Simian immunodeficiency virus infection of monkeys as a model system for the study of AIDS pathogenesis, treatment, and prevention (Q34050736)

30 July 2017

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title

Simian immunodeficiency virus infection of monkeys as a model system for the study of AIDS pathogenesis, treatment, and prevention (English)

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Simian immunodeficiency virus

30 July 2017

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author name string

Hirsch VM

series ordinal

1

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PubMed ID

11013771

30 July 2017

Lifson JD

series ordinal

2

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30 July 2017

1 January 2000

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30 July 2017

Advances in Pharmacology

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30 July 2017

49

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30 July 2017

437-477

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HIV-1 recombinant poxvirus vaccine induces cross-protection against HIV-2 challenge in rhesus macaques

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Infection of Macaca nemestrina by human immunodeficiency virus type-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Reduced virus load in rhesus macaques immunized with recombinant gp160 and challenged with simian immunodeficiency virus.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Immunogenicity and protective efficacy of a human immunodeficiency virus type 2 recombinant canarypox (ALVAC) vaccine candidate in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Necropsy findings in rhesus monkeys experimentally infected with cultured simian immunodeficiency virus (SIV)/delta

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Simian immunodeficiency virus (SIV) from sun-tailed monkeys (Cercopithecus solatus): evidence for host-dependent evolution of SIV within the C. lhoesti superspecies.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Lack of dichotomy between virus load of peripheral blood and lymph nodes during long-term simian immunodeficiency virus infection of African green monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Recombinant vaccine-induced protection against the highly pathogenic simian immunodeficiency virus SIV(mac251): dependence on route of challenge exposure.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Isolation of a lentivirus from a macaque with lymphoma: comparison with HTLV-III/LAV and other lentiviruses.

1 reference

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7 January 2021

Infectivity of titered doses of simian immunodeficiency virus clone E11S inoculated intravenously into rhesus macaques (Macaca mulatta).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Outcome of immunization of cynomolgus monkeys with recombinant Semliki Forest virus encoding human immunodeficiency virus type 1 envelope protein and challenge with a high dose of SHIV-4 virus.

1 reference

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7 January 2021

Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations

1 reference

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7 January 2021

Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine

1 reference

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7 January 2021

Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

An adenovirus-simian immunodeficiency virus env vaccine elicits humoral, cellular, and mucosal immune responses in rhesus macaques and decreases viral burden following vaginal challenge

1 reference

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7 January 2021

Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Cell lines for the production of recombinant adeno-associated virus

1 reference

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7 January 2021

Cross-protective immune responses induced in rhesus macaques by immunization with attenuated macrophage-tropic simian immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

A novel simian immunodeficiency virus (SIVdrl) pol sequence from the drill monkey, Mandrillus leucophaeus

1 reference

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7 January 2021

Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Isolation of T-cell tropic HTLV-III-like retrovirus from macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Safety, pharmacokinetics, and antiretroviral activity of intravenous 9-[2-(R)-(Phosphonomethoxy)propyl]adenine, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Sequence analysis and acute pathogenicity of molecularly cloned SIVSMM-PBj14.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Replicative capacity, cytopathic effect and cell tropism of HIV.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

A highly divergent proviral DNA clone of SIV from a distinct species of African green monkey.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Phylogenesis and genetic complexity of the nonhuman primate retroviridae

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Highly attenuated HIV type 2 recombinant poxviruses, but not HIV-2 recombinant Salmonella vaccines, induce long-lasting protection in rhesus macaques.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Gene gun-based nucleic acid immunization alone or in combination with recombinant vaccinia vectors suppresses virus burden in rhesus macaques challenged with a heterologous SIV.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Unique lentivirus--host interactions: SIVsmmPBj14 infection of macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Identification and biologic characterization of an acutely lethal variant of simian immunodeficiency virus from sooty mangabeys (SIV/SMM).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Natural infection of a household pet red-capped mangabey (Cercocebus torquatus torquatus) with a new simian immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Human infection by genetically diverse SIVSM-related HIV-2 in west Africa

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

A novel method for real time quantitative RT-PCR.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Protection from pathogenic SIV challenge using multigenic DNA vaccines

1 reference

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7 January 2021

Passive immune globulin therapy in the SIV/macaque model: early intervention can alter disease profile

1 reference

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7 January 2021

Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs.

1 reference

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7 January 2021

Critical role for CD4(+) T cells in controlling retrovirus replication and spread in persistently infected mice

1 reference

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7 January 2021

Real time quantitative PCR

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

An African primate lentivirus (SIVsm) closely related to HIV-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Pathogenic diversity of simian immunodeficiency viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

A molecularly cloned, pathogenic, neutralization-resistant simian immunodeficiency virus, SIVsmE543-3.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Phylogeny and natural history of the primate lentiviruses, SIV and HIV.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Vpx is required for dissemination and pathogenesis of SIV(SM) PBj: evidence of macrophage-dependent viral amplification.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Genetic organization of a chimpanzee lentivirus related to HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Phylogenetic analysis of a new chimpanzee lentivirus SIVcpz-gab2 from a wild-captured chimpanzee from Gabon

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Chimeric SHIV that causes CD4+ T cell loss and AIDS in rhesus macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Protective immunity induced by live attenuated simian immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Progress in the development of an HIV-1 vaccine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Infection of rhesus and cynomolgus macaques with a rapidly fatal SIV (SIVSMM/PBj) isolate from sooty mangabeys

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

The extent of early viral replication is a critical determinant of the natural history of simian immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Control of HIV despite the Discontinuation of Antiretroviral Therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Simian immunodeficiency virus DNA vaccine trial in macaques.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

HIV-1 vaccine candidate evaluation in non-human primates.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Rhesus macaques that become systemically infected with pathogenic SHIV 89.6-PD after intravenous, rectal, or vaginal inoculation and fail to make an antiviral antibody response rapidly develop AIDS

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Utility of SHIV for testing HIV-1 vaccine candidates in macaques.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Isolation of a simian immunodeficiency virus related to human immunodeficiency virus type 2 from a west African pet sooty mangabey

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Progesterone implants enhance SIV vaginal transmission and early virus load

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Spectrum of disease in macaque monkeys chronically infected with SIV/SMM.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Recombinant viruses as vectors for mucosal immunity

1 reference

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7 January 2021

Host range restricted, non-replicating vaccinia virus vectors as vaccine candidates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Isolation of an HTLV-III-related retrovirus from macaques with simian AIDS and its possible origin in asymptomatic mangabeys

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Multiple immunizations with attenuated poxvirus HIV type 2 recombinants and subunit boosts required for protection of rhesus macaques.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Multiple viral determinants contribute to pathogenicity of the acutely lethal simian immunodeficiency virus SIVsmmPBj variant

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Deletion of the nef gene abrogates the ability of SIV smmPBj to induce acutely lethal disease in pigtail macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Viral dynamics of primary viremia and antiretroviral therapy in simian immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Serum HIV-1 RNA levels and time to development of AIDS in the Multicenter Hemophilia Cohort Study

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Virus threshold determines disease in SIVsmmPBj14-infected macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Studies in subjects with long-term nonprogressive human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Isolation and partial characterization of an HIV-related virus occurring naturally in chimpanzees in Gabon

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Viral burden and disease progression in rhesus monkeys infected with chimeric simian-human immunodeficiency viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Understanding the origins of AIDS viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Cross-species transmission and recombination of ‘AIDS’ viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Generation of a chimeric human and simian immunodeficiency virus infectious to monkey peripheral blood mononuclear cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Infection and pathogenicity of chimeric simian-human immunodeficiency viruses in macaques: determinants of high virus loads and CD4 cell killing

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Live, attenuated simian immunodeficiency virus vaccines elicit potent resistance against a challenge with a human immunodeficiency virus type 1 chimeric virus.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

A highly pathogenic simian/human immunodeficiency virus with genetic changes in cynomolgus monkey

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Simian immunodeficiency virus disease course is predicted by the extent of virus replication during primary infection.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Plasma SIV RNA viral load determination by real-time quantification of product generation in reverse transcriptase-polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl) adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Effects of (R)-9-(2-phosphonylmethoxypropyl)adenine monotherapy on chronic SIV infection in macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

G protein-coupled receptors in HIV and SIV entry: new perspectives on lentivirus-host interactions and on the utility of animal models

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

The role of a stromal cell-derived factor-1 chemokine gene variant in the clinical course of HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Administration of 9-[2-(phosphonomethoxy)propyl]adenine (PMPA) for prevention of perinatal simian immunodeficiency virus infection in rhesus macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Control mechanisms of virus replication in naturally SIVsmm infected mangabeys and experimentally infected macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Immunological and virological studies of natural SIV infection of disease-resistant nonhuman primates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Early postinfection antiviral treatment reduces viral load and prevents CD4+ cell decline in HIV type 2-infected macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Plasma viremia in macaques infected with simian immunodeficiency virus: plasma viral load early in infection predicts survival.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Viral dynamics in human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

Simian immunodeficiency virus/delta-induced immunodeficiency disease in rhesus monkeys: relation of antibody response and antigenemia

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949034-4

7 January 2021

10.1016/S1054-3589(00)49034-4

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11013771