Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice (Q33941361)

30 July 2017

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title

Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice (English)

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30 July 2017

Levy DE

1

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30 July 2017

Gilliland DG

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 May 2000

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30 July 2017

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30 July 2017

19

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30 July 2017

21

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30 July 2017

2505-2510

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203480

30 July 2017

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cites work

Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

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7 January 2021

Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection

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7 January 2021

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

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7 January 2021

STAT proteins as novel targets for cancer therapy. Signal transducer an activator of transcription

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7 January 2021

Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice

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7 January 2021

Distribution of the mammalian Stat gene family in mouse chromosomes

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Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation

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7 January 2021

Jak-STAT signaling induced by the v-abl oncogene

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7 January 2021

STATs and gene regulation

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7 January 2021

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

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7 January 2021

Interferon-gamma-induced transcriptional activation is mediated by protein kinase C

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7 January 2021

Molecular cloning of a gene selectively induced by gamma interferon from human macrophage cell line U937.

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Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

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Immune response in mice that lack the interferon-gamma receptor

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A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses

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7 January 2021

P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

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7 January 2021

Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity

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7 January 2021

Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

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7 January 2021

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

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7 January 2021

Transcriptional induction of two genes in human cells by beta interferon

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7 January 2021

Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes

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7 January 2021

STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma

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7 January 2021

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities

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7 January 2021

Stat5a is mandatory for adult mammary gland development and lactogenesis.

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7 January 2021

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

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7 January 2021

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

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7 January 2021

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways

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7 January 2021

Functional role of type I and type II interferons in antiviral defense

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7 January 2021

An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction

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7 January 2021

Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

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7 January 2021

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse

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7 January 2021

Transforming properties of the Huntingtin interacting protein 1/ platelet-derived growth factor beta receptor fusion protein.

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7 January 2021

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

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7 January 2021

FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway

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7 January 2021

Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha

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7 January 2021

Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Strain-dependent epithelial defects in mice lacking the EGF receptor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203480

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203480

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Dimensions Publication ID

30 July 2017

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