Is there a therapeutic opportunity to either prevent or treat osteopenic disorders by inhibiting marrow adipogenesis? (Q33983147)

30 July 2017

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title

Is there a therapeutic opportunity to either prevent or treat osteopenic disorders by inhibiting marrow adipogenesis? (English)

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30 July 2017

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Nuttall ME

1

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PubMed ID

10913909

30 July 2017

Gimble JM

series ordinal

2

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30 July 2017

1 August 2000

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30 July 2017

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30 July 2017

27

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30 July 2017

177-184

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30 July 2017

2

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Cellular and molecular aspects of adipose tissue development

30 July 2017

1 reference

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7 January 2021

Characterization of cells with high alkaline phosphatase activity derived from human bone and marrow: preliminary assessment of their osteogenicity

1 reference

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7 January 2021

Bone marrow adipose tissue: Response to acute starvation

1 reference

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7 January 2021

1,25-Dihydroxyvitamin D3 and human bone-derived cells in vitro: effects on alkaline phosphatase, type I collagen and proliferation

1 reference

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7 January 2021

Production of osteocalcin by human bone cells in vitro. Effects of 1,25(OH)2D3, 24,25(OH)2D3, parathyroid hormone, and glucocorticoids

1 reference

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7 January 2021

Multipotential cells in the bone marrow stroma: regulation in the context of organ physiology

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7 January 2021

Mutations of the GNAS1 gene, stromal cell dysfunction, and osteomalacic changes in non-McCune-Albright fibrous dysplasia of bone

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7 January 2021

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1 reference

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7 January 2021

Development and characterization of a conditionally transformed adult human osteoblastic cell line

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7 January 2021

Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: a comparative histomorphometric study

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7 January 2021

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

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7 January 2021

Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival

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7 January 2021

Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation

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7 January 2021

Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages

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7 January 2021

Glutamate receptors are expressed by bone cells and are involved in bone resorption

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7 January 2021

Prediction of rapid bone loss in postmenopausal women

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7 January 2021

Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells.

1 reference

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7 January 2021

Immortalization and characterization of bone marrow stromal fibroblasts from a patient with a loss of function mutation in the estrogen receptor-alpha gene

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7 January 2021

Microcytophotometric analysis of human osteoclast metabolism: lack of activity in certain oxidative pathways indicates inability to sustain biosynthesis during resorption

1 reference

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7 January 2021

Cytokines induce catabolic effects in cultured adipocytes by multiple mechanisms

1 reference

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7 January 2021

Osteoblastic gene expression during adipogenesis in hematopoietic supporting murine bone marrow stromal cells

1 reference

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7 January 2021

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

1 reference

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7 January 2021

Ectopic expression of the CCAAT/enhancer-binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells

1 reference

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7 January 2021

Adipogenesis in a murine bone marrow stromal cell line capable of supporting B lineage lymphocyte growth and proliferation: biochemical and molecular characterization

1 reference

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7 January 2021

Response of bone marrow stromal cells to adipogenic antagonists

1 reference

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7 January 2021

Adipogenesis in a myeloid supporting bone marrow stromal cell line

1 reference

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7 January 2021

Clonal osteoblastic cell lines from p53 null mouse calvariae are immortalized and dependent on bone morphogenetic protein 2 for mature osteoblastic phenotype

1 reference

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7 January 2021

Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice

1 reference

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7 January 2021

An established preadipose cell line and its differentiation in culture II. Factors affecting the adipose conversion

1 reference

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7 January 2021

Sensitivity of corticosteroid-dependent insulin-resistant lipogenesis in marrow preadipocytes of obese-diabetic (db/db) mice

1 reference

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7 January 2021

Corticosteroid-dependent differentiation of human marrow preadipocytes in vitro

1 reference

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7 January 2021

Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone

1 reference

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7 January 2021

Long chain fatty acids as modulators of gene transcription in preadipose cells

1 reference

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7 January 2021

Human bone tissue formation in diffusion chamber culture in vivo by bone-derived cells and marrow stromal fibroblastic cells.

1 reference

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7 January 2021

Development and characterization of conditionally immortalized osteoblast precursor cell lines from human bone marrow stroma

1 reference

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7 January 2021

Immortalization of human marrow stromal cells by retroviral transduction with a temperature sensitive oncogene: identification of bipotential precursor cells capable of directed differentiation to either an osteoblast or adipocyte phenotype

1 reference

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7 January 2021

Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha

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7 January 2021

Type beta transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts

1 reference

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7 January 2021

Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence

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7 January 2021

Effects of lifestyle interventions on bone health

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7 January 2021

Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine

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7 January 2021

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

1 reference

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7 January 2021

Hormonal responsiveness of a preadipose cell line derived from newborn mouse calvaria

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7 January 2021

Single-colony derived strains of human marrow stromal fibroblasts form bone after transplantation in vivo

1 reference

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7 January 2021

Functional characterization of N-methyl-D-aspartic acid-gated channels in bone cells

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7 January 2021

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

1 reference

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7 January 2021

CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program

1 reference

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7 January 2021

Effects of bovine parathyroid hormone and 1,25-dihydroxyvitamin D3 on the production of prostaglandins by cells derived from human bone

1 reference

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7 January 2021

Bone marrow fat content in relation to bone remodeling and serum chemistry in intact and ovariectomized dogs

1 reference

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7 January 2021

Mechanically regulated expression of a neural glutamate transporter in bone: a role for excitatory amino acids as osteotropic agents?

1 reference

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7 January 2021

Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies.

1 reference

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7 January 2021

Long-term culture of cells from bone affected by Paget’s disease

1 reference

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7 January 2021

Quantitative histological data on disuse osteoporosis: comparison with biological data

1 reference

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7 January 2021

Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: implications for osteopenic disorders

1 reference

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7 January 2021

Thiazolidinediones inhibit osteoclast-like cell formation and bone resorption in vitro

1 reference

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7 January 2021

Isolation and characterization of human clonogenic osteoblast progenitors immunoselected from fetal bone marrow stroma using STRO-1 monoclonal antibody

1 reference

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7 January 2021

Interconversion potential of cloned human marrow adipocytes in vitro

1 reference

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7 January 2021

Expression of an N-methyl-D-aspartate-type receptor by human and rat osteoblasts and osteoclasts suggests a novel glutamate signaling pathway in bone.

1 reference

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7 January 2021

The glutamate receptor antagonist MK801 modulates bone resorption in vitro by a mechanism predominantly involving osteoclast differentiation

1 reference

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7 January 2021

Stromal cell lines which support lymphocyte growth: characterization, sensitivity to radiation and responsiveness to growth factors.

1 reference

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7 January 2021

Multilineage potential of adult human mesenchymal stem cells

1 reference

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7 January 2021

A novel human bone marrow stroma-derived cell line TF274 is highly osteogenic in vitro and in vivo

1 reference

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7 January 2021

Low Body Mass Index Is an Important Risk Factor for Low Bone Mass and Increased Bone Loss in Early Postmenopausal Women

1 reference

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7 January 2021

Isolation and characterization of osteoblast precursor cells from human bone marrow

1 reference

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7 January 2021

Human bone cellsin vitro.

1 reference

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7 January 2021

Regulation of gene expression in the adipocyte: implications for obesity and proto-oncogene function

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7 January 2021

Determinants of bone density in normal women: risk factors for future osteoporosis?

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7 January 2021

Glucocorticoid regulation of alkaline phosphatase, osteocalcin, and proto-oncogenes in normal human osteoblast-like cells

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7 January 2021

The derivation and characterization of stromal cell lines from the bone marrow of p53-/- mice: new insights into osteoblast and adipocyte differentiation

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7 January 2021

PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene

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7 January 2021

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer

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7 January 2021

Bone Density in Non-Insulin-Dependent Diabetes Mellitus: The Rotterdam Study

1 reference

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7 January 2021

Antisense oligodeoxynucleotides to GS protein alpha-subunit sequence accelerate differentiation of fibroblasts to adipocytes

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7 January 2021

Different pattern of alkaline phosphatase, osteopontin, and osteocalcin expression in developing rat bone visualized by in situ hybridization

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7 January 2021

Histologic evidence for osteopenia and increased bone turnover in ovariectomized rats

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7 January 2021

Clonal osteogenic cell lines express myogenic and adipocytic developmental potential

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7 January 2021

10.1016/S8756-3282(00)00317-3

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10913909