Cross-sector review of drivers and available 3Rs approaches for acute systemic toxicity testing. (Q34000801)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

review article

2 references

2 October 2023

Cross-sector review of drivers and available 3Rs approaches for acute systemic toxicity testing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

19 September 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

2

Sally Robinson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

7

Magda Chlebus

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

4

Stuart Creton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

3

Tom Holmes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

5

Pilar Prieto

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

6

Julia Scheel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

publication date

19 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 August 2010

1 reference

2 October 2023

Toxicological Sciences

3 references

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

2 October 2023

116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

page(s)

382-396

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial

2 February 2020

copyright license

2 references

19 September 2019

2 October 2023

Acute toxicity testing of chemicals-Opportunities to avoid redundant testing and use alternative approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905404

ECVAM's ongoing activities in the area of acute oral toxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905404

A European pharmaceutical company initiative challenging the regulatory requirement for acute toxicity studies in pharmaceutical drug development.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905404

Guidance on setting of acute reference dose (ARfD) for pesticides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905404

Acute systemic toxicity--prospects for tiered testing strategies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905404

Decision of the Organization for Economic Co-operation and Development Council concerning the Mutual Acceptance of Data in the Assessment of Chemicals, adopted by the Council at its 535th meeting on 12 May 1981.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905404

MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905404

A new approach to practical acute toxicity testing

29 October 2018

1 reference

12 December 2020

Strategies to replace in vivo acute systemic toxicity testing. The report and recommendations of ECVAM Workshop 50

1 reference

12 December 2020

A new approach to the classification of substances and preparations on the basis of their acute toxicity. A report by the British Toxicology Society working party on toxicity

1 reference

12 December 2020

Significance of the LD50-test for the toxicological evaluation of chemical substances

1 reference

12 December 2020

Are acute toxicity studies required to support overdose for new medicines?

1 reference

12 December 2020

The role of the European Chemicals Bureau in promoting the regulatory use of (Q)SAR methods†

1 reference

12 December 2020

Estimation of acute oral toxicity using the No Observed Adverse Effect Level (NOAEL) from the 28 day repeated dose toxicity studies in rats

1 reference

12 December 2020

Identifiers

DOI

10.1093/TOXSCI/KFQ143

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484382%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

20484382

1 reference