Robust identification of binding hot spots using continuum electrostatics: application to hen egg-white lysozyme (Q34076535)

30 July 2017

Robust identification of binding hot spots using continuum electrostatics: application to hen egg-white lysozyme (English)

1 reference

30 July 2017

Dima Kozakov

5

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Sandor Vajda

object named as

Sandor Vajda

6

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author name string

David H Hall

1

1 reference

30 July 2017

Laurie E Grove

2

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30 July 2017

Christine Yueh

3

1 reference

30 July 2017

Chi Ho Ngan

4

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30 July 2017

language of work or name

English

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publication date

1 December 2011

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Journal of the American Chemical Society

30 July 2017

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30 July 2017

133

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30 July 2017

20668-20671

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30 July 2017

51

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Structural conservation of druggable hot spots in protein-protein interfaces

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Full protein flexibility is essential for proper hot-spot mapping.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Binding hot spots and amantadine orientation in the influenza a virus M2 proton channel

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Importance of the hydrogen bonding network including Asp52 for catalysis, as revealed by Asn59 mutant hen egg-white lysozymes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Fragment-based identification of druggable 'hot spots' of proteins using Fourier domain correlation techniques

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Druggability indices for protein targets derived from NMR-based screening data

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Experimental and computational mapping of the binding surface of a crystalline protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

X-ray studies on cross-linked lysozyme crystals in acetonitrile-water mixture

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Structural changes of active site cleft and different saccharide binding modes in human lysozyme co-crystallized with hexa-N-acetyl-chitohexaose at pH 4.0

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

A hot spot of binding energy in a hormone-receptor interface

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Lysozyme revisited: Crystallographic evidence for distortion of an N-acetylmuramic acid residue bound in site D

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Structural analysis of denaturant-protein interactions: comparison between the effects of bromoethanol and SDS on denaturation and renaturation of triclinic lysozyme.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Identification of hot spots within druggable binding regions by computational solvent mapping of proteins.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Multiple solvent crystal structures: probing binding sites, plasticity and hydration

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Binding of N-acetylglucosamine oligosaccharides to hen egg-white lysozyme: a powder diffraction study

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Locating and characterizing binding sites on proteins

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

1H nuclear magnetic resonance studies of hen lysozyme-N-acetylglucosamine oligosaccharide complexes in solution. Application of chemical shifts for the comparison of conformational changes in solution and in the crystal

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

A structural basis for the interaction of urea with lysozyme

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244821

Study of ethanol-lysozyme interactions using neutron diffraction

28 October 2018

1 reference

12 December 2020

Binding of dimethyl sulfoxide to lysozyme in crystals, studied with neutron diffraction

1 reference

12 December 2020

Organic solvents identify specific ligand binding sites on protein surfaces

1 reference

12 December 2020

Diverse fragment clustering and water exclusion identify protein hot spots

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA207914Y

1 reference

30 July 2017

1 reference

30 July 2017

1 reference