Sex-dependent role of glucocorticoids and androgens in the pathophysiology of human obesity (Q34014004)

30 July 2017

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title

Sex-dependent role of glucocorticoids and androgens in the pathophysiology of human obesity (English)

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30 July 2017

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V Vicennati

2

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author name string

R Pasquali

series ordinal

1

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30 July 2017

A Gambineri

series ordinal

3

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30 July 2017

U Pagotto

series ordinal

4

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30 July 2017

language of work or name

English

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publication date

7 October 2008

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International Journal of Obesity

30 July 2017

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30 July 2017

32

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30 July 2017

12

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30 July 2017

1764-1779

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https://scigraph.springernature.com/pub.10.1038/ijo.2008.129

30 July 2017

0 references

1 reference

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The obesity pandemic: where have we been and where are we going?

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Role of stress in the pathogenesis of the metabolic syndrome

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Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation

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The anti-inflammatory and potential anti-atherogenic effect of insulin: a new paradigm

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Obesity and androgens: facts and perspectives

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Do stress reactions cause abdominal obesity and comorbidities?

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The hypothalamic-pituitary-adrenal axis activity in obesity and the metabolic syndrome

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Functional cross-talk between the hypothalamic-pituitary-gonadal and -adrenal axes

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Sex difference in the relationship between the hypothalamic-pituitary-adrenal axis and sex hormones in obesity

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21 January 2018

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The abdominal obesity phenotype and insulin resistance are associated with abnormalities of the hypothalamic-pituitary-adrenal axis in humans

21 January 2018

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11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response

21 January 2018

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Glucocorticoids and cardiovascular disease

21 January 2018

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Glucocorticoids: exemplars of multi-tasking

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Minireview: glucocorticoids--food intake, abdominal obesity, and wealthy nations in 2004.

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The biology of human sex differences

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The obesity epidemic, metabolic syndrome and future prevention strategies

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A comprehensive view of sex-specific issues related to cardiovascular disease

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The metabolic syndrome

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Prevalence of the metabolic syndrome in US populations

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Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

21 January 2018

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Gender differences in the metabolic syndrome and their role for cardiovascular disease.

21 January 2018

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Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome

21 January 2018

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Cardiovascular risk factors and metabolic control in type 2 diabetic subjects attending outpatient clinics in Italy: the SFIDA (survey of risk factors in Italian diabetic subjects by AMD) study

21 January 2018

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WHO and ATPIII proposals for the definition of the metabolic syndrome in patients with Type 2 diabetes

21 January 2018

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Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study

21 January 2018

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Association of total and central obesity with mortality in postmenopausal women with coronary heart disease

21 January 2018

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Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men.

21 January 2018

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Weight gain as a risk factor for clinical diabetes mellitus in women

21 January 2018

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Pathophysiology of modulation of local glucocorticoid levels by 11beta-hydroxysteroid dehydrogenases

21 January 2018

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A transgenic model of visceral obesity and the metabolic syndrome

21 January 2018

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11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

21 January 2018

1 reference

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Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice

21 January 2018

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On the regulation of sex-hormone-binding globulin--a challenge of an old dogma and outlines of an alternative mechanism

21 January 2018

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Sex steroid hormones, sex hormone-binding globulin, and obesity in men and women

21 January 2018

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Mild Hypogonadotropic hypogonadism in obese men.

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Reduced testosterone and adrenal C19 steroid levels in obese men.

21 January 2018

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Effect of obesity and body fat distribution on sex hormones and insulin in men.

21 January 2018

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Stress and the metabolic syndrome: an interesting but enigmatic association

21 January 2018

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Protective and damaging effects of stress mediators

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A healthy body in a healthy mind--and vice versa--the damaging power of "uncontrollable" stress.

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Visceral obesity: a "civilization syndrome".

21 January 2018

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Mental distress, obesity and body fat distribution in middle-aged men.

21 January 2018

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Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging

21 January 2018

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Combinations of biomarkers predictive of later life mortality

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Effects of stress on reproduction in non-rodent mammals: the role of glucocorticoids and sex differences

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Effect of Stress on the Activity of the Hypothalamic-Pituitary-Gonadal Axis: Peripheral and Central Mechanisms1

21 January 2018

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Sex differences in sensitivity of the hypothalamic-pituitary-adrenal axis.

21 January 2018

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The effect of repeated human corticotropin-releasing hormone administration on dexamethasone-suppressed pituitary-adrenocortical activity in healthy subjects.

21 January 2018

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The hypothalamic-pituitary-adrenal axis in obese women with different patterns of body fat distribution.

21 January 2018

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21 January 2018

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21 January 2018

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Menstrual abnormalities in women with Cushing's disease are correlated with hypercortisolemia rather than raised circulating androgen levels.

21 January 2018

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The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes

21 January 2018

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Banting lecture 1988. Role of insulin resistance in human disease

21 January 2018

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Metabolic effects of the nocturnal rise in cortisol on carbohydrate metabolism in normal humans

21 January 2018

1 reference

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Gender differences in the associations between cortisol and insulin in healthy subjects.

21 January 2018

1 reference

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Cortisol and the metabolic syndrome in South Asians

21 January 2018

1 reference

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Reduction in allostatic load in older adults is associated with lower all-cause mortality risk: MacArthur studies of successful aging

21 January 2018

1 reference

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Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study.

21 January 2018

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Cortisol, testosterone, and coronary heart disease: prospective evidence from the Caerphilly study

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Preliminary results on mood state, salivary testosterone:cortisol ratio and team performance in a professional soccer team

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Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure.

21 January 2018

1 reference

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Association of coronary artery disease with glucocorticoid receptor N363S variant

21 January 2018

1 reference

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Androgens and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

Androgens, insulin resistance and vascular disease in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysis

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Association between plasma total testosterone and cardiovascular risk factors in healthy adult men: The Telecom Study.

21 January 2018

1 reference

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Endogenous sex hormones and metabolic syndrome in aging men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

Sex differences in the association of endogenous sex hormone levels and glucose tolerance status in older men and women

21 January 2018

1 reference

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Testosterone for secondary prevention in men with ischaemic heart disease?

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Insulin-Lowering Agents in the Management of Polycystic Ovary Syndrome

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Imprinting of female offspring with testosterone results in insulin resistance and changes in body fat distribution at adult age in rats

21 January 2018

1 reference

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Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis

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1 reference

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Treatment with flutamide, metformin, and their combination added to a hypocaloric diet in overweight-obese women with polycystic ovary syndrome: a randomized, 12-month, placebo-controlled study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

Glucose intolerance in a large cohort of mediterranean women with polycystic ovary syndrome: phenotype and associated factors.

21 January 2018

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Polycystic ovary syndrome and cardiovascular disease: a premature association?

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1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

Postmenopausal women with a history of irregular menses and elevated androgen measurements at high risk for worsening cardiovascular event-free survival: results from the National Institutes of Health--National Heart, Lung, and Blood Institute spons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

Prospective study of endogenous sex hormones and fatal cardiovascular disease in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

Plasma sex steroid hormones and risk of developing type 2 diabetes in women: a prospective study

21 January 2018

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Obesity and the polycystic ovary syndrome

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1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

Novel polymorphisms in the neuropeptide-Y Y5 receptor associated with obesity in Pima Indians

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Elevated production and metabolic clearance rates of androgens in morbidly obese women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

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Androgen-estrogen metabolism in women with upper body versus lower body obesity

1 reference

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Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity

1 reference

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Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

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Metabolic syndrome in American Indians

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Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome

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Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report

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Indexes of abdominal adiposity in patients with type 2 diabetes

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Neuroendocrine abnormalities in visceral obesity

1 reference

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Glucocorticoid hormone binding to human adipose tissue

1 reference

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Maintenance of normal circulating levels of delta 4-androstenedione and dehydroepiandrosterone in simple obesity despite increased metabolic clearance rates: evidence for a servo-control mechanism

1 reference

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7 January 2021

Characterization of obese women with reduced sex hormone-binding globulin concentrations

1 reference

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7 January 2021

Relationship of androgenic activity to body fat topography, fat cell morphology, and metabolic aberrations in premenopausal women.

1 reference

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7 January 2021

Catecholaminergic modulation of corticotropin-releasing factor and adrenocorticotropin secretion

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The inhibitory effect of testosterone on hypothalamic-pituitary-adrenal responses to stress is mediated by the medial preoptic area.

1 reference

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Effects of Gonadectomy on Glucocorticoid Metabolism in Obese Zucker Rats

1 reference

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Normal and abnormal function of the hypothalamic-pituitary-adrenocortical system in man.

1 reference

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ACTH and cortisol response to combined corticotropin releasing hormone-arginine vasopressin stimulation in obese males and its relationship to body weight, fat distribution and parameters of the metabolic syndrome

1 reference

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Sex differences in adrenocortical structure and function. XXVII. The effect of ether stress on ACTH and corticosterone in intact, gonadectomized, and testosterone- or estradiol-replaced rats.

1 reference

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Exposure to ovarian steroids elicits a female pattern of plasma cortisol levels in castrated male macaques

1 reference

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The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis

1 reference

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Corticotropin-releasing hormone inhibits gonadotropin secretion in the ovariectomized rhesus monkey

1 reference

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7 January 2021

production rates of testosterone in patients with Cushing's syndrome

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

7 January 2021

Banting lecture 1988. Role of insulin resistance in human disease

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

7 January 2021

The relationship of blood pressure with glucose, insulin, heart rate, free fatty acids and plasma cortisol levels according to degree of obesity in middle-aged men.

1 reference

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Increased glucocorticoid activity in men with cardiovascular risk factors

1 reference

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High anticipatory stress plasma cortisol levels and sensitivity to glucocorticoids predict severity of coronary artery disease in subjects undergoing coronary angiography

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Associations of obesity markers, insulin, and sex hormones with HDL-cholesterol levels in Turkish and German individuals

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Low serum testosterone level as a predictor of increased visceral fat in Japanese-American men

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Effects of testosterone suppression in young men by the gonadotropin releasing hormone antagonist cetrorelix on plasma lipids, lipolytic enzymes, lipid transfer proteins, insulin, and leptin.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

7 January 2021

Low sex-hormone-binding globulin concentration as independent risk factor for development of NIDDM. 12-yr follow-up of population study of women in Gothenburg, Sweden.

1 reference

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Role of changes in dietary habits in polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.129

7 January 2021

Identifiers

DOI

10.1038/IJO.2008.129

1 reference

Dimensions Publication ID

30 July 2017

1010371334

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Fatcat ID

release_zvdjbfhljra3ngqfpjdzrl7nj4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zvdjbfhljra3ngqfpjdzrl7nj4

24 November 2022

mapped directly with Wikidata item

1 reference