TCR-mediated ThPOK induction promotes development of mature (CD24-) gammadelta thymocytes. (Q34021127)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20551904%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

TCR-mediated ThPOK induction promotes development of mature (CD24-) gammadelta thymocytes (English)

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5 February 2020

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6

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5 February 2020

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Dietmar J Kappes

1 reference

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5 February 2020

author name string

Kyewon Park

1

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5 February 2020

Xi He

2

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5 February 2020

Hyung-Ok Lee

3

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5 February 2020

Xiang Hua

4

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5 February 2020

Yi Li

5

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5 February 2020

language of work or name

English

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publication date

15 June 2010

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5 February 2020

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5 February 2020

volume

29

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5 February 2020

issue

14

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5 February 2020

page(s)

2329-2341

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Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection

5 February 2020

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Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism

5 July 2018

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Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.

5 July 2018

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Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent

5 July 2018

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ThPOK derepression is required for robust CD8 T cell responses to viral infection

5 July 2018

1 reference

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TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity

5 July 2018

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Id3 restricts the developmental potential of gamma delta lineage during thymopoiesis

5 July 2018

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Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers.

5 July 2018

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Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma

5 July 2018

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An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells

5 July 2018

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The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development

5 July 2018

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T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis.

5 July 2018

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On the road: progress in finding the unique pathway of invariant NKT cell differentiation

5 July 2018

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CD4/CD8 lineage commitment: light at the end of the tunnel?

5 July 2018

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Recent insights into the signals that control alphabeta/gammadelta-lineage fate.

5 July 2018

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The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.

5 July 2018

1 reference

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An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors

5 July 2018

1 reference

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Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade

5 July 2018

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Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene

5 July 2018

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The regulation of CD4 and CD8 coreceptor gene expression during T cell development

5 July 2018

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HD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) T cells

5 July 2018

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5 July 2018

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Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors.

5 July 2018

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T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells.

5 July 2018

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5 July 2018

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A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire.

5 July 2018

1 reference

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Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage.

21 January 2018

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CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.

21 January 2018

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Regulation of lineage commitment distinct from positive selection.

21 January 2018

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Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.113

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.113

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.113

Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals.

21 January 2018

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Tissue-specific segregation of TCRgamma delta+ NKT cells according to phenotype TCR repertoire and activation status: parallels with TCR alphabeta+NKT cells

21 January 2018

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12 December 2020

Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages

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12 December 2020

Analysis of recent thymic emigrants with subset- and maturity-related markers

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12 December 2020

Emigration of selected subsets of gamma delta + T cells from the adult murine thymus

1 reference

12 December 2020

Development of gamma delta T cells in the adult murine thymus

1 reference

12 December 2020

The homogeneity of the TCRδ repertoire expressed by the Thy-1dull γ δ T cell population is due to cellular selection

2 references

12 December 2020

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.113

7 January 2021

inferred from DOI database lookup

Signals transduced by CD3epsilon, but not by surface pre-TCR complexes, are able to induce maturation of an early thymic lymphoma in vitro

1 reference

12 December 2020

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

1 reference

12 December 2020

TCR signal strength influences alphabeta/gammadelta lineage fate

1 reference

12 December 2020

CCR6 and NK1.1 distinguish between IL-17A and IFN-γ-producing γδ effector T cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2010.113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20551904%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20551904%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20551904%20AND%20SRC:MED&resulttype=core&format=json