Reprogramming transcription during the differentiation of precursor CD4+ T cells into effector Th1 and Th2 cells (Q33939862)

30 July 2017

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title

Reprogramming transcription during the differentiation of precursor CD4+ T cells into effector Th1 and Th2 cells (English)

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30 July 2017

M Rincón

1

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PubMed ID

10847765

30 July 2017

R A Flavell

series ordinal

2

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30 July 2017

1 January 1999

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30 July 2017

8

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inferred from page(s)

published in

Microbes and Infection

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30 July 2017

1

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30 July 2017

1

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30 July 2017

43-50

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Differential transcription directed by discrete gamma interferon promoter elements in naive and memory (effector) CD4 T cells and CD8 T cells

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

B70 antigen is a second ligand for CTLA-4 and CD28.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Effect of inhibitors of eicosanoid metabolism in murine collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Identifying differences in mRNA expression by representational difference analysis of cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Nuclear factor of activated T cells contains Fos and Jun.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

The role of the CD28 receptor during T cell responses to antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

NF-AT components define a family of transcription factors targeted in T-cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Lymphocyte responses and cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

The Proximal Regulatory Element of the Interferon-γ Promoter Mediates Selective Expression in T Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Transcription factors of the NFAT family: regulation and function

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Pyridinyl imidazoles inhibit the inflammatory phase of delayed type hypersensitivity reactions without affecting T-dependent immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Reprogramming the signalling requirement for AP-1 (activator protein-1) activation during differentiation of precursor CD4+ T-cells into effector Th1 and Th2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

T-cell subsets: transcriptional control in the Th1/Th2 decision

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Lifespans of naive, memory and effector lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

T-Cell Subsets: Who does the polarizing?

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Essential role of Stat6 in IL-4 signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Lifespan of lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

An enhanced immune response in mice lacking the transcription factor NFAT1.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2899%2980013-6

7 January 2021

10.1016/S1286-4579(99)80013-6

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10847765