The yeast two-hybrid system and its pharmaceutical significance (Q34087287)

30 July 2017

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title

The yeast two-hybrid system and its pharmaceutical significance (English)

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30 July 2017

Topcu Z

1

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PubMed ID

11087035

30 July 2017

Borden KL

series ordinal

2

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30 July 2017

1 September 2000

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30 July 2017

Pharmaceutical Research

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30 July 2017

17

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30 July 2017

9

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30 July 2017

1049-1055

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A yeast three-hybrid method to clone ternary protein complex components

30 July 2017

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12 December 2020

A simple method for the isolation and characterization of thymidylate uptaking mutants in Saccharomyces cerevisiae

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12 December 2020

A conditionally expressed third partner stabilizes or prevents the formation of a transcriptional activator in a three-hybrid system

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12 December 2020

High-throughput screening for drug discovery

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12 December 2020

A yeast genetic system for selecting small molecule inhibitors of protein-protein interactions in nanodroplets

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12 December 2020

Cycloheximide resistance in yeast: the gene and its portein

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12 December 2020

A novel genetic system to detect protein-protein interactions

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12 December 2020

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

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12 December 2020

Identification of mutations in p53 that affect its binding to SV40 large T antigen by using the yeast two-hybrid system

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12 December 2020

The complete code for a eukaryotic cell. Genome sequencing

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12 December 2020

Regulation of the yeast HO gene

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12 December 2020

An arenavirus RING (zinc-binding) protein binds the oncoprotein promyelocyte leukemia protein (PML) and relocates PML nuclear bodies to the cytoplasm.

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12 December 2020

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

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12 December 2020

A contingent replication assay for the detection of protein-protein interactions in animal cells

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12 December 2020

Fused protein domains inhibit DNA binding by LexA

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12 December 2020

Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12

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12 December 2020

Effects of polymyxin B sulfate and polymyxin B nonapeptide on growth and permeability of the yeast Saccharomyces cerevisiae.

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12 December 2020

The reverse two-hybrid system: a genetic scheme for selection against specific protein/protein interactions

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12 December 2020

Identification of a calcium channel modulator using a high throughput yeast two-hybrid screen

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12 December 2020

Mammalian mitochondrial DNA topoisomerase I preferentially relaxes supercoils in plasmids containing specific mitochondrial DNA sequences

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12 December 2020

A yeast mating-selection scheme for detection of protein-protein interactions

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12 December 2020

The impact of two-hybrid and related methods on biotechnology

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12 December 2020

A three-hybrid system for detecting small ligand-protein receptor interactions

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12 December 2020

A chemiluminescent assay for quantitation of β-galactosidase in the femtogram range: Application to quantitation of β-galactosidase in lacZ-transfected cells

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12 December 2020

The yeast gene ERG6 is required for normal membrane function but is not essential for biosynthesis of the cell-cycle-sparking sterol

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12 December 2020

Isolation of ORC6, a component of the yeast origin recognition complex by a one-hybrid system

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12 December 2020

The complete set of predicted genes from Saccharomyces cerevisiae in a readily usable form

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12 December 2020

A positive genetic selection for disrupting protein-protein interactions: identification of CREB mutations that prevent association with the coactivator CBP.

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12 December 2020

Yeast cells as tools for target-oriented screening

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12 December 2020

Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions

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12 December 2020

Investigating the biological functions of DNA topoisomerases in eukaryotic cells

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12 December 2020

LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones

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12 December 2020

Yeast multidrug resistance: the PDR network.

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12 December 2020

Yeast two-hybrid: so many interactions, (in) so little time...

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12 December 2020

Peptide mimetic drugs: a comment on progress and prospects

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12 December 2020

Protein-protein interactions: methods for detection and analysis

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12 December 2020

Yeast forward and reverse 'n'-hybrid systems

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12 December 2020

Structure and function of the yeast URA3 gene differentially regulated expression of hybrid β-galactosidase from overlapping coding sequences in yeast

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12 December 2020

Dual reporter systems in yeast and mammalian cells for assessing progesterone receptor modulators

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12 December 2020

DNA sequence selectivity of topoisomerases and topoisomerase poisons.

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12 December 2020

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

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12 December 2020

Gene identification using the yeast two-hybrid system

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12 December 2020

Identification of proteins that interact with a protein of interest: applications of the yeast two-hybrid system

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12 December 2020

A protein linkage map of Escherichia coli bacteriophage T7.

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12 December 2020

Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system

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12 December 2020

The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control

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12 December 2020

The design and synthesis of substituted biphenyl libraries

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12 December 2020

Encoded combinatorial chemistry

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12 December 2020

Chromatography of complex protein mixtures

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12 December 2020

Identifiers

DOI

10.1023/A:1026493310144

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30 July 2017

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PubMed ID

11087035