Disruption of lysosome function promotes tumor growth and metastasis in Drosophila (Q33967318)

30 July 2017

title

Disruption of lysosome function promotes tumor growth and metastasis in Drosophila (English)

1 reference

30 July 2017

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Deep orange Dmel_CG3093

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GOA release 2020-03-11

Carnation Dmel_CG12230

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GOA release 2020-03-11

author name string

Congwu Chi

1

1 reference

30 July 2017

Huanhu Zhu

2

1 reference

30 July 2017

Min Han

3

1 reference

30 July 2017

Yuan Zhuang

4

1 reference

30 July 2017

Xiaohui Wu

5

1 reference

30 July 2017

Tian Xu

6

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30 July 2017

language of work or name

English

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publication date

25 April 2010

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Journal of Biological Chemistry

30 July 2017

published in

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30 July 2017

volume

285

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30 July 2017

issue

28

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30 July 2017

page(s)

21817-21823

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Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

All-you-can-eat: autophagy in neurodegeneration and neuroprotection.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Role of autophagy in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Ubiquitylation and degradation of serum-inducible kinase by hVPS18, a RING-H2 type ubiquitin ligase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

The role of autophagy in cancer development and response to therapy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Role and regulation of starvation-induced autophagy in the Drosophila fat body

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

5 July 2018

Endocytosis and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

A Genetic Screen in Drosophila for Metastatic Behavior

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

The Role of mVps18p in Clustering, Fusion, and Intracellular Localization of Late Endocytic Organelles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

deep-orange and carnation define distinct stages in late endosomal biogenesis in Drosophila melanogaster

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Molecular characterization of mammalian homologues of class C Vps proteins that interact with syntaxin-7

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Molecular cloning and characterization of human VPS18, VPS 11, VPS16, and VPS33.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Induction of autophagy and inhibition of tumorigenesis by beclin 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Enhanced growth of mammary adenocarcinoma in rats by chloroquine and quinacrine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Transposition of cloned P elements into Drosophila germ line chromosomes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Regulation of protein turnover versus growth state. Studies on the mechanism(s) of initiation of acidic vacuolar proteolysis in cells of stationary ascites hepatoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Cathepsin D: a protease involved in breast cancer metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Inhibition of the Lysosomal Pathway of Protein Degradation in Isolated Rat Hepatocytes by Ammonia, Methylamine, Chloroquine and Leupeptin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

Regulation of protein degradation in normal and transformed human cells. Effects of growth state, medium composition, and viral transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898421

A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.131714

Drosophila Vps16A is required for trafficking to lysosomes and biogenesis of pigment granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.131714

Not just pretty eyes: Drosophila eye-colour mutations and lysosomal delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.131714

A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.131714

The zebrafish mutant vps18 as a model for vesicle-traffic related hypopigmentation diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.131714

Making a better RNAi vector for Drosophila: use of intron spacers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.131714

Molecular characterization of the deep orange (dor) gene of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.131714

Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.131714

Increased cathepsin D level in the serum of patients with metastatic breast carcinoma detected with a specific pro-cathepsin D immunoassay

21 January 2018

1 reference

12 December 2020

Effect of carboxylic ionophores on lysosomal protein degradation in rat hepatocytes

1 reference

12 December 2020

Serum cathepsin B levels and urinary excretion of cathepsin B in the cancer patients with remote metastasis

1 reference

12 December 2020

Reduced expression of vps11 causes less pigmentation in medaka, Oryzias latipes

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.131714

1 reference

30 July 2017

1 reference

30 July 2017

1 reference