Intranasal delivery of neurotrophic factors BDNF, CNTF, EPO, and NT-4 to the CNS. (Q34019665)

30 July 2017

Intranasal delivery of neurotrophic factors BDNF, CNTF, EPO, and NT-4 to the CNS. (English)

1 reference

30 July 2017

Sandra R Alcalá-Barraza

1

1 reference

30 July 2017

Michael S Lee

2

1 reference

30 July 2017

Leah R Hanson

3

1 reference

30 July 2017

Abby A McDonald

4

1 reference

30 July 2017

William H Frey

5

1 reference

30 July 2017

Linda K McLoon

6

1 reference

30 July 2017

language of work or name

1 reference

1 April 2010

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Journal of Drug Targeting

30 July 2017

1 reference

30 July 2017

18

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30 July 2017

179-190

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30 July 2017

3

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Intranasal insulin ameliorates experimental diabetic neuropathy

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

New insights into brain BDNF function in normal aging and Alzheimer disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Exploiting endogenous anti-apoptotic proteins for novel therapeutic strategies in cerebral ischemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Delivery of interferon-beta to the monkey nervous system following intranasal administration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Erythropoietin reduces cisplatin-induced neurotoxicity without impairment of cytotoxic effects against tumor cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Neuroprotection by erythropoietin administration after experimental traumatic brain injury

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Intranasal insulin to improve memory function in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Can nasal drug delivery bypass the blood-brain barrier?: questioning the direct transport theory

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Role of brain-derived neurotrophic factor in Huntington's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Cellular mechanisms associated with spontaneous and ciliary neurotrophic factor-cAMP-induced survival and axonal regeneration of adult retinal ganglion cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Manipulating central nervous mechanisms of food intake and body weight regulation by intranasal administration of neuropeptides in man.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Intranasal insulin improves memory in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Is nose-to-brain transport of drugs in man a reality?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Drug delivery to the central nervous system: a review

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Signaling of Cell Death and Cell Survival Following Focal Cerebral Ischemia: Life and Death Struggle in the Penumbra

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Delivery of Nerve Growth Factor to the Brain via the Olfactory Pathway.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Sniffing neuropeptides: a transnasal approach to the human brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

In vivo evidence that erythropoietin protects neurons from ischemic damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Cellular delivery of human CNTF prevents motor and cognitive dysfunction in a rodent model of Huntington's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Brain potential changes after intranasal vs. intravenous administration of vasopressin: evidence for a direct nose-brain pathway for peptide effects in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

BDNF protection of basal forebrain cholinergic neurons after axotomy: complete protection of p75NGFR-positive cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Ciliary neurotrophic factor prevents retrograde neuronal death in the adult central nervous system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

CNTF promotes the survival of neonatal rat corticospinal neurons in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Recombinant human ciliary neurotrophic factor alters the threshold of hippocampal pyramidal neuron sensitivity to excitotoxin damage: synergistic effects of monosialogangliosides.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Preparation of iodine-125-labeled insulin for radioimmunoassay: comparison of lactoperoxidase and chloramine-T iodination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis.

28 July 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

CNTF+BDNF treatment and neuroprotective pathways in the rd1 mouse retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Low and dysregulated BDNF secretion from immune cells of MS patients is related to reduced neuroprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Differential sensitivity of men and women to anorexigenic and memory-improving effects of intranasal insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Adeno-associated viral vector-mediated neurotrophin gene transfer in the injured adult rat spinal cord improves hind-limb function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Erythropoietin reduces epileptogenic processes following status epilepticus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Combined therapy with methylprednisolone and erythropoietin in a model of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Stroke damage in mice after knocking the neutrophin-4 gene into the brain-derived neurotrophic factor locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

BMP4 and CNTF are neuroprotective and suppress damage-induced proliferation of Müller glia in the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Intranasal insulin prevents cognitive decline, cerebral atrophy and white matter changes in murine type I diabetic encephalopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Obese men respond to cognitive but not to catabolic brain insulin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Ciliary neurotrophic factor protects rat retina cells in vitro and in vivo via PI3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Coexpression of neurotrophins and their receptors in neurons of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Nerve growth factor expressed in the medial septum following in vivo gene delivery using a recombinant adeno-associated viral vector protects cholinergic neurons from fimbria-fornix lesion-induced degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Direct access of drugs to the human brain after intranasal drug administration?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Transducible P11-CNTF rescues the learning and memory impairments induced by amyloid-beta peptide in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Effects of intranasal insulin on cognition in memory-impaired older adults: modulation by APOE genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Intranasal insulin improves cognition and modulates beta-amyloid in early AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Hippocampal vulnerability following traumatic brain injury: a potential role for neurotrophin-4/5 in pyramidal cell neuroprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Analysis of neurotrophin/receptor interactions with a gD-flag-modified quantitative kinase receptor activation (gD.KIRA) enzyme-linked immunosorbent assay

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Neuroprotection of brain-derived neurotrophic factor against hypoxic injury in vitro requires activation of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

The role of brain-derived neurotrophic factor in transient forebrain ischemia in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Nose-to-brain delivery of TS-002, prostaglandin D2 analogue.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

The brain targeting efficiency following nasally applied MPEG-PLA nanoparticles in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611860903318134

Iodination of soluble and membrane-bound proteins

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Stability of housekeeping gene expression in the rat retina during exposure to cyclic hyperoxia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Erythropoietin and erythropoietin receptor in human ischemic/hypoxic brain.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

BDNF and NT4/5 promote survival and neurite outgrowth of pontocerebellar mossy fiber neurons.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Expression of ciliary neurotrophic factor receptor-alpha messenger RNA in neonatal and adult rat brain: an in situ hybridization study.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

Neurotrophins affect survival and neuritogenesis by adult injured auditory neurons in vitro.

29 October 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732751

29 October 2018

https://api.crossref.org/works/10.3109%2F10611860903318134

Intranasal recombinant human erythropoietin protects rats against focal cerebral ischemia

21 January 2018

1 reference

12 December 2020

Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity

1 reference

12 December 2020

Localization of neurotrophin receptors in olfactory epithelium and bulb

1 reference

12 December 2020

Adenovirus-mediated expression of ciliary neurotrophic factor (CNTF) rescues axotomized rat retinal ganglion cells but does not support axonal regeneration in vivo

1 reference

12 December 2020

The window of opportunity for treatment of focal cerebral ischemic damage with noninvasive intranasal insulin-like growth factor-I in rats

1 reference

12 December 2020

Quantitative analysis of the olfactory pathway for drug delivery to the brain

1 reference

12 December 2020

Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion

1 reference

12 December 2020

Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration

1 reference

12 December 2020

10.3109/10611860903318134

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference