Allosteric regulation of the discriminative responsiveness of retinoic acid receptor to natural and synthetic ligands by retinoid X receptor and DNA. (Q33957795)

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English	Allosteric regulation of the discriminative responsiveness of retinoic acid receptor to natural and synthetic ligands by retinoid X receptor and DNA.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Allosteric regulation of the discriminative responsiveness of retinoic acid receptor to natural and synthetic ligands by retinoid X receptor and DNA. (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

based on heuristic

inferred from title

author name string

Mouchon A

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Delmotte MH

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Formstecher P

3

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Europe PubMed Central

PubMed publication ID

30 July 2017

Lefebvre P

4

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Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

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publication date

1 April 1999

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Europe PubMed Central

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30 July 2017

Molecular and Cellular Biology

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Europe PubMed Central

PubMed publication ID

30 July 2017

19

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Europe PubMed Central

PubMed publication ID

30 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

3073-3085

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

1 reference

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Structure and specificity of nuclear receptor-coactivator interactions

1 reference

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Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2.

1 reference

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Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators

1 reference

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

1 reference

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5 July 2018

H11-H12 loop retinoic acid receptor mutants exhibit distinct trans-activating and trans-repressing activities in the presence of natural or synthetic retinoids

1 reference

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Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors

1 reference

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The histone acetylase PCAF is a nuclear receptor coactivator.

1 reference

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Atomic structure of progesterone complexed with its receptor

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Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation

1 reference

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5 July 2018

Binding of retinoic acid receptor heterodimers to DNA. A role for histones NH2 termini.

1 reference

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Conformational adaptation of agonists to the human nuclear receptor RAR gamma

1 reference

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The receptor-associated coactivator 3 activates transcription through CREB-binding protein recruitment and autoregulation

1 reference

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5 July 2018

Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells

1 reference

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5 July 2018

Molecular basis of agonism and antagonism in the oestrogen receptor

1 reference

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5 July 2018

Activation of the orphan receptor RIP14 by retinoids

1 reference

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Pharmacology and chemistry of adapalene

1 reference

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5 July 2018

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

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5 July 2018

The promoter context is a decisive factor in establishing selective responsiveness to nuclear class II receptors

1 reference

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AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors

1 reference

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5 July 2018

The phantom ligand effect: allosteric control of transcription by the retinoid X receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

5 July 2018

Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression

1 reference

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5 July 2018

Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

5 July 2018

The CBP co-activator is a histone acetyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

5 July 2018

Analysis of the ligand-binding domain of human retinoic acid receptor alpha by site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

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Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

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The receptor-DNA complex determines the retinoid response: a mechanism for the diversification of the ligand signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

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Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

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RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo

1 reference

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The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

1 reference

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Mutations that alter ligand-induced switches and dimerization activities in the retinoid X receptor

1 reference

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5 July 2018

Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor alpha

1 reference

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Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity

1 reference

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Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding

1 reference

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Vitamin A, differentiation and cancer

1 reference

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Endogenous retinoic acid receptor (RAR)-retinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid-responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers

1 reference

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Separation of transactivation and AP1 antagonism functions of retinoic acid receptor alpha

1 reference

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Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

1 reference

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Protein phosphatases 1 and 2A regulate the transcriptional and DNA binding activities of retinoic acid receptors

1 reference

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Mutagenesis of the ligand binding domain of the human retinoic acid receptor alpha identifies critical residues for 9-cis-retinoic acid binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

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Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor

1 reference

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5 July 2018

The roles of retinoids in vertebrate development

1 reference

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A transcriptional co-repressor that interacts with nuclear hormone receptors

1 reference

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5 July 2018

Polarity-specific activities of retinoic acid receptors determined by a co-repressor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

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A structural role for hormone in the thyroid hormone receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

5 July 2018

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

5 July 2018

Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

1 reference

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5 July 2018

Retinoic acid and synthetic analogs differentially activate retinoic acid receptor dependent transcription

1 reference

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Selective high affinity retinoic acid receptor alpha or beta-gamma ligands

1 reference

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All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs.

1 reference

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5 July 2018

Selective Synthetic Ligands for Human Nuclear Retinoic Acid Receptors

1 reference

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5 July 2018

Distinct modes of interaction of the retinoic acid receptor alpha with natural and synthetic retinoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

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The nuclear receptor ligand-binding domain: structure and function

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

29 October 2018

Co-activators and co-repressors in the integration of transcriptional responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

29 October 2018

Allosteric effects of DNA on transcriptional regulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84101

29 October 2018

Structural determinants of the ligand-binding site of the human retinoic acid receptor alpha.

1 reference

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29 October 2018

Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10082574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential role of homologous positively charged amino acid residues for ligand binding in retinoic acid receptor alpha compared with retinoic acid receptor beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/10082574

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based on heuristic

inferred from PubMed ID database lookup

Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10082574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A canonical structure for the ligand-binding domain of nuclear receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10082574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of amino acids critical for the DNA binding and dimerization properties of the human retinoic acid receptor alpha. Importance of lysine 360, lysine 365, and valine 361

1 reference

https://pubmed.ncbi.nlm.nih.gov/10082574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two distinct actions of retinoid-receptor ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/10082574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.19.4.3073

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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