A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication (Q34013854)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Chi V. Dang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

10

Gregg L Semenza

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Maimon E Hubbi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Kshitiz

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Daniele M Gilkes

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Sergio Rey

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Carmen C Wong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Weibo Luo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Andre Levchenko

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

publication date

12 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

ra10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation

23 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

MCM proteins are negative regulators of hypoxia-inducible factor 1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Development of HIF-1 inhibitors for cancer therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Regulation of oxygen homeostasis by hypoxia-inducible factor 1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

ATM activation and signaling under hypoxic conditions.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Reactive oxygen species-mediated cyclin D1 degradation mediates tumor growth retardation in hypoxia, independently of p21cip1 and hypoxia-inducible factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Biology of hypoxia-inducible factor-2alpha in development and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Cell cycle regulation of DNA replication.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Non-transcriptional control of DNA replication by c-Myc

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Self-assembling protein microarrays

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Hypoxia links ATR and p53 through replication arrest

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Analysis of Cdc6 function in the assembly of mammalian prereplication complexes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124626

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

28 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

HIF-1 or HIF-2 induction is sufficient to achieve cell cycle arrest in NIH3T3 mouse fibroblasts independent from hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

Uninterrupted MCM2-7 function required for DNA replication fork progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

CDC6: from DNA replication to cell cycle checkpoints and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003417

Hypoxia inhibits G1/S transition through regulation of p27 expression

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23405012

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A model for the computer analysis of synchronous DNA distributions obtained by flow cytometry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23405012

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23405012

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCISIGNAL.2003417

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23405012%20AND%20SRC:MED&resulttype=core&format=json