Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development (Q33929646)

30 July 2017

title

Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development (English)

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30 July 2017

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Adam Lacy-Hulbert

6

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Richard Hynes

7

object named as

Richard O Hynes

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30 July 2017

Arjan van der Flier

1

1 reference

30 July 2017

Kwabena Badu-Nkansah

2

1 reference

30 July 2017

Charles A Whittaker

3

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30 July 2017

Denise Crowley

4

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30 July 2017

Roderick T Bronson

5

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30 July 2017

language of work or name

English

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publication date

1 July 2010

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30 July 2017

number of pages

11

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inferred from page(s)

published in

Development

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30 July 2017

volume

137

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30 July 2017

issue

14

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30 July 2017

page(s)

2439-2449

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Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism

30 July 2017

cites work

1 reference

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Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis

5 July 2018

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alpha5beta1 Integrin blockade inhibits lymphangiogenesis in airway inflammation

5 July 2018

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5 July 2018

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Fibronectins in vascular morphogenesis

5 July 2018

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Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles

5 July 2018

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The role of integrin binding sites in fibronectin matrix assembly in vivo

5 July 2018

1 reference

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Cell-autonomous requirement for beta1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice

5 July 2018

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Increased expression of fibronectin and the alpha 5 beta 1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia

5 July 2018

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The developmental genetics of congenital heart disease.

5 July 2018

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A function blocking anti-mouse integrin alpha5beta1 antibody inhibits angiogenesis and impedes tumor growth in vivo

5 July 2018

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Endothelial expression of beta1 integrin is required for embryonic vascular patterning and postnatal vascular remodeling

5 July 2018

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Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature

5 July 2018

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Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins

5 July 2018

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Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice

5 July 2018

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Cell-matrix adhesion in vascular development

5 July 2018

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The RGD motif in fibronectin is essential for development but dispensable for fibril assembly

5 July 2018

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Sustained alterations in biodistribution of stem/progenitor cells in Tie2Cre+ alpha4(f/f) mice are hematopoietic cell autonomous

5 July 2018

1 reference

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Defective blood vessel development and pericyte/pvSMC distribution in alpha 4 integrin-deficient mouse embryos

5 July 2018

1 reference

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Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.

5 July 2018

1 reference

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Angiogenesis as a therapeutic target

5 July 2018

1 reference

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Vascular development of the brain requires beta8 integrin expression in the neuroepithelium

5 July 2018

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Integrin alpha(v)beta8-mediated activation of transforming growth factor-beta by perivascular astrocytes: an angiogenic control switch

5 July 2018

1 reference

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Integrin-linked kinase regulates endothelial cell survival and vascular development.

5 July 2018

1 reference

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The ins and outs of fibronectin matrix assembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Integrins: bidirectional, allosteric signaling machines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

5 July 2018

Fibronectin at a glance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

A reevaluation of integrins as regulators of angiogenesis

5 July 2018

1 reference

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Dual functions of [alpha]4[beta]1 integrin in epicardial development: initial migration and long-term attachment

5 July 2018

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Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits

5 July 2018

1 reference

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Function and interactions of integrins

5 July 2018

1 reference

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Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow

5 July 2018

1 reference

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Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

5 July 2018

1 reference

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Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1.

5 July 2018

1 reference

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Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin

5 July 2018

1 reference

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Normal development, wound healing, and adenovirus susceptibility in beta5-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Generalized lacZ expression with the ROSA26 Cre reporter strain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Dystrophic muscle in mice chimeric for expression of alpha5 integrin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Beta 1 integrin-dependent and -independent polymerization of fibronectin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Consequences of lack of beta 1 integrin gene expression in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Integrin beta1 subunit controls mural cell adhesion, spreading, and blood vessel wall stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Beta1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch.

29 October 2018

1 reference

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29 October 2018

Patent Ductus Arteriosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Overlapping and independent functions of fibronectin receptor integrins in early mesodermal development.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Formation of the atrioventricular septal structures in the normal mouse.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Fibronectin isoform distribution in the mouse. I. The alternatively spliced EIIIB, EIIIA, and V segments show widespread codistribution in the developing mouse embryo.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Expression of fibronectin, the integrin alpha 5, and alpha-smooth muscle actin in heart and lung development

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889609

Myocardial specificity for initiating endothelial-mesenchymal cell transition in embryonic chick heart correlates with a particulate distribution of fibronectin

29 October 2018

1 reference

12 December 2020

Patterns of fibronectin gene expression and splicing during cell migration in chicken embryos

1 reference

12 December 2020

A comparison of fibronectin, laminin, and galactosyltransferase adhesion mechanisms during embryonic cardiac mesenchymal cell migration in vitro

1 reference

12 December 2020

Effects of injecting fibronectin and antifibronectin antibodies on cushion mesenchyme formation in the chick. An in vivo study

1 reference

12 December 2020

Embryonic mesodermal defects in alpha 5 integrin-deficient mice

1 reference

12 December 2020

The fibronectin RGD motif is required for multiple angiogenic events during early embryonic development

1 reference

12 December 2020

Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death

1 reference

12 December 2020

A novel RGD-independent fibronectin assembly pathway initiated by alpha4beta1 integrin binding to the alternatively spliced V region

1 reference

12 December 2020

Reduced blood vessel formation and tumor growth in alpha5-integrin-negative teratocarcinomas and embryoid bodies

1 reference

12 December 2020

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

1 reference

12 December 2020

Central Roles of α 5 β 1 Integrin and Fibronectin in Vascular Development in Mouse Embryos and Embryoid Bodies

1 reference

12 December 2020

Gene transfer in utero biologically engineers a patent ductus arteriosus in lambs by arresting fibronectin-dependent neointimal formation

1 reference

12 December 2020

Heart development in fibronectin-null mice is governed by a genetic modifier on chromosome four

1 reference

12 December 2020

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