Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism. (Q33977228)

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English	Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism.	scientific article

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21 February 2020

Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism (English)

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21 February 2020

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21 February 2020

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Shripad D Chitnis

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21 February 2020

Björn Schniedewind

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21 February 2020

Reginald Y Gohh

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21 February 2020

Uwe Christians

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21 February 2020

Fatemeh Akhlaghi

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21 February 2020

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2 January 2013

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21 February 2020

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21 February 2020

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21 February 2020

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21 February 2020

641-649

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21 February 2020

Effect of diabetes mellitus on pharmacokinetic and pharmacodynamic properties of drugs

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5 July 2018

Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus

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5 July 2018

Diabetes mellitus reduces activity of human UDP-glucuronosyltransferase 2B7 in liver and kidney leading to decreased formation of mycophenolic acid acyl-glucuronide metabolite

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5 July 2018

Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I.

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5 July 2018

Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics

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5 July 2018

Functional interactions between P-glycoprotein and CYP3A in drug metabolism

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5 July 2018

Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro

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5 July 2018

Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation

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5 July 2018

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

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5 July 2018

Genetic contribution to variable human CYP3A-mediated metabolism

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5 July 2018

Hepatic cytochrome P450 regulation in disease states

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5 July 2018

The pharmacokinetics and metabolic disposition of tacrolimus: a comparison across ethnic groups

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5 July 2018

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

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5 July 2018

Tacrolimus dosing requirements in diabetic and nondiabetic patients calculated from pretransplantation data

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5 July 2018

Clinical pharmacokinetics of tacrolimus

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5 July 2018

Disease-induced variations in plasma protein levels. Implications for drug dosage regimens (Part I).

1 reference

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5 July 2018

Pharmacokinetics of mycophenolic acid and metabolites in diabetic kidney transplant recipients

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.752118

21 January 2018

Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.752118

21 January 2018

Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.752118

21 January 2018

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.752118

21 January 2018

Associations of pretransplant diabetes mellitus, new-onset diabetes after transplant, and acute rejection with transplant outcomes: an analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) database.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.752118

21 January 2018

Dynamic and kinetic disposition of nisoldipine enantiomers in hypertensive patients presenting with type-2 diabetes mellitus.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.752118

21 January 2018

Tacrolimus in diabetic kidney transplant recipients: pharmacokinetics and application of a limited sampling strategy.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.752118

21 January 2018

Pharmacokinetics of lidocaine and its metabolite in peridural anesthesia administered to pregnant women with gestational diabetes mellitus

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21 January 2018

Quantification of cyclosporine and tacrolimus in whole blood. Comparison of liquid chromatography-electrospray mass spectrometry with the enzyme multiplied immunoassay technique

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29 October 2018

The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels

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29 October 2018

Automated, fast and sensitive quantification of drugs in blood by liquid chromatography-mass spectrometry with on-line extraction: immunosuppressants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116556

29 October 2018

Human P-glycoprotein transports cyclosporin A and FK506.

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29 October 2018

Diabetes mellitus reduces the clearance of atorvastatin lactone: results of a population pharmacokinetic analysis in renal transplant recipients and in vitro studies using human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The concentration of cyclosporine metabolites is significantly lower in kidney transplant recipients with diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In Vitro Investigation of Human UDP-Glucuronosyltransferase Isoforms Responsible for Tacrolimus Glucuronidation: Predominant Contribution of UGT1A4

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of gestational diabetes mellitus on the stereoselective kinetic disposition and metabolism of labetalol in hypertensive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetic determinants of the CYP3A5 polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FK 506 metabolism in human liver microsomes: investigation of the involvement of cytochrome P450 isozymes other than CYP3A4

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excretion of tacrolimus glucuronides in human bile

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3109/00498254.2012.752118

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23278282%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23278282%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23278282%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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