Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expression (Q33980089)

30 July 2017

Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expression (English)

1 reference

30 July 2017

1 reference

Marta Miró-Murillo

1

1 reference

30 July 2017

Ainara Elorza

2

1 reference

30 July 2017

Inés Soro-Arnáiz

3

1 reference

30 July 2017

Lucas Albacete-Albacete

4

1 reference

30 July 2017

Angel Ordoñez

5

1 reference

30 July 2017

Eduardo Balsa

6

1 reference

30 July 2017

Alicia Vara-Vega

7

1 reference

30 July 2017

Silvia Vázquez

8

1 reference

30 July 2017

Esther Fuertes

9

1 reference

30 July 2017

Carmen Fernández-Criado

10

1 reference

30 July 2017

Manuel O Landázuri

11

1 reference

30 July 2017

Julián Aragonés

12

1 reference

30 July 2017

language of work or name

English

0 references

publication date

21 July 2011

1 reference

30 July 2017

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30 July 2017

6

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30 July 2017

7

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30 July 2017

e22589

1 reference

Creative Commons Attribution 4.0 International

30 July 2017

start time

21 July 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Molecular basis of cardioprotection by erythropoietin

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5 July 2018

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Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau protein

5 July 2018

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Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins

5 July 2018

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5 July 2018

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Hypoxia-inducible factor 1 (HIF-1) pathway

5 July 2018

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Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island

5 July 2018

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Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

5 July 2018

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Increased erythropoietin production after myocardial infarction in mice

5 July 2018

1 reference

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Regulation of erythropoietin production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141062

Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.

5 July 2018

1 reference

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Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

5 July 2018

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Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells

5 July 2018

1 reference

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Cardiac physiology at the cellular level: use of cultured HL-1 cardiomyocytes for studies of cardiac muscle cell structure and function

5 July 2018

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HIF-1 as a target for drug development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141062

Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway

5 July 2018

1 reference

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A conserved family of prolyl-4-hydroxylases that modify HIF

5 July 2018

1 reference

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

5 July 2018

1 reference

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

5 July 2018

1 reference

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

5 July 2018

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Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

5 July 2018

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Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia

5 July 2018

1 reference

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

5 July 2018

1 reference

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Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains

5 July 2018

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Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

5 July 2018

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In vivo and in vitro regulation of erythropoietin mRNA: measurement by competitive polymerase chain reaction

5 July 2018

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Studies on the liver to kidney switch of erythropoietin production

5 July 2018

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Regulation of the erythropoietin gene in Hep 3B cells

5 July 2018

1 reference

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ER-based double iCre fusion protein allows partial recombination in forebrain

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022589

Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022589

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022589

Excessive erythrocytosis in adult mice overexpressing erythropoietin leads to hepatic, renal, neuronal, and muscular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022589

Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022589

Hypoxia-inducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022589

Constitutively overexpressed erythropoietin reduces infarct size in a mouse model of permanent coronary artery ligation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141062

Persistent induction of HIF-1alpha and -2alpha in cardiomyocytes and stromal cells of ischemic myocardium

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141062

Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141062

Transgenic mice overexpressing erythropoietin adapt to excessive erythrocytosis by regulating blood viscosity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141062

Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141062

Involvement of hypoxia-inducible factor 1 in human cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141062

HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141062

Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21811636

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of the erythropoietin gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21811636

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21811636

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0022589

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference