Adeno-associated virus vectors for gene therapy: more pros than cons? (Q34080580)

30 July 2017

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title

Adeno-associated virus vectors for gene therapy: more pros than cons? (English)

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30 July 2017

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Monahan PE

1

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PubMed ID

11074369

30 July 2017

Samulski RJ

series ordinal

2

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30 July 2017

1 November 2000

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Trends in Molecular Medicine

30 July 2017

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30 July 2017

6

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30 July 2017

11

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30 July 2017

433-440

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Site-specific integration by adeno-associated virus

30 July 2017

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Roles of adeno-associated virus Rep protein and human chromosome 19 in site-specific recombination

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

The kinetics of rAAV integration in the liver

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Adeno-associated virus site-specifically integrates into a muscle-specific DNA region

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Safety aspects of gene therapy

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Germline alteration by gene therapy: assessing and reducing the risks

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Risk potential of the chromosomal insertion of foreign DNA.

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Repeat transduction in the mouse lung by using adeno-associated virus vectors with different serotypes

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

The use of adeno-associated virus to circumvent the maturation-dependent viral transduction of muscle fibers

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Efficient gene transfer into human keratinocytes with recombinant adeno-associated virus vectors

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Peroral gene therapy of lactose intolerance using an adeno-associated virus vector

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Adeno-associated virus (AAV)-3-based vectors transduce haematopoietic cells not susceptible to transduction with AAV-2-based vectors

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Kinetics of recombinant adeno-associated virus-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Adeno-associated virus type 2-mediated gene transfer: correlation of tyrosine phosphorylation of the cellular single-stranded D sequence-binding protein with transgene expression in human cells in vitro and murine tissues in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Concatamerization of adeno-associated virus circular genomes occurs through intermolecular recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Recombinant adeno-associated virus for muscle directed gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibers

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Role of vector in activation of T cell subsets in immune responses against the secreted transgene product factor IX.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

CD40 ligand-dependent activation of cytotoxic T lymphocytes by adeno-associated virus vectors in vivo: role of immature dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

AAV vectors: is clinical success on the horizon?

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector.

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Quantitative analysis of the packaging capacity of recombinant adeno-associated virus

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Recombinant human parvovirus B19 vectors: erythroid cell-specific delivery and expression of transduced genes

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Novel transcriptional regulatory signals in the adeno-associated virus terminal repeat A/D junction element

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Trans-splicing vectors expand the utility of adeno-associated virus for gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Novel tools for production and purification of recombinant adenoassociated virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

High-titer adeno-associated viral vectors from a Rep/Cap cell line and hybrid shuttle virus

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901810-4

7 January 2021

10.1016/S1357-4310(00)01810-4

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11074369