Can antioxidants be beneficial in the treatment of lead poisoning? (Q34085456)

30 July 2017

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title

Can antioxidants be beneficial in the treatment of lead poisoning? (English)

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30 July 2017

0 references

1 reference

Gurer H

1

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PubMed ID

11084283

30 July 2017

Ercal N

series ordinal

2

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PubMed ID

11084283

30 July 2017

language of work or name

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1 November 2000

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Free Radical Biology and Medicine

30 July 2017

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30 July 2017

29

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30 July 2017

927-945

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30 July 2017

10

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MECHANISMS OF LIPID PEROXIDE FORMATION IN TISSUES. ROLE OF METALS AND HAEMATIN PROTEINS IN THE CATALYSIS OF THE OXIDATION UNSATURATED FATTY ACIDS.

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead-catalyzed peroxidation of essential unsaturated fatty acid

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead-induced regional lipid peroxidation in brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Evaluation of malondialdehyde as an index of lead damage in rat brain homogenates

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Effect of lead on lipid peroxidation in liver of rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead-induced lipid peroxidation and antioxidant defense components of developing chick embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead intoxication: antioxidant defenses and oxidative damage in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Is lead toxicosis a reflection of altered fatty acid composition of membranes?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

An age-specific kinetic model of lead metabolism in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Filterability of Erythrocytes from Vitamin E-deficient Lead-poisoned Rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Nonrandom shortening of red cell survival times in men exposed to lead.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Studies on sodium-potassium-activated adenosinetriphosphatase. V. Correlation of enzyme activity with cation flux in six tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Deficient red cell membrane /Na++K+/-ATPase in lead poisoning.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Erythrocyte lead‐binding protein after occupational exposure. II. Influence on lead inhibition of membrane Na+,K+‐adenosinetriphosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Dietary modification of lead toxicity: effects on fatty acid and eicosanoid metabolism in chicks.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead-induced tissue fatty acid alterations and lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Relationship between the hemolytic action of heavy metals and lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Copper-induced generation of superoxide in human red cell membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The effect of lead on hemoglobin-catalyzed lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead-hemoglobin interaction as a possible source of reactive oxygen species--a chemiluminescent study.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Activated oxygen and haemolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Biomonitoring lead exposure with delta-aminolevulinate dehydratase (ALA-D) activity ratios

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Free radical generation during delta-aminolevulinic acid autoxidation: induction by hemoglobin and connections with porphyrinpathies

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Free radicals involvement in neurological porphyrias and lead poisoning

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Damage to rat liver mitochondria promoted by delta-aminolevulinic acid-generated reactive oxygen species: connections with acute intermittent porphyria and lead-poisoning

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

How do Ca2+ and 5-aminolevulinic acid-derived oxyradicals promote injury to isolated mitochondria?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Generation of active oxygen species during coupled autoxidation of oxyhemoglobin and delta-aminolevulinic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

DNA Alkylation by 4,5-Dioxovaleric Acid, the Final Oxidation Product of 5-Aminolevulinic Acid

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Hydroxyl radicals are involved in the oxidation of isolated and cellular DNA bases by 5-aminolevulinic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Changes in organ nonprotein sulfhydryl and glutathione concentrations during acute and chronic administration of inorganic lead to chicks

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead toxicity as related to glutathione metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Serum lipid peroxide level and blood superoxide dismutase activity in workers with occupational exposure to lead

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Indices of lead-exposure in blood and urine of lead-exposed workers and concentrations of major and trace elements and activities of SOD, GSH-Px and catalase in their blood

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Effects of exposure to lead on selected biochemical and haematological variables

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Biochemical effects of mercury, cadmium, and lead

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Metal-induced alterations of delta-aminolevulinic acid dehydratase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Effect of lead on -aminolevulinic acid dehydrase activity in red blood cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The influence of pH and methylene blue on the pathways of glucose utilization and lactate formation in erythrocytes of man.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The effect of lead on oxidative hemolysis and erythrocyte defense mechanisms in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Effects of short-term occupational exposure to lead on erythrocyte glucose-6-phosphate dehydrogenase activity and serum cholesterol

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Erythrocyte enzymes in experimental lead poisoning

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

1 reference

7 January 2021

In vitro assessment of the toxicity of metal compounds : IV. Disposition of metals in cells: Interactions with membranes, glutathione, metallothionein, and DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Nuclear magnetic resonance studies of the solution chemistry of metal complexes. IX. Binding of cadmium, zinc, lead, and mercury by glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Effect of diet on the response in rats to lead acetate given orally or in the drinking water

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lipoperoxidative damage on lead exposure in rat brain and its implications on membrane bound enzymes.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Role of selenium against lead toxicity in male rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Studies on the biosynthesis of blood pigments. I. Haem synthesis in haemolysed erythrocytes of chicken blood

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Erythrocyte superoxide dismutase activity and other parameters of copper status in rats ingesting lead acetate

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead and mercury mutagenesis: role of H2O2, superoxide dismutase, and xanthine oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The use of chelating agents in occupational lead poisoning

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Chelation therapy for childhood lead poisoning. The changing scene in the 1990s

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Hemolysis During BAL Chelation Therapy For High Blood Lead Levels in Two G6PD Deficient Children

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Management of childhood lead poisoning.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Mobilization of heavy metals by newer, therapeutically useful chelating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

New developments in pediatric lead poisoning.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Evaluation of the potential role of chelation therapy in treatment of low to moderate lead exposures

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Penicillamine, a new oral therapy for Wilson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Oral chelators for childhood lead poisoning

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The use of chelating agents in the treatment of acute and chronic lead intoxication in childhood

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Oral penicillamine therapy for chronic lead poisoning in children

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Efficacy and toxicity of d-penicillamine in low-level lead poisoning

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Reduction in oral penicillamine absorption by food, antacid, and ferrous sulfate.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Pharmacokinetics of oral 500-mg penicillamine: effect of antacids on absorption.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Controlled study of meso-2,3-dimercaptosuccinic acid for the management of childhood lead intoxication

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Influence of vitamin B6 status on aspects of lead poisoning in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Thiamine and zinc in prevention or therapy of lead intoxication

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Interaction of zinc, methionine or their combination with lead at gastrointestinal or post-absorptive level in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Influence of thiamine and ascorbic acid supplementation on the antidotal efficacy of thiol chelators in experimental lead intoxication

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Influence of pyridoxine (vitamin B6) on lead intoxication in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Beneficial effects of zinc supplementation during chelation treatment of lead intoxication in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The physiological role of zinc as an antioxidant

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Relationship of ascorbic acid to blood lead levels

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Interactions of dietary lead with fish oil and antioxidant in chicks

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Diabetes-induced metabolic abnormalities in myocardium: effect of antioxidant therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Fumonisin B1-induced DNA damage in rat liver and spleen: effects of pretreatment with coenzyme Q10, L-carnitine, alpha-tocopherol and selenium

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Ethanol potentiates lead-induced inhibition of rat brain antioxidant defense systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Beneficial effects of S-adenosyl-L-methionine on aminolevulinic acid dehydratase, glutathione, and lipid peroxidation during acute lead-ethanol administration in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

In vivo indices of oxidative stress in lead-exposed C57BL/6 mice are reduced by treatment with meso-2,3-dimercaptosuccinic acid or N-acetylcysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

1 reference

7 January 2021

Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Acetylcysteine: a drug with an interesting past and a fascinating future

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lung protection by a thiol-containing antioxidant: N-acetylcysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Clinical pharmacokinetics of N-acetylcysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Experimental chelation therapy in chromium, lead, and boron intoxication with N-acetylcysteine and other compounds.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Comparison of the effectiveness of several chelators after single administration on the toxicity, excretion and distribution of cobalt

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Differential effect of N-acetylcysteine on excretion of the metals Hg, Cd, Pb and Au

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Does N-acetylcysteine increase the excretion of trace metals (calcium, magnesium, iron, zinc and copper) when given orally?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Effects of N-acetylcysteine and 2,3-dimercaptosuccinic acid on lead induced oxidative stress in rat lenses

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Pro-oxidant effects of delta-aminolevulinic acid (delta-ALA) on Chinese hamster ovary (CHO) cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Antioxidant role of alpha-lipoic acid in lead toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

32 Biosynthesis of lipoic acid via unsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

alpha-Lipoic acid as a biological antioxidant

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The pharmacology of the antioxidant lipoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Alpha-lipoic acid increases intracellular glutathione in a human T-lymphocyte Jurkat cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

alpha-Lipoic acid protects against reperfusion injury following cerebral ischemia in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Effects of some sulfur-containing antioxidants on lead-exposed lenses

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Direct scavenging of free radicals by captopril, an angiotensin converting enzyme inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Captopril as an antioxidant in lead-exposed Fischer 344 rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Cardiotoxicity and hypertension in rats after oral lead exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead-induced hypertension: interplay of nitric oxide and reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead-induced hypertension. II. Response to sequential infusions of L-arginine, superoxide dismutase, and nitroprusside

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Increased nitric oxide inactivation by reactive oxygen species in lead-induced hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead promotes hydroxyl radical generation and lipid peroxidation in cultured aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Taurine: biological update

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Physiological actions of taurine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Taurine and ellagic acid: two differently-acting natural antioxidants

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Taurine attenuates nitric oxide- and reactive oxygen intermediate-dependent hepatocyte injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The in vivo and in vitro protective properties of taurine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

The antioxidant action of taurine, hypotaurine and their metabolic precursors

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

Lead and IQ scores: a reanalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900413-5

7 January 2021

10.1016/S0891-5849(00)00413-5

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11084283