JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo. (Q34078203)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20723011%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo (English)

1 reference

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10 February 2020

1 reference

angiogenesis inhibitor

1 reference

1 reference

1 reference

4

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10 February 2020

2

Kenneth C Anderson

1 reference

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10 February 2020

1

Tanyel Kiziltepe

1 reference

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10 February 2020

author name string

Jeffery L Kutok

3

1 reference

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10 February 2020

Kenneth M Boucher

5

1 reference

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10 February 2020

Joseph E Saavedra

6

1 reference

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10 February 2020

Larry K Keefer

7

1 reference

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10 February 2020

Paul J Shami

8

1 reference

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10 February 2020

publication date

1 January 2010

1 reference

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Journal of Pharmacy and Pharmacology

10 February 2020

published in

1 reference

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10 February 2020

volume

62

1 reference

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10 February 2020

issue

1

1 reference

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10 February 2020

page(s)

145-151

1 reference

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Gene expression profiling for nitric oxide prodrug JS-K to kill HL-60 myeloid leukemia cells

10 February 2020

cites work

1 reference

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Molecular mechanisms and clinical implications of reversible protein S-glutathionylation

5 July 2018

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The malignant clone and the bone-marrow environment

5 July 2018

1 reference

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JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2925308

Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

5 July 2018

1 reference

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A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins

5 July 2018

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Endothelial cell effects of cytotoxics: balance between desired and unwanted effects.

5 July 2018

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Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator

5 July 2018

1 reference

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Proteomic study of human umbilical vein endothelial cells in culture

5 July 2018

1 reference

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JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity

5 July 2018

1 reference

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Angiogenesis assays: a critical overview

5 July 2018

1 reference

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Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide

5 July 2018

1 reference

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Selective protein arylation and acetaminophen-induced hepatotoxicity

5 July 2018

1 reference

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Nitric oxide modulation of the growth and differentiation of freshly isolated acute non-lymphocytic leukemia cells

5 July 2018

1 reference

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Evidence that nitric oxide is an endogenous antiangiogenic mediator

5 July 2018

1 reference

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Nitric oxide: physiology, pathophysiology, and pharmacology

5 July 2018

1 reference

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Nitric oxide modulation of human leukemia cell differentiation and gene expression

5 July 2018

1 reference

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Nitric oxide as a secretory product of mammalian cells

5 July 2018

1 reference

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Multidrug resistance in leukaemia

5 July 2018

1 reference

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The secondary amine/nitric oxide complex ion R(2)N[N(O)NO](-) as nucleophile and leaving group in S9N)Ar reactions

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1211%2FJPP.62.01.0017

Prognostic value of bone marrow angiogenesis in patients with multiple myeloma undergoing high-dose therapy.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1211%2FJPP.62.01.0017

Evidence for the involvement of the glutathione pathway in drug resistance in AML.

21 January 2018

1 reference

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Antiangiogenic effects of S-nitrosocaptopril crystals as a nitric oxide donor

28 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1211%2FJPP.62.01.0017

Prognostic value of bone marrow angiogenesis in multiple myeloma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20723011

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Schedule and concentration-dependent induction of apoptosis in leukemia cells by nitric oxide

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20723011

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1211/JPP.62.01.0017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20723011%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20723011%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

20723011

1 reference