Total synthesis and evaluation of a key series of C5-substituted vinblastine derivatives (Q33990434)

30 July 2017

Total synthesis and evaluation of a key series of C5-substituted vinblastine derivatives (English)

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30 July 2017

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Porino Va

1

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30 July 2017

Erica L Campbell

series ordinal

2

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30 July 2017

William M Robertson

series ordinal

3

1 reference

30 July 2017

Dale L Boger

series ordinal

4

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30 July 2017

language of work or name

English

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publication date

1 June 2010

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Journal of the American Chemical Society

30 July 2017

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30 July 2017

132

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30 July 2017

8489-8495

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30 July 2017

24

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Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Synthesis and biological evaluation of C-12' substituted vinflunine derivatives

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Direct coupling of catharanthine and vindoline to provide vinblastine: total synthesis of (+)- and ent-(-)-vinblastine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Targeting multidrug resistance in cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Total synthesis of (-)- and ent-(+)-vindoline

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Total synthesis of natural (+)- [corrected] and ent-(-)-4-desacetoxy-6,7-dihydrovindorosine [corrected] and natural and ent-minovine: oxadiazole tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reaction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Stereocontrolled total synthesis of (+)-vincristine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Circumvention of P-GP MDR as a function of anthracycline lipophilicity and charge

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Inhibition of tubulin-microtubule polymerization by drugs of the Vinca alkaloid class

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Total synthesis of indole and dihydroindole alkaloids. IX. Studies on the synthesis of bisindole alkaloids in the vinblastine-vincristine series. The biogenetic approach

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Synthesis and structure-activity relationship studies of cytotoxic anhydrovinblastine amide derivatives.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Synthesis and SAR of vinca alkaloid analogues

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

N-Deformyl Vincristine a Bisalkaloid from Catharanthus roseus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Intramolecular diels-alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Structural basis for the regulation of tubulin by vinblastine

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Syntheses and biological evaluation of vinblastine congeners

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Intramolecular Diels-Alder and tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reactions of 1,3,4-oxadiazoles

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Stereocontrolled total synthesis of (+)-vinblastine

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Modifications in the "upper" velbenamine part of the Vinca alkaloids have major implications for tubulin interacting activities

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903230

Application of a modification of the Polonovski reaction to the synthesis of vinblastine-type alkaloids

29 October 2018

1 reference

12 December 2020

Total synthesis of (-)- and ent-(+)-vindorosine: tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition of 1,3,4-oxadiazoles

1 reference

12 December 2020

ALKALOIDS OF VINCA ROSEA LINN. (CATHARANTHUS ROSEUS G. DON). XXIV. VINASPINE, VINCATHICINE, ROVIDINE, DESACETYL VLB, AND VINAPHAMINE

1 reference

12 December 2020

Synthesis of (+)-vinblastine and its analogues

1 reference

12 December 2020

Alkaloids of Vinca rosea Linn. (Catharanthus roseus G. Don.). V. Preparation and characterization of alkaloids

1 reference

12 December 2020

Role of chance observations in chemotherapy: Vinca rosea

1 reference

12 December 2020

Structure-activity relationships of dimeric Catharanthus alkaloids. 1. Deacetyl vinblastine amide (vindesine) sulfate

1 reference

12 December 2020

Vinca alkaloids XXXV. Desacetoxyvinblastine a new minor alkaloid fromVinca rosea L. (Catharanthus roseus G. Don)

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12 December 2020

Identifiers

DOI

10.1021/JA1027748

1 reference

release_ov6fbuf5cnaj3f7jht5jmlwite

30 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ov6fbuf5cnaj3f7jht5jmlwite

24 November 2022

mapped directly with Wikidata item

PMCID

2903230

1 reference

30 July 2017

1 reference