The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes (Q34003799)

30 July 2017

The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes (English)

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30 July 2017

2

Marcin Ratajewski

1 reference

30 July 2017

6

Lukasz Pulaski

1 reference

30 July 2017

Hugues de Boussac

1

1 reference

30 July 2017

Iwona Sachrajda

3

1 reference

30 July 2017

Gabriella Köblös

4

1 reference

30 July 2017

Attila Tordai

5

1 reference

30 July 2017

László Buday

7

1 reference

30 July 2017

András Váradi

8

1 reference

30 July 2017

Tamás Arányi

9

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30 July 2017

language of work or name

English

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publication date

12 May 2010

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Journal of Biological Chemistry

30 July 2017

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30 July 2017

285

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30 July 2017

30

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30 July 2017

22800-22808

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Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

The R1141X loss-of-function mutation of the ABCC6 gene is a strong genetic risk factor for coronary artery disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

The hepatocyte growth factor/c-Met signaling pathway as a therapeutic target to inhibit angiogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Pseudoxanthoma elasticum: clinical phenotypes, molecular genetics and putative pathomechanisms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Pseudoxanthoma elasticum is a metabolic disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

External cell control polymerase chain reaction: replacing internal standards with an unbiased strategy for quantitative polymerase chain reaction normalization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Phosphorylation of a conserved serine in the deoxyribonucleic acid binding domain of nuclear receptors alters intracellular localization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

DNA methylation and Sp1 binding determine the tissue-specific transcriptional activity of the mouse Abcc6 promoter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

28 July 2018

The BiSearch web server

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

HNF4alpha and NF-E2 are key transcriptional regulators of the murine Abcc6 gene expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Mitogen-activated protein kinase-mediated disruption of enhancer-promoter communication inhibits hepatocyte nuclear factor 4alpha expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Hepatocyte nuclear factor (HNF) 1 and HNF4 mediate hepatic multidrug resistance protein 2 up-regulation during hepatitis C virus gene expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Identification of a DNA methylation-dependent activator sequence in the pseudoxanthoma elasticum gene, ABCC6.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Control of pancreas and liver gene expression by HNF transcription factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Frequent mutation in the ABCC6 gene (R1141X) is associated with a strong increase in the prevalence of coronary artery disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Mutations in ABCC6 cause pseudoxanthoma elasticum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906271

Pseudoxanthoma elasticum: genetic diagnostic markers

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

A novel Q378X mutation exists in the transmembrane transporter protein ABCC6 and its pseudogene: implications for mutation analysis in pseudoxanthoma elasticum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Role of serum fetuin-A, a major inhibitor of systemic calcification, in pseudoxanthoma elasticum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

The human pseudoxanthoma elasticum gene ABCC6 is transcriptionally regulated by PLAG family transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Transcriptional regulation and characterization of the promoter region of the human ABCC6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Liver-specific enhancer in ABCC6 promoter-Functional evidence from natural polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Protein kinase C modulates negatively the hepatocyte growth factor-induced migration, integrin expression and phosphatidylinositol 3-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

A cellular gene up-regulated by hepatitis B virus-encoded X antigen promotes hepatocellular growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

c-Met signalling: spatio-temporal decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Protein kinase C isoforms: Multi-functional regulators of cell life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Mitogen-activated protein kinase regulates transcription of the ApoCIII gene. Involvement of the orphan nuclear receptor HNF4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Oxidative stress in fibroblasts from patients with pseudoxanthoma elasticum: possible role in the pathogenesis of clinical manifestations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Does the absence of ABCC6 (multidrug resistance protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Integration of MAP kinase signal transduction pathways at the serum response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

Phosphatidylinositol 3-kinase Contributes to Erk1/Erk2 MAP Kinase Activation Associated with Hepatocyte Growth Factor-induced Cell Scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.105593

The local calcification inhibitor matrix Gla protein in pseudoxanthoma elasticum

21 January 2018

1 reference

12 December 2020

How segmental duplications shape our genome: recent evolution of ABCC6 and PKD1 Mendelian disease genes

1 reference

12 December 2020

Identification of heterozygote carriers in families with a recessive form of pseudoxanthoma elasticum (PXE)

1 reference

12 December 2020

Acquired Pseudoxanthoma elasticum-like syndrome in beta-thalassaemia patients

1 reference

12 December 2020

Expression of the human ABCC6 gene is induced by retinoids through the retinoid X receptor

1 reference

12 December 2020

Mutational analysis of theABCC6 gene and the proximalABCC6 gene promoter in German patients with pseudoxanthoma elasticum (PXE)

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.105593

1 reference

30 July 2017

1 reference

30 July 2017

1 reference