Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer. (Q34035601)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093899%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer (English)

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10 November 2019

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1

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10 November 2019

Robert J C Steele

8

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10 November 2019

C Wolf

9

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10 November 2019

author name string

Francis A Carey

2

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10 November 2019

Julie Beattie

3

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10 November 2019

Murray J V Wilkie

4

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10 November 2019

Tracy J Lightfoot

5

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10 November 2019

Jonathan Coxhead

6

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10 November 2019

R Colin Garner

7

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10 November 2019

language of work or name

English

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publication date

1 July 2002

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Proceedings of the National Academy of Sciences of the United States of America

10 November 2019

published in

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10 November 2019

volume

99

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10 November 2019

page(s)

9433-9438

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10 November 2019

issue

14

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

10 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

ABC of colorectal cancer: Epidemiology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Gain-of-function mutations in the tumor suppressor gene p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Twenty years of p53 research: structural and functional aspects of the p53 protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

p53 and human cancer: the first ten thousand mutations.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Colorectal cancer: molecules and populations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Loss of beta-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Incidence of hereditary non-polyposis colorectal cancer in a population-based study of 1137 consecutive cases of colorectal cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Mutations predisposing to hereditary nonpolyposis colorectal cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

p53, the cellular gatekeeper for growth and division

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Lessons from hereditary colorectal cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

APC mutations in colorectal tumors with mismatch repair deficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Clinical implications of the p53 tumor-suppressor gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

The role of the adenomatous polyposis coli (APC) gene in human cancers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Cancer in migrants to Australia: extending the descriptive epidemiological data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Localization of the gene for familial adenomatous polyposis on chromosome 5.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Genetic alterations during colorectal-tumor development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

ras oncogenes in human cancer: a review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

A genetic model for colorectal tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Identification and characterization of the familial adenomatous polyposis coli gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

APC mutations occur early during colorectal tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123158

K-ras mutations in putative preneoplastic lesions in human colon

29 October 2018

1 reference

12 December 2020

Screening for colorectal cancer

1 reference

12 December 2020

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis

1 reference

12 December 2020

Pharmacological rescue of mutant p53 conformation and function

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.122612899

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093899%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093899%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference