An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 rev prevents viral production. (Q33967157)

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English	An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 rev prevents viral production.	scientific article

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31 January 2020

An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 rev prevents viral production (English)

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author name string

Thomas Vercruysse

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publication date

20 April 2010

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13

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Journal of Biological Chemistry

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21768-21780

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31 January 2020

HIV-1 Rev protein assembles on viral RNA one molecule at a time

1 reference

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Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus

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5 July 2018

A solution to limited genomic capacity: using adaptable binding surfaces to assemble the functional HIV Rev oligomer on RNA

1 reference

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5 July 2018

Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA.

1 reference

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5 July 2018

Arginine-rich motifs present multiple interfaces for specific binding by RNA.

1 reference

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5 July 2018

Small-molecule inhibition of TNF-alpha

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5 July 2018

Kinetic and molecular analysis of nuclear export factor CRM1 association with its cargo in vivo

1 reference

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5 July 2018

A DEAD box protein facilitates HIV-1 replication as a cellular co-factor of Rev.

1 reference

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5 July 2018

Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function

1 reference

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5 July 2018

Small-molecule inhibitors of the p53 suppressor HDM2: have protein-protein interactions come of age as drug targets?

1 reference

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5 July 2018

Automatic and quantitative measurement of protein-protein colocalization in live cells.

1 reference

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5 July 2018

A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export

1 reference

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5 July 2018

Solid-state NMR data support a helix-loop-helix structural model for the N-terminal half of HIV-1 Rev in fibrillar form

1 reference

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5 July 2018

Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae

1 reference

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5 July 2018

Structural model for the cooperative assembly of HIV-1 Rev multimers on the RRE as deduced from analysis of assembly-defective mutants

1 reference

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5 July 2018

Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains

1 reference

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5 July 2018

THE HIV-1 REV PROTEIN

1 reference

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5 July 2018

Three-dimensional structure of HIV-1 Rev protein filaments

1 reference

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5 July 2018

Functional analysis of the human immunodeficiency virus type 1 Rev protein oligomerization interface.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

5 July 2018

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

5 July 2018

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

5 July 2018

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

5 July 2018

Selection and identification of single domain antibody fragments from camel heavy-chain antibodies

1 reference

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5 July 2018

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

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5 July 2018

Naturally occurring antibodies devoid of light chains

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5 July 2018

Potent inhibition of human immunodeficiency virus type 1 replication by an intracellular anti-Rev single-chain antibody

1 reference

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5 July 2018

A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

5 July 2018

Construction and in vitro properties of HIV-1 mutants with deletions in "nonessential" genes

1 reference

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5 July 2018

A molecular rheostat. Co-operative rev binding to stem I of the rev-response element modulates human immunodeficiency virus type-1 late gene expression

1 reference

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5 July 2018

Continuous propagation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes

1 reference

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5 July 2018

The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

5 July 2018

The human immunodeficiency virus type 1 Rev protein shuttles between the cytoplasm and nuclear compartments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

5 July 2018

RNA recognition by an isolated alpha helix

1 reference

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5 July 2018

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1 reference

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5 July 2018

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

5 July 2018

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1 reference

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5 July 2018

The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region

1 reference

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5 July 2018

Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression

1 reference

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5 July 2018

Functional analysis of CAR, the target sequence for the Rev protein of HIV-1.

1 reference

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5 July 2018

Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro

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5 July 2018

Nucleotide sequence of Mason-Pfizer monkey virus: an immunosuppressive D-type retrovirus

1 reference

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5 July 2018

Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function

1 reference

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5 July 2018

Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminus

1 reference

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5 July 2018

HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency

1 reference

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5 July 2018

Efficient replication of human immunodeficiency virus type 1 requires a threshold level of Rev: potential implications for latency

1 reference

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5 July 2018

Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein

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5 July 2018

Inhibition of human immunodeficiency virus type 1 replication in human T cells by retroviral-mediated gene transfer of a dominant-negative Rev trans-activator

1 reference

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5 July 2018

Inhibition of the CRM1-mediated nucleocytoplasmic transport by N-azolylacrylates: structure-activity relationship and mechanism of action

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29 October 2018

Quantitative FRAP in analysis of molecular binding dynamics in vivo.

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29 October 2018

In vivo HIV-1 Rev multimerization in the nucleolus and cytoplasm identified by fluorescence resonance energy transfer.

1 reference

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29 October 2018

An RNA-binding chameleon

1 reference

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29 October 2018

A cis-acting peptide signal in human immunodeficiency virus type I Rev which inhibits nuclear entry of small proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

29 October 2018

Sequence requirements for Rev multimerization in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

29 October 2018

A molecular clone of HTLV-III with biological activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898381

29 October 2018

Helix-loop-helix motif in HIV-1 Rev

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.112490

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406803%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406803%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406803%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

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