Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites (Q33979170)

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English	Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

30 July 2017

Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites (English)

1 reference

Europe PubMed Central

30 July 2017

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Plasmodium falciparum

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author name string

A M Nzila

1

1 reference

Europe PubMed Central

30 July 2017

E K Mberu

2

1 reference

Europe PubMed Central

30 July 2017

J Sulo

3

1 reference

Europe PubMed Central

30 July 2017

H Dayo

4

1 reference

Europe PubMed Central

30 July 2017

P A Winstanley

5

1 reference

Europe PubMed Central

30 July 2017

C H Sibley

6

1 reference

Europe PubMed Central

30 July 2017

W M Watkins

7

1 reference

Europe PubMed Central

30 July 2017

language of work or name

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publication date

1 April 2000

1 reference

Europe PubMed Central

30 July 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

30 July 2017

44

1 reference

Europe PubMed Central

30 July 2017

991-996

1 reference

Europe PubMed Central

30 July 2017

4

1 reference

Europe PubMed Central

30 July 2017

Strategies for the prevention of antimalarial drug resistance: rationale for combination chemotherapy for malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89803

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The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses

1 reference

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Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy

1 reference

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5 July 2018

Selection and synergy in Plasmodium falciparum

1 reference

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5 July 2018

Polymorphisms in the dihydrofolate reductase (DHFR) and dihydropteroate synthetase (DHPS) genes of Plasmodium falciparum and in vivo resistance to sulphadoxine/pyrimethamine in isolates from Tanzania

1 reference

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5 July 2018

Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria

1 reference

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5 July 2018

Molecular basis of in vivo resistance to sulfadoxine-pyrimethamine in African adult patients infected with Plasmodium falciparum malaria parasites.

1 reference

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Plasmodium falciparum: detection of polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes by PCR and restriction digestion

1 reference

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5 July 2018

In vivo selection for a specific genotype of dihydropteroate synthetase of Plasmodium falciparum by pyrimethamine-sulfadoxine but not chlorproguanil-dapsone treatment

1 reference

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Molecular epidemiology of malaria in Yaounde, Cameroon II. Baseline frequency of point mutations in the dihydropteroate synthase gene of Plasmodium falciparum.

1 reference

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Kenyan Plasmodium falciparum field isolates: correlation between pyrimethamine and chlorcycloguanil activity in vitro and point mutations in the dihydrofolate reductase domain.

1 reference

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Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance

1 reference

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5 July 2018

Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum

1 reference

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5 July 2018

Antifolate drug resistance and point mutations in Plasmodium falciparum in Kenya

1 reference

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5 July 2018

Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins

1 reference

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Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria.

1 reference

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5 July 2018

Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89803

5 July 2018

Plasmodium falciparum: mutation pattern in the dihydrofolate reductase-thymidylate synthase genes of Vietnamese isolates, a novel mutation, and coexistence of two clones in a Thai patient.

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Iron, but not folic acid, combined with effective antimalarial therapy promotes haematological recovery in African children after acute falciparum malaria

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5 July 2018

Beyond chloroquine: implications of drug resistance for evaluating malaria therapy efficacy and treatment policy in Africa

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5 July 2018

Epidemiology of drug resistance in malaria

1 reference

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5 July 2018

Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum

1 reference

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5 July 2018

Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine.

1 reference

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5 July 2018

Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum

1 reference

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Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89803

5 July 2018

Characterisation of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine

1 reference

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Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria

1 reference

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Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance

1 reference

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Antimalarial drug resistance: the pace quickens

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Pyrimethamine-sulfadoxine efficacy and selection for mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase in Mali

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Molecular assays for surveillance of antifolate-resistant malaria

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A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance.

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Point mutations in the dihydrofolate reductase and dihydropteroate synthetase genes and in vitro susceptibility to pyrimethamine and cycloguanil of Plasmodium falciparum isolates from Papua New Guinea

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Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum.

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Chemotherapy of malaria and resistance to antimalarials. Report of a WHO scientific group

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https://pubmed.ncbi.nlm.nih.gov/10722502

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On ;the efficacy of antifolate antimalarial combinations in Africa'

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Identifiers

10.1128/AAC.44.4.991-996.2000

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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