ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2. (Q34017928)

30 July 2017

ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2. (English)

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30 July 2017

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2

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1 June 2020

author name string

Ram Mohan Ram Kumar

1

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1 June 2020

Bernhard Robl

3

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1 June 2020

Walter Born

4

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1 June 2020

Bruno Fuchs

5

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1 June 2020

language of work or name

English

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publication date

1 August 2014

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30 July 2017

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1 June 2020

volume

14

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1 June 2020

page(s)

559

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https://scigraph.springernature.com/pub.10.1186/1471-2407-14-559

1 June 2020

exact match

0 references

cites work

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ΔNp63 promotes pediatric neuroblastoma and osteosarcoma by regulating tumor angiogenesis

28 July 2018

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Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma

28 July 2018

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DeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistance

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ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation

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ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis

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LacZ transgene expression in the subcutaneous Dunn/LM8 osteosarcoma mouse model allows for the identification of micrometastasis

28 July 2018

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TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

28 July 2018

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Overexpression of ΔNp63α induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway

28 July 2018

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Smoothened as a new therapeutic target for human osteosarcoma

28 July 2018

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Identification and functional characterization of two new transcriptional variants of the human p63 gene

28 July 2018

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p63 contributes to cell invasion and migration in squamous cell carcinoma of the head and neck.

28 July 2018

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28 July 2018

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New p63 targets in keratinocytes identified by a genome-wide approach.

28 July 2018

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Osteosarcoma: anatomic and histologic variants

28 July 2018

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p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

28 July 2018

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Establishment and characterization of cell sublines with high and low metastatic potential derived from human osteosarcoma

28 July 2018

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DeltaNp63alpha up-regulates the Hsp70 gene in human cancer

28 July 2018

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deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes

28 July 2018

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A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

28 July 2018

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28 July 2018

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28 July 2018

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21 January 2018

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21 January 2018

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21 January 2018

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p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes

21 January 2018

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Role of GLI2 in the growth of human osteosarcoma.

21 January 2018

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Inhibition of the Wnt-β-catenin and Notch signaling pathways sensitizes osteosarcoma cells to chemotherapy.

21 January 2018

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DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development

21 January 2018

1 reference

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Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25085524

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12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-14-559

1 reference

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Dimensions Publication ID

1 June 2020

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1 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25085524%20AND%20SRC:MED&resulttype=core&format=json