Assembling the glycopeptide antibiotic scaffold: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009 (Q34066411)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12060705%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Assembling the glycopeptide antibiotic scaffold: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009 (English)

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9 November 2019

0 references

1 reference

ChEBI release 2020-05-28

ChEBI ID

29505

Streptomyces coelicolor

1 reference

inferred from

reverse claim

Streptomyces toyocaensis

1 reference

inferred from

reverse claim

Streptomyces albidoflavus

1 reference

1 reference

HRGFAEUWEMDRRZ-WTWZBVEQSA-N

1 reference

1 reference

7

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9 November 2019

6

Christopher T Walsh

1 reference

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9 November 2019

author name string

Jeff Pootoolal

1

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9 November 2019

Michael G Thomas

2

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9 November 2019

C Gary Marshall

3

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9 November 2019

John M Neu

4

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9 November 2019

Brian K Hubbard

5

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9 November 2019

language of work or name

English

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publication date

11 June 2002

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full work available at URL

9 November 2019

https://europepmc.org/articles/pmc124406?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1073/pnas.102285099?email=unpaywall_01@example.com

published in

Proceedings of the National Academy of Sciences of the United States of America

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9 November 2019

volume

99

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9 November 2019

issue

13

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9 November 2019

page(s)

8962-8967

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9 November 2019

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19 March 2024

https://api.unpaywall.org/v2/10.1073/pnas.102285099?email=unpaywall_01@example.com

access restriction status

open access

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inferred from online access status

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Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908

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DdlN from vancomycin-producing Amycolatopsis orientalis C329.2 is a VanA homologue with D-alanyl-D-lactate ligase activity.

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D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB

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Denaturation of circular or linear DNA facilitates targeted integrative transformation of Streptomyces coelicolor A3(2): possible relevance to other organisms

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Bacterial resistance to vancomycin: five genes and one missing hydrogen bond tell the story

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The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147

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Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase

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The gene cluster for chloramphenicol biosynthesis in Streptomyces venezuelae ISP5230 includes novel shikimate pathway homologues and a monomodular non-ribosomal peptide synthetase gene

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Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency, stereoselectivity and regulation with implications for function.

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Purification and Characterization of Two Haloperoxidases from the Glycopeptide Antibiotic ProducerStreptomyces toyocaensisNRRL 15009

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12 December 2020

The Biosynthesis of Vancomycin-Type Glycopeptide Antibiotics-The Order of the Cyclization Steps This work was supported by the Deutsche Forschungsgemeinschaft (SFB 323) and by a grant of the EU (MEGATOP, QLK3-1999-00650). R. D. S. gratefully acknowl

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12 December 2020

The glycopeptide antibiotic producer Streptomyces toyocaensis NRRL 15009 has both D-alanyl-D-alanine and D-alanyl-D-lactate ligases

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12 December 2020

A gene cloning system for 'Streptomyces toyocaensis'

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12 December 2020

A versatile quick-prep of genomic DNA from gram-positive bacteria

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12 December 2020

Structure of balhimycin and its complex with solvent molecules

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12 December 2020

Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium

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12 December 2020

The Biosynthesis of Vancomycin-Type Glycopeptide Antibiotics-New Insights into the Cyclization Steps This work was supported by the Deutsche Forschungsgemeinschaft (SFB 323). We thank M. Schierle, Dr. S. Stevanovic and Prof. H.-G. Rammensee for help

1 reference

12 December 2020

Molecular Mechanism of VanHst, an α-Ketoacid Dehydrogenase Required for Glycopeptide Antibiotic Resistance from a Glycopeptide Producing Organism†

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12 December 2020

Mutational analysis of the epimerization domain in the initiation module PheATE of gramicidin S synthetase

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12 December 2020

Identifiers

DOI

10.1073/PNAS.102285099

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12060705%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

0 references

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9 November 2019

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