Genus beta human papillomavirus E6 proteins vary in their effects on the transactivation of p53 target genes. (Q34057911)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24850740%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

Genus beta human papillomavirus E6 proteins vary in their effects on the transactivation of p53 target genes (English)

1 reference

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18 March 2020

4

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18 March 2020

author name string

Elizabeth A White

series ordinal

1

1 reference

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18 March 2020

Johanna Walther

series ordinal

2

1 reference

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18 March 2020

Hassan Javanbakht

series ordinal

3

1 reference

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18 March 2020

language of work or name

English

0 references

publication date

21 May 2014

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18 March 2020

1 reference

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18 March 2020

volume

88

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18 March 2020

issue

15

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18 March 2020

page(s)

8201-8212

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The MDM2-p53 pathway revisited

18 March 2020

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5 July 2018

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5 July 2018

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Cutaneous β-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling.

5 July 2018

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MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin γ2 expression in oral dysplasia and squamous cell carcinoma.

5 July 2018

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Next-generation sequencing fails to identify human virus sequences in cutaneous squamous cell carcinoma

5 July 2018

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Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling

5 July 2018

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Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.

5 July 2018

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5 July 2018

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Cutaneous HPV23 E6 prevents p53 phosphorylation through interaction with HIPK2.

5 July 2018

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Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

5 July 2018

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Transcriptome sequencing demonstrates that human papillomavirus is not active in cutaneous squamous cell carcinoma

5 July 2018

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Modulation of TGF-β-inducible hypermotility by EGF and other factors in human prostate epithelial cells and keratinocytes

5 July 2018

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Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments

5 July 2018

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Viral-associated nonmelanoma skin cancers: a review

5 July 2018

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Betapapillomaviruses: innocent bystanders or causes of skin cancer

5 July 2018

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E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation

5 July 2018

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Comparative transforming potential of different human papillomaviruses associated with non-melanoma skin cancer

5 July 2018

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Skin human papillomavirus type 38 alters p53 functions by accumulation of deltaNp73.

5 July 2018

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HPV-associated skin disease.

5 July 2018

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Repair of UV-induced thymine dimers is compromised in cells expressing the E6 protein from human papillomaviruses types 5 and 18.

5 July 2018

1 reference

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Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression.

5 July 2018

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UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair

5 July 2018

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Chapter 8: Human papillomavirus and skin cancer.

5 July 2018

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The E6 and E7 proteins of the cutaneous human papillomavirus type 38 display transforming properties

5 July 2018

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5 July 2018

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p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

5 July 2018

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Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins

5 July 2018

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E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage

5 July 2018

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Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

The mitomycin bioreductive antitumor agents: cross-linking and alkylation of DNA as the molecular basis of their activity

5 July 2018

1 reference

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

Mutation of phosphoserine 389 affects p53 function in vivo

5 July 2018

1 reference

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Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

Phosphorylation at Ser-15 and Ser-392 in mutant p53 molecules from human tumors is altered compared to wild-type p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

Functional p53 protein in human papillomavirus-positive cancer cells.

5 July 2018

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Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells

5 July 2018

1 reference

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Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product

5 July 2018

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HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes

5 July 2018

1 reference

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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

5 July 2018

1 reference

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Association of human papillomavirus types 16 and 18 E6 proteins with p53.

5 July 2018

1 reference

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins

5 July 2018

1 reference

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Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

5 July 2018

1 reference

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T antigen is bound to a host protein in SY40-transformed cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

Beta human papillomavirus E6 expression inhibits stabilization of p53 and increases tolerance of genomic instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

Comparative analysis of transforming properties of E6 and E7 from different beta human papillomavirus types.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

p53 mutations are common in human papillomavirus type 38-positive non-melanoma skin cancers

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

Neocarzinostatin induces an effective p53-dependent response in human papillomavirus-positive cervical cancer cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135955

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24850740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cellular responses of HPV-positive cancer cells to genotoxic anti-cancer agents: repression of E6/E7-oncogene expression and induction of apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24850740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

E6 oncoprotein represses p53-dependent gene activation via inhibition of protein acetylation independently of inducing p53 degradation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24850740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.01197-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24850740%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24850740%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference