Comparative pathogenesis and systems biology for biodefense virus vaccine development (Q33959989)

30 July 2017

3 references

20 June 2019

1 September 2020

2 October 2020

Comparative pathogenesis and systems biology for biodefense virus vaccine development (English)

1 reference

30 July 2017

1 reference

1 September 2020

1 reference

2 October 2020

2

Alan D T Barrett

1 reference

30 July 2017

Gavin C Bowick

1

1 reference

30 July 2017

6 June 2010

4 references

Journal of Biomedicine and Biotechnology

30 July 2017

20 June 2019

1 September 2020

2 October 2020

4 references

30 July 2017

20 June 2019

1 September 2020

2 October 2020

2010

1 reference

30 July 2017

236528

1 reference

Creative Commons Attribution 3.0 Unported

30 July 2017

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening

28 July 2018

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Attenuated and lethal variants of Pichindé virus induce differential patterns of NF-kappaB activation suggesting a potential target for novel therapeutics

28 July 2018

1 reference

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Evolutionarily conserved herpesviral protein interaction networks

28 July 2018

1 reference

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Yellow fever vaccine - how does it work and why do rare cases of serious adverse events take place?

28 July 2018

1 reference

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Nipah virus sequesters inactive STAT1 in the nucleus via a P gene-encoded mechanism

28 July 2018

1 reference

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Application of pharmacogenomics to vaccines

28 July 2018

1 reference

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Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection

28 July 2018

1 reference

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Gene expression in primate liver during viral hemorrhagic fever

28 July 2018

1 reference

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The role of RNA folding free energy in the evolution of the polymerase genes of the influenza A virus

28 July 2018

1 reference

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The use of genomics in microbial vaccine development

28 July 2018

1 reference

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28 July 2018

1 reference

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Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

28 July 2018

1 reference

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Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Analysis of the differential host cell nuclear proteome induced by attenuated and virulent hemorrhagic arenavirus infection

28 July 2018

1 reference

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Case of yellow fever vaccine--associated viscerotropic disease with prolonged viremia, robust adaptive immune responses, and polymorphisms in CCR5 and RANTES genes

28 July 2018

1 reference

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Virus attenuation by genome-scale changes in codon pair bias

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Genome comparison of virulent and avirulent strains of the Pichinde arenavirus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Genistein treatment of cells inhibits arenavirus infection

28 July 2018

1 reference

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Early blood profiles of virus infection in a monkey model for Lassa fever.

28 July 2018

1 reference

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Epstein-Barr virus and virus human protein interaction maps

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Predicting protein-protein interactions based only on sequences information

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

A ML29 reassortant virus protects guinea pigs against a distantly related Nigerian strain of Lassa virus and can provide sterilizing immunity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Protein sequence database for pathogenic arenaviruses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Identification of differentially activated cell-signaling networks associated with pichinde virus pathogenesis by using systems kinomics.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Differential signaling networks induced by mild and lethal hemorrhagic fever virus infections

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Herpesviral protein networks and their interaction with the human proteome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

A live attenuated vaccine for Lassa fever made by reassortment of Lassa and Mopeia viruses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Attenuated rabies virus activates, while pathogenic rabies virus evades, the host innate immune responses in the central nervous system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

A network-based analysis of systemic inflammation in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Development of a new vaccine for the prevention of Lassa fever

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Human macrophages, but not dendritic cells, are activated and produce alpha/beta interferons in response to Mopeia virus infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

CARRIE web service: automated transcriptional regulatory network inference and interactive analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Lassa virus infection of human dendritic cells and macrophages is productive but fails to activate cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

African swine fever virus multigene family 360 and 530 genes affect host interferon response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Cytoscape: a software environment for integrated models of biomolecular interaction networks

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Low levels of interleukin-8 and interferon-inducible protein-10 in serum are associated with fatal infections in acute Lassa fever

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

African Swine Fever Virus Multigene Family 360 and 530 Genes Are Novel Macrophage Host Range Determinants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Genetic evidence for an interferon-antagonistic function of rift valley fever virus nonstructural protein NSs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

The S segment of rift valley fever phlebovirus (Bunyaviridae) carries determinants for attenuation and virulence in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Lassa and Mopeia virus replication in human monocytes/macrophages and in endothelial cells: different effects on IL-8 and TNF-alpha gene expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Protective efficacy of a live attenuated vaccine against Argentine hemorrhagic fever. AHF Study Group

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

An IkappaB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Pathological and virological features of arenavirus disease in guinea pigs. Comparison of two Pichinde virus strains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Characterization of clone 13, a naturally attenuated avirulent isolate of Rift Valley fever virus, which is altered in the small segment.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Pathogenesis of a Pichinde Virus Strain Adapted to Produce Lethal Infections in Guinea Pigs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Reversion to neurovirulence of the live-attenuated Sabin type 3 oral pollovirus vaccine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Protection of rhesus monkeys from fatal Lassa fever by vaccination with a recombinant vaccinia virus containing the Lassa virus glycoprotein gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Effective vaccine for lassa fever

28 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Experimental vaccine may have saved Hamburg scientist from Ebola fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Reverse Vaccinology and Genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Cellular immune response to Marburg virus infection in cynomolgus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

A nonessential African swine fever virus gene UK is a significant virulence determinant in domestic swine

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Computational inference of transcriptional regulatory networks from expression profiling and transcription factor binding site identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Differential inhibition of type I interferon induction by arenavirus nucleoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Development of infectious clones for virulent and avirulent pichinde viruses: a model virus to study arenavirus-induced hemorrhagic fevers

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Molecular networks as sensors and drivers of common human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Prediction of protein-protein interaction sites using support vector machines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Immune response during adverse events after 17D-derived yellow fever vaccination in Europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Molecular and cellular signatures of human vaccine adjuvants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

The acquired immune response to the mucosal adjuvant LTK63 imprints the mouse lung with a protective signature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Emerging zoonoses: the challenge for public health and biodefense

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Personalized vaccines: the emerging field of vaccinomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F236528

Improving the performance of an SVM-based method for predicting protein-protein interactions.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896660

Safety of 17D derived yellow fever vaccines

29 October 2018

1 reference

12 December 2020

Intramuscular inoculation of Sin Nombre hantavirus cDNAs induces cellular and humoral immune responses in BALB/c mice

1 reference

12 December 2020

Genetic vaccines protect against Sin Nombre hantavirus challenge in the deer mouse (Peromyscus maniculatus)

1 reference

12 December 2020

Cytoscape: a community-based framework for network modeling

1 reference

12 December 2020

A conserved African swine fever virus IkappaB homolog, 5EL, is nonessential for growth in vitro and virulence in domestic swine

1 reference

12 December 2020

Identifiers

DOI

10.1155/2010/236528

1 reference

30 July 2017

1 reference

30 July 2017

1 reference

PubMed ID

20617142