoslactomycin B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Total synthesis of leustroducsin B.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Functionalization of organotrifluoroborates: reductive amination

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Formal total synthesis of fostriecin via 1,4-asymmetric induction using cobalt-alkyne complex.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

De novo asymmetric synthesis of milbemycin beta3 via an iterative asymmetric hydration approach

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Total synthesis of phoslactomycin B and its biosynthetic deamino precursor.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Catalyst-controlled asymmetric synthesis of fostriecin and 8-epi-fostriecin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

De novo asymmetric synthesis of anamarine and its analogues

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Dinuclear asymmetric Zn aldol additions: formal asymmetric synthesis of fostriecin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Total synthesis and biological evaluation of the protein phosphatase 2A inhibitor cytostatin and analogues

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Total synthesis of an antitumor antibiotic, Fostriecin (CI-920).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Total synthesis of leustroducsin B.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Total Synthesis of Fostriecin (CI-920) We thank Professor Andrew G. Myers and Scott E. Schaus for helpful discussions, and Dr. Alexandra E. Gould and Isabel K. Reichardt for important preliminary experimental work. We also thank Dr. Robert J. Schult

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Total synthesis of fostriecin (CI-920).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. I. Taxonomy, fermentation, isolation and biological activities.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Novel antitumor agents CI-920, PD 113,270 and PD 113,271. I. Taxonomy, fermentation and biological properties.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929272

Asymmetric total synthesis of (+)-phoslactomycin B

28 October 2018

1 reference

12 December 2020

Enantioselective syntheses of colletodiol, colletol, and grahamimycin A

1 reference

12 December 2020

In vitro activity of the novel antitumor antibiotic fostriecin (CI-920) in a human tumor cloning assay

1 reference

12 December 2020

Catalytic asymmetric synthesis of palmerolide A via organoboron methodology

1 reference

12 December 2020

Formal total synthesis of fostriecin

1 reference

12 December 2020

Total synthesis of fostriecin (CI-920) via a convergent route

1 reference

12 December 2020

Formal total synthesis of RK-397 via an asymmetric hydration and iterative allylation strategy

1 reference

12 December 2020

Purification of protein phosphatase 4 catalytic subunit: inhibition by the antitumour drug fostriecin and other tumour suppressors and promoters

1 reference

12 December 2020

Enantioselective synthesis of 10-epi-anamarine via an iterative dihydroxylation sequence

1 reference

12 December 2020

Versatile enantiocontrolled synthesis of (+)-fostriecin

1 reference

12 December 2020

Total synthesis of phoslactomycin A

1 reference

12 December 2020

A highly practical and enantioselective reagent for the allylation of aldehydes

1 reference

12 December 2020

Synthesis of Homoallylic Chiral Tertiary Alcohols via Chelation-Controlled Diastereoselective Nucleophilic Addition on α-Alkoxyketones: Application for the Synthesis of the C1−C11Subunit of 8-epi-Fostriecin

1 reference

12 December 2020

Novel antitumor antibiotic phospholine. 2. Structure determination

1 reference

12 December 2020

A Convergent Approach toward the C1−C11 Subunit of Phoslactomycins and Formal Synthesis of Phoslactomycin B

1 reference

12 December 2020

Titanocene-catalyzed regiodivergent epoxide openings

1 reference

12 December 2020

Convergent synthesis of fostriecin via selective alkene couplings and regioselective asymmetric dihydroxylation

1 reference

12 December 2020

Formal catalytic asymmetric total synthesis of fostriecin

1 reference

12 December 2020

Novel microbial metabolites of the phoslactomycins family induce production of colony-stimulating factors by bone marrow stromal cells. II. Isolation, physico-chemical properties and structure determination

1 reference

12 December 2020

Asymmetric total synthesis of (+)-fostriecin

1 reference

12 December 2020

Synthesis of the C1−C12 Fragment of Fostriecin

1 reference

12 December 2020

Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. II. Physico-chemical properties and structure determination

1 reference

12 December 2020

Identifiers

DOI

10.1021/OL101340N

1 reference

30 July 2017

1 reference

30 July 2017

1 reference

PubMed ID

20687585