Thyroid hormone receptor α mutation causes a severe and thyroxine-resistant skeletal dysplasia in female mice. (Q34068384)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24914936%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Thyroid hormone receptor α mutation causes a severe and thyroxine-resistant skeletal dysplasia in female mice (English)

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20 March 2020

5

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20 March 2020

author name string

J H Duncan Bassett

1

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20 March 2020

Alan Boyde

2

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20 March 2020

Tomas Zikmund

3

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20 March 2020

Holly Evans

4

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20 March 2020

Xuguang Zhu

6

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20 March 2020

Jeong Won Park

7

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20 March 2020

Sheue-yann Cheng

8

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20 March 2020

Graham R Williams

9

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20 March 2020

language of work or name

English

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publication date

10 June 2014

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20 March 2020

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20 March 2020

volume

155

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20 March 2020

issue

9

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20 March 2020

page(s)

3699-3712

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Creative Commons Attribution 3.0 Unported

20 March 2020

copyright license

start time

23 November 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4138578/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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An adult female with resistance to thyroid hormone mediated by defective thyroid hormone receptor α.

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Differential recruitment of nuclear coregulators directs the isoform-dependent action of mutant thyroid hormone receptors

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Characterization of skeletal phenotypes of TRalpha1 and TRbeta mutant mice: implications for tissue thyroid status and T3 target gene expression

5 July 2018

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The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

5 July 2018

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The thyroid hormone receptor beta-specific agonist GC-1 selectively affects the bone development of hypothyroid rats

5 July 2018

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5 July 2018

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A targeted dominant negative mutation of the thyroid hormone alpha 1 receptor causes increased mortality, infertility, and dwarfism in mice

5 July 2018

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Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus

5 July 2018

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Distinct tissue-specific roles for thyroid hormone receptors beta and alpha1 in regulation of type 1 deiodinase expression

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5 July 2018

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Improved radioimmunoassay for measurement of mouse thyrotropin in serum: strain differences in thyrotropin concentration and thyrotroph sensitivity to thyroid hormone

5 July 2018

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5 July 2018

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Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor

5 July 2018

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Mineral density quantitation of the human cortical iliac crest by backscattered electron image analysis: variations with age, sex, and degree of osteoarthritis

5 July 2018

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Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone

5 July 2018

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5 July 2018

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Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain

5 July 2018

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Morphometric and Dynamic Studies of Bone Changes in Hypothyroidism

5 July 2018

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Effect of antithyroid treatment on calcium-phosphorus metabolism in hyperthyroidism. II: Bone histomorphometry

5 July 2018

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RTHα, a newly recognized phenotype of the resistance to thyroid hormone (RTH) syndrome in patients with THRA gene mutations

5 July 2018

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The contribution of hip geometry to the prediction of hip osteoarthritis

28 October 2018

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A mutation in the thyroid hormone receptor alpha gene.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Thyroid hormone receptor β mediates thyroid hormone effects on bone remodeling and bone mass.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Thyroid function within the upper normal range is associated with reduced bone mineral density and an increased risk of nonvertebral fractures in healthy euthyroid postmenopausal women.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Thyroid status during skeletal development determines adult bone structure and mineralization

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Thyroid hormones regulate fibroblast growth factor receptor signaling during chondrogenesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Contrasting skeletal phenotypes in mice with an identical mutation targeted to thyroid hormone receptor alpha1 or beta

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

A comparison of mechanical properties derived from multiple skeletal sites in mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Fractures in patients with hyperthyroidism and hypothyroidism: a nationwide follow-up study in 16,249 patients

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Longitudinal growth, sexual maturation and final height in patients with congenital hypothyroidism detected by neonatal screening

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138578

Thyroid hormone excess rather than thyrotropin deficiency induces osteoporosis in hyperthyroidism

28 October 2018

1 reference

12 December 2020

Thyroid hormone-stimulated differentiation of primary rib chondrocytes in vitro requires thyroid hormone receptor beta

1 reference

12 December 2020

Long-term growth in juvenile acquired hypothyroidism: the failure to achieve normal adult stature

1 reference

12 December 2020

Mice lacking the calcineurin inhibitor Rcan2 have an isolated defect of osteoblast function

1 reference

12 December 2020

Variations in articular calcified cartilage by site and exercise in the 18-month-old equine distal metacarpal condyle

1 reference

12 December 2020

Clinical phenotype and mutant TRα1

1 reference

12 December 2020

Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility

1 reference

12 December 2020

Kinetics of trabecular bone resorption and formation in hypothyroidism: evidence for a positive balance per remodeling cycle

1 reference

12 December 2020

Identifiers

DOI

10.1210/EN.2013-2156

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24914936%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24914936%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24914936%20AND%20SRC:MED&resulttype=core&format=json