Limited importance of the dominant-negative effect of TP53 missense mutations (Q33931015)

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4 February 2020

title

Limited importance of the dominant-negative effect of TP53 missense mutations (English)

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Ewelina Stoczynska-Fidelus

4 February 2020

author

1

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4 February 2020

Michał Bieńkowski

4

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4 February 2020

Piotr Rieske

11

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4 February 2020

Dorota Jesionek-Kupnicka

8

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Dorota Jesionek-Kupnicka

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9

Radzislaw Kordek

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10

Pawel P Liberski

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4 February 2020

3

Sylwester Piaskowski

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4 February 2020

7

Izabela Zawlik

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author name string

Malgorzata Szybka

2

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4 February 2020

Krystyna Hulas-Bigoszewska

5

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4 February 2020

Mateusz Banaszczyk

6

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language of work or name

English

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publication date

13 June 2011

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4 February 2020

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volume

11

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page(s)

243

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https://scigraph.springernature.com/pub.10.1186/1471-2407-11-243

4 February 2020

exact match

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cites work

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Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

5 July 2018

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Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

5 July 2018

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5 July 2018

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Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes

5 July 2018

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Genetic and epigenetic alterations of tumor suppressor and tumor-related genes in gastric cancer

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Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerization of dimers. Implications on the dominant negative effect

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Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

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Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators

5 July 2018

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Inactivation of the p53 protein in cell lines derived from human esophageal cancers

5 July 2018

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Hemi- or homozygosity: a requirement for some but not other p53 mutant proteins to accumulate and exert a pathogenetic effect.

5 July 2018

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Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

5 July 2018

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12 December 2020

Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors

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12 December 2020

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Overview of RB gene mutations in patients with retinoblastoma. Implications for clinical genetic screening

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Identifiers

DOI

10.1186/1471-2407-11-243

1 reference

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Dimensions Publication ID

4 February 2020

0 references

1 reference

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4 February 2020

PubMed publication ID

21668955

1 reference