Newer systemic antifungal agents : pharmacokinetics, safety and efficacy (Q33981062)

30 July 2017

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title

Newer systemic antifungal agents : pharmacokinetics, safety and efficacy (English)

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30 July 2017

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4

Thomas J Walsh

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30 July 2017

Helen W Boucher

1

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30 July 2017

Andreas H Groll

series ordinal

2

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30 July 2017

Christine C Chiou

series ordinal

3

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30 July 2017

1 January 2004

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30 July 2017

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30 July 2017

64

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30 July 2017

18

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30 July 2017

1997-2020

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https://scigraph.springernature.com/pub.10.2165/00003495-200464180-00001

30 July 2017

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cites work

In vitro antifungal susceptibilities of Trichosporon species.

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12 December 2020

In vitro activity of the echinocandin antifungal agent LY303,366 in comparison with itraconazole and amphotericin B against Aspergillus spp.

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12 December 2020

Compartmental pharmacokinetics of the antifungal echinocandin caspofungin (MK-0991) in rabbits

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12 December 2020

In vitro activity of FK463, a novel lipopeptide antifungal agent, against a variety of clinically important molds

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12 December 2020

Quality control limits for broth microdilution susceptibility tests of ten antifungal agents

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12 December 2020

In vitro antifungal activities of voriconazole and reference agents as determined by NCCLS methods: review of the literature

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12 December 2020

Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia

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12 December 2020

Efficacies of fluconazole, caspofungin, and amphotericin B in Candida glabrata-infected p47phox-/- knockout mice

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12 December 2020

Pharmacokinetic and pharmacodynamic modeling of anidulafungin (LY303366): reappraisal of its efficacy in neutropenic animal models of opportunistic mycoses using optimal plasma sampling

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12 December 2020

Infections due to emerging and uncommon medically important fungal pathogens

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12 December 2020

In vitro activities of investigational triazoles against Fusarium species: effects of inoculum size and incubation time on broth microdilution susceptibility test results

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12 December 2020

Breakthrough zygomycosis after voriconazole treatment in recipients of hematopoietic stem-cell transplants

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12 December 2020

In vitro activities of a new lipopeptide antifungal agent, FK463, against a variety of clinically important fungi

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12 December 2020

In vitro amphotericin B resistance in clinical isolates of Aspergillus terreus, with a head-to-head comparison to voriconazole.

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12 December 2020

Successful treatment of coccidioidal meningitis with voriconazole

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12 December 2020

A new triazole, voriconazole (UK-109,496), blocks sterol biosynthesis in Candida albicans and Candida krusei

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12 December 2020

Opportunistic mycoses in the immunocompromised host: experience at a cancer center and review

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12 December 2020

Efficacy of SCH56592 in a rabbit model of invasive aspergillosis

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12 December 2020

In vitro and in vivo activities of posaconazole against Coccidioides immitis

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12 December 2020

Experimental pulmonary aspergillosis due to Aspergillus terreus: pathogenesis and treatment of an emerging fungal pathogen resistant to amphotericin B.

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12 December 2020

Comparison of in vitro activities of voriconazole and five established antifungal agents against different species of dermatophytes using a broth macrodilution method

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12 December 2020

Trends in antifungal susceptibility of Candida spp. isolated from pediatric and adult patients with bloodstream infections: SENTRY Antimicrobial Surveillance Program, 1997 to 2000.

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12 December 2020

Successsful voriconazole treatment of disseminated fusarium infection in an immunocompromised patient

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12 December 2020

Decisions about voriconazole versus liposomal amphotericin B.

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12 December 2020

An unusual case of pulmonary invasive aspergillosis and aspergilloma cured with voriconazole in a patient with cystic fibrosis

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12 December 2020

In vitro fungicidal activities of voriconazole, itraconazole, and amphotericin B against opportunistic moniliaceous and dematiaceous fungi

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12 December 2020

In-vitro activity of voriconazole, itraconazole and amphotericin B against filamentous fungi

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12 December 2020

A randomized, double-blind, double-dummy, multicenter trial of voriconazole and fluconazole in the treatment of esophageal candidiasis in immunocompromised patients

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12 December 2020

Antifungal activity and pharmacokinetics of posaconazole (SCH 56592) in treatment and prevention of experimental invasive pulmonary aspergillosis: correlation with galactomannan antigenemia

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12 December 2020

Treatment of murine disseminated candidiasis with L-743,872

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12 December 2020

Organism-dependent fungicidal activities of azoles

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12 December 2020

Antifungal activity of voriconazole (UK-109,496), fluconazole and amphotericin B against hematogenous Candida krusei infection in neutropenic guinea pig model

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12 December 2020

In vitro activity of a new echinocandin, LY303366, and comparison with fluconazole, flucytosine and amphotericin B against Candida species

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12 December 2020

In vitro activities of four novel triazoles against Scedosporium spp

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12 December 2020

Susceptibility of fluconazole-resistant clinical isolates of Candida spp. to echinocandin LY303366, itraconazole and amphotericin B.

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12 December 2020

Voriconazole Treatment for Less‐Common, Emerging, or Refractory Fungal Infections

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12 December 2020

In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872)

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12 December 2020

Evaluation of the Etest method for determining voriconazole susceptibilities of 312 clinical isolates of Candida species by using three different agar media

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12 December 2020

A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis

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12 December 2020

Germinated and nongerminated conidial suspensions for testing of susceptibilities of Aspergillus spp. to amphotericin B, itraconazole, posaconazole, ravuconazole, and voriconazole

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12 December 2020

New drugs and novel targets for treatment of invasive fungal infections in patients with cancer

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12 December 2020

Comparison of voriconazole (UK-109,496) and itraconazole in prevention and treatment of Aspergillus fumigatus endocarditis in guinea pigs

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12 December 2020

Efficacy of voriconazole in a guinea pig model of disseminated invasive aspergillosis

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12 December 2020

In vitro susceptibilities of zygomycetes to conventional and new antifungals

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12 December 2020

The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro

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12 December 2020

Preliminary animal pharmacokinetics of the parenteral antifungal agent MK-0991 (L-743,872).

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12 December 2020

Treatment of Scedosporium apiospermum brain abscesses with posaconazole

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12 December 2020

Combination of caspofungin with inhibitors of the calcineurin pathway attenuates growth in vitro in Aspergillus species

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12 December 2020

Antifungal efficacy, safety, and single-dose pharmacokinetics of LY303366, a novel echinocandin B, in experimental pulmonary aspergillosis in persistently neutropenic rabbits

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12 December 2020

In vitro antifungal activity of posaconazole against various pathogenic fungi

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12 December 2020

Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever

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12 December 2020

In vitro susceptibilities of Candida bloodstream isolates to the new triazole antifungal agents BMS-207147, Sch 56592, and voriconazole

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12 December 2020

In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species

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12 December 2020

In vitro susceptibility testing methods for caspofungin against Aspergillus and Fusarium isolates

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12 December 2020

Pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage: case report and literature review of central nervous system pseudallescheriasis

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12 December 2020

In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds

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12 December 2020

Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits

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12 December 2020

Efficacies of two new antifungal agents, the triazole ravuconazole and the echinocandin LY-303366, in an experimental model of invasive aspergillosis

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12 December 2020

Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandin

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12 December 2020

Activity of posaconazole against Pseudallescheria boydii: in vitro and in vivo assays

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12 December 2020

Voriconazole in the treatment of aspergillosis, scedosporiosis and other invasive fungal infections in children

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12 December 2020

Successful outcome of Scedosporium apiospermum disseminated infection treated with voriconazole in a patient receiving corticosteroid therapy

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12 December 2020

Clinical pharmacology of antifungal compounds

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12 December 2020

Aspergillosis case-fatality rate: systematic review of the literature

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12 December 2020

In vitro antifungal activity of Micafungin (FK463) against dimorphic fungi: comparison of yeast-like and mycelial forms

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12 December 2020

Compartmental pharmacokinetics and tissue distribution of the antifungal echinocandin lipopeptide micafungin (FK463) in rabbits

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12 December 2020

FK463, a novel water-soluble echinocandin lipopeptide: synthesis and antifungal activity

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12 December 2020

Antifungal activity of LY303366, a novel echinocandin B, in experimental disseminated candidiasis in rabbits

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12 December 2020

Trends in the postmortem epidemiology of invasive fungal infections at a university hospital

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12 December 2020

Meningitis caused by Pseudallescheria boydii treated with voriconazole

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12 December 2020

Comparative in-vitro activity of voriconazole (UK-109,496) and six other antifungal agents against clinical isolates of Scedosporium prolificans and Scedosporium apiospermum.

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12 December 2020

In vitro activities of new and conventional antifungal agents against clinical Scedosporium isolates

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12 December 2020

In vitro activity of posaconazole against clinical isolates of dermatophytes

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12 December 2020

In vitro activity of the new triazole BMS-207147 against Aspergillus species in comparison with itraconazole and amphotericin B

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12 December 2020

In vitro synergy of caspofungin and itraconazole against Aspergillus spp.: MIC versus minimal effective concentration end points

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12 December 2020

Efficacy of ravuconazole (BMS-207147) in a guinea pig model of disseminated aspergillosis

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12 December 2020

Pharmacokinetics and safety of voriconazole following intravenous- to oral-dose escalation regimens

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12 December 2020

Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of pulmonary aspergillosis

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12 December 2020

Dosage-dependent antifungal efficacy of V-echinocandin (LY303366) against experimental fluconazole-resistant oropharyngeal and esophageal candidiasis

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12 December 2020

Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance P

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12 December 2020

Successful treatment with caspofungin of hepatosplenic candidiasis resistant to liposomal amphotericin B.

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12 December 2020

Synergy, pharmacodynamics, and time-sequenced ultrastructural changes of the interaction between nikkomycin Z and the echinocandin FK463 against Aspergillus fumigatus

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12 December 2020

In vitro activities of posaconazole, itraconazole, voriconazole, amphotericin B, and fluconazole against 37 clinical isolates of zygomycetes

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12 December 2020

Prophylactic effect of FK463, a novel antifungal lipopeptide, against Pneumocystis carinii infection in mice

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12 December 2020

Invasive aspergillosis. Disease spectrum, treatment practices, and outcomes. I3 Aspergillus Study Group

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12 December 2020

Single- and multiple-dose pharmacokinetics of caspofungin in healthy men.

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12 December 2020

Invasive pulmonary infection due to Scedosporium apiospermum in two children with chronic granulomatous disease.

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12 December 2020

Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice

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12 December 2020

Activity of MK-0991 (L-743,872), a new echinocandin, compared with those of LY303366 and four other antifungal agents tested against blood stream isolates of Candida spp

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12 December 2020

In vitro synergy of caspofungin and amphotericin B against Aspergillus and Fusarium spp.

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12 December 2020

Efficacy of ravuconazole in treatment of mucosal candidosis in SCID mice

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12 December 2020

In vitro activity of three new triazoles and one echinocandin against Candida bloodstream isolates from cancer patients

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12 December 2020

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12 December 2020

Trends in mortality due to invasive mycotic diseases in the United States, 1980-1997.

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12 December 2020

Successful treatment of ocular invasive mould infection (fusariosis) with the new antifungal agent voriconazole

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12 December 2020

Evolving risk factors for invasive fungal infections--all neutropenic patients are not the same

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12 December 2020

Use of voriconazole in treatment of Scedosporium apiospermum infection: case report

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12 December 2020

In vitro susceptibilities of Candida dubliniensis isolates tested against the new triazole and echinocandin antifungal agents

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12 December 2020

In vitro antifungal activity of FK463, a new water-soluble echinocandin-like lipopeptide

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12 December 2020

Acremonium strictum pulmonary infection in a leukemic patient successfully treated with posaconazole after failure of amphotericin B.

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12 December 2020

In vitro interaction of caspofungin acetate with voriconazole against clinical isolates of Aspergillus spp.

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12 December 2020

Metabolites of caspofungin acetate, a potent antifungal agent, in human plasma and urine

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12 December 2020

Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults

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12 December 2020

In vitro antifungal activity of BMS-207147 and itraconazole against yeast strains that are non-susceptible to fluconazole

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12 December 2020

Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis

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12 December 2020

Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosis

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12 December 2020

In vitro activity of a new semisynthetic echinocandin, LY-303366, against systemic isolates of Candida species, Cryptococcus neoformans, Blastomyces dermatitidis, and Aspergillus species

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12 December 2020

Echinocandins and pneumocandins--a new antifungal class with a novel mode of action

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12 December 2020

Recent progress and current problems in treatment of invasive fungal infections in neutropenic patients

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12 December 2020

Caspofungin: the first representative of a new antifungal class.

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12 December 2020

In vivo activity of posaconazole against Mucor spp. in an immunosuppressed-mouse model

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12 December 2020

Comparison of a new triazole, posaconazole, with itraconazole and amphotericin B for treatment of histoplasmosis following pulmonary challenge in immunocompromised mice

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12 December 2020

Comparison of caspofungin and amphotericin B for invasive candidiasis

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12 December 2020

In vitro activities of voriconazole, itraconazole, and amphotericin B against Blastomyces dermatitidis, Coccidioides immitis, and Histoplasma capsulatum

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12 December 2020

Voriconazole versus liposomal amphotericin B in patients with neutropenia and persistent fever

1 reference

12 December 2020

Differential activity of triazoles in two-drug combinations with the echinocandin caspofungin against Aspergillus fumigatus

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12 December 2020

Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

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12 December 2020

Invasive fungal infections in children: recent advances in diagnosis and treatment.

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12 December 2020

Efficacy of micafungin alone or in combination against systemic murine aspergillosis

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12 December 2020

Efficacy of ER-30346, a novel oral triazole antifungal agent, in experimental models of aspergillosis, candidiasis, and cryptococcosis

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12 December 2020

Efficacy of FK463, a (1,3)-beta-D-glucan synthase inhibitor, in disseminated azole-resistant candida albicans infection in mice

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12 December 2020

In vitro activities of voriconazole (UK-109,496) against fluconazole-susceptible and -resistant Candida albicans isolates from oral cavities of patients with human immunodeficiency virus infection

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12 December 2020

Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: recovery after posaconazole therapy

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12 December 2020

In vitro activities of caspofungin compared with those of fluconazole and itraconazole against 3,959 clinical isolates of Candida spp., including 157 fluconazole-resistant isolates.

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12 December 2020

Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis

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12 December 2020

Voriconazole treatment of disseminated paecilomyces infection in a patient with acquired immunodeficiency syndrome

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12 December 2020

Treatment of murine Candida krusei or Candida glabrata infection with L-743,872

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12 December 2020

Ocular and systemic posaconazole(SCH-56592) treatment of invasive Fusarium solani keratitis and endophthalmitis

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12 December 2020

Skull base osteitis following fungal sinusitis

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12 December 2020

Nosocomial fungemia due to Exophiala jeanselmei var. jeanselmei and a Rhinocladiella species: newly described causes of bloodstream infection

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12 December 2020

Studies of in vitro activities of voriconazole and itraconazole against Aspergillus hyphae using viability staining

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12 December 2020

Activity of micafungin (FK463) against an itraconazole-resistant strain of Aspergillus fumigatus and a strain of Aspergillus terreus demonstrating in vivo resistance to amphotericin B.

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12 December 2020

In vitro activities of ravuconazole (BMS-207147) against 541 clinical isolates of Cryptococcus neoformans

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12 December 2020

In vitro activities of voriconazole, posaconazole, and four licensed systemic antifungal agents against Candida species infrequently isolated from blood.

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12 December 2020

Cure of orthopaedic infection with Scedosporium prolificans, using voriconazole plus terbinafine, without the need for radical surgery

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12 December 2020

Efficacy of LY303366 against amphotericin B-susceptible and -resistant Aspergillus fumigatus in a murine model of invasive aspergillosis

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12 December 2020

Echinocandins--an advance in the primary treatment of invasive candidiasis

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12 December 2020

Forum report: issues in clinical trials of empirical antifungal therapy in treating febrile neutropenic patients.

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12 December 2020

Comparison of In vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts

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12 December 2020

In vitro activity of two echinocandin derivatives, LY303366 and MK-0991 (L-743,792), against clinical isolates of Aspergillus, Fusarium, Rhizopus, and other filamentous fungi

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12 December 2020

In vitro activities of posaconazole (Sch 56592) compared with those of itraconazole and fluconazole against 3,685 clinical isolates of Candida spp. and Cryptococcus neoformans

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12 December 2020

10.2165/00003495-200464180-00001

Identifiers

DOI

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Dimensions Publication ID

30 July 2017

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