Islet amyloid and type 2 diabetes: overproduction or inadequate clearance and detoxification? (Q33944160)

30 July 2017

Islet amyloid and type 2 diabetes: overproduction or inadequate clearance and detoxification? (English)

1 reference

30 July 2017

1 reference

Dhananjay Gupta

1

1 reference

PubMed ID

25036704

30 July 2017

Jack L Leahy

series ordinal

2

1 reference

PubMed ID

25036704

30 July 2017

language of work or name

English

0 references

publication date

18 July 2014

1 reference

Journal of Clinical Investigation

30 July 2017

1 reference

30 July 2017

124

1 reference

30 July 2017

8

1 reference

30 July 2017

3292-3294

1 reference

Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Autophagy modulation as a potential therapeutic target for diverse diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Autophagy: renovation of cells and tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Fatty acids suppress autophagic turnover in β-cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Autophagy regulates lipid metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Pancreatic islet cell autophagy during aging in rats.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Autophagy in human type 2 diabetes pancreatic beta cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109527

Sequence divergence in a specific region of islet amyloid polypeptide (IAPP) explains differences in islet amyloid formation between species

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25036704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI77506

1 reference

30 July 2017

1 reference

30 July 2017

1 reference

PubMed ID

25036704