Manipulation of death pathways in desmin-related cardiomyopathy (Q33931515)

30 July 2017

Manipulation of death pathways in desmin-related cardiomyopathy (English)

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30 July 2017

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Alina Maloyan

1

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30 July 2017

Jennifer Sayegh

2

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30 July 2017

Hanna Osinska

3

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30 July 2017

Balvin H L Chua

4

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30 July 2017

Jeffrey Robbins

5

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30 July 2017

1 April 2010

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30 July 2017

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30 July 2017

106

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9

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1524-1532

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describes a project that uses

30 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2890082/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy

1 reference

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Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

5 July 2018

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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

5 July 2018

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Autophagy is an adaptive response in desmin-related cardiomyopathy

5 July 2018

1 reference

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The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

5 July 2018

1 reference

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Molecular mechanisms and pathophysiology of necrotic cell death

5 July 2018

1 reference

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Clearance of mutant aggregate-prone proteins by autophagy.

5 July 2018

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Expansion and evolution of cell death programmes

5 July 2018

1 reference

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Autophagy in the Pathogenesis of Disease

5 July 2018

1 reference

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The BCL-2 protein family: opposing activities that mediate cell death

5 July 2018

1 reference

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A multiplicity of cell death pathways. Symposium on apoptotic and non-apoptotic cell death pathways

5 July 2018

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TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways

5 July 2018

1 reference

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Cardiac autophagy is a maladaptive response to hemodynamic stress

5 July 2018

1 reference

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Cell death modalities: classification and pathophysiological implications

5 July 2018

1 reference

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Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy

5 July 2018

1 reference

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Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

5 July 2018

1 reference

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Mitochondrial membrane permeabilization in cell death

5 July 2018

1 reference

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Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Death begets failure in the heart

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

The pathophysiology of mitochondrial cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

A mechanistic role for cardiac myocyte apoptosis in heart failure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Induction of autophagy and inhibition of tumorigenesis by beclin 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

RIP kinases initiate programmed necrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Detection of autophagy in cell death.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolic acidification during ischemia, and reduces ischemia/reperfusion injury

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890082

Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20360253

12 December 2020

inferred from PubMed ID database lookup

Necroptosis: a specialized pathway of programmed necrosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20360253

12 December 2020

inferred from PubMed ID database lookup

The bcl-2 gene product prevents programmed cell death of ventricular myocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20360253

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1161/CIRCRESAHA.109.212639

1 reference

30 July 2017

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30 July 2017

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