Enhanced Th1 and dampened Th2 responses synergize to inhibit acute granulomatous and fibrotic responses in murine schistosomiasis mansoni. (Q34000581)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10024559%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Enhanced Th1 and dampened Th2 responses synergize to inhibit acute granulomatous and fibrotic responses in murine schistosomiasis mansoni (English)

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10 November 2019

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D L Boros

1

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10 November 2019

J R Whitfield

series ordinal

2

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10 November 2019

language of work or name

English

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publication date

1 March 1999

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10 November 2019

published in

Infection and Immunity

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10 November 2019

volume

67

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10 November 2019

page(s)

1187-1193

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10 November 2019

issue

3

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Schistosoma mansoni egg-induced early IL-4 production is dependent upon IL-5 and eosinophils

10 November 2019

cites work

1 reference

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Schistosomiasis. Infection versus disease and hypersensitivity versus immunity.

5 July 2018

1 reference

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Cloning of TH0- and TH2-type helper lymphocytes from liver granulomas of Schistosoma mansoni-infected mice.

5 July 2018

1 reference

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Properties and functions of interleukin-10.

5 July 2018

1 reference

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Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice

5 July 2018

1 reference

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The role of cytokines in the formation of the schistosome egg granuloma

5 July 2018

1 reference

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Antibodies to interleukin 12 abrogate established experimental colitis in mice

5 July 2018

1 reference

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Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

5 July 2018

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Cytokine regulation of granuloma formation in schistosomiasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Conditions affecting the accuracy of potassium hydroxide digestion techniques for counting Schistosoma mansoni eggs in tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Anti-L3T4 antibody treatment suppresses hepatic granuloma formation and abrogates antigen-induced interleukin-2 production in Schistosoma mansoni infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

IL-4 directs the development of Th2-like helper effectors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Utilization of fractionated soluble egg antigens reveals selectively modulated granulomatous and lymphokine responses during murine schistosomiasis mansoni

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Tumour necrosis factor alpha restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

CD4+ Th2 response induced by Schistosoma mansoni eggs develops rapidly, through an early, transient, Th0-like stage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Altered Schistosome Granuloma Formation in Nude Mice *

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Analysis of granuloma formation in double cytokine-deficient mice reveals a central role for IL-10 in polarizing both T helper cell 1- and T helper cell 2-type cytokine responses in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Cross-regulatory role of interferon-gamma (IFN-gamma), IL-4 and IL-10 in schistosome egg granuloma formation: in vivo regulation of Th activity and inflammation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Schistosoma mansoni egg antigens and hepatocyte damage in infected T cell-deprived mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96445

Delayed hypersensitivity granuloma formation around Schistosoma mansoni eggs in vitro. I. Definition of the model

29 October 2018

1 reference

12 December 2020

Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response.

1 reference

12 December 2020

Characterization of granuloma T lymphocyte function from Schistosoma mansoni-infected mice

1 reference

12 December 2020

Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni

1 reference

12 December 2020

The cell-mediated response to schistosomal antigens at the clonal level. III. Identification of soluble egg antigens recognized by cloned specific granulomagenic murine CD4+ Th1-type lymphocytes

1 reference

12 December 2020

Lymphokine regulation of granuloma formation in murine schistosomiasis mansoni

1 reference

12 December 2020

Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni

1 reference

12 December 2020

Lymphokine expression in granulomas of Schistosoma mansoni-infected mice

1 reference

12 December 2020

Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis

1 reference

12 December 2020

Regulation of T helper cell responses in experimental murine schistosomiasis by IL-10. Effect on expression of B7 and B7-2 costimulatory molecules by macrophages

1 reference

12 December 2020

IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-gamma

1 reference

12 December 2020

In situ analysis of cytokine responses in experimental murine schistosomiasis

1 reference

12 December 2020

An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection

1 reference

12 December 2020

Recombinant IL-10 and IL-10/Fc treatment down-regulate egg antigen-specific delayed hypersensitivity reactions and egg granuloma formation in schistosomiasis

1 reference

12 December 2020

A simplified method for the analysis of hydroxyproline in biological tissues

1 reference

12 December 2020

10.1128/IAI.67.3.1187-1193.1999

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1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10024559%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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