Probing the mechanism of inactivation of human pyruvate dehydrogenase by phosphorylation of three sites (Q33926252)

30 July 2017

Probing the mechanism of inactivation of human pyruvate dehydrogenase by phosphorylation of three sites (English)

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30 July 2017

1 reference

Korotchkina LG

1

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PubMed ID

11092882

30 July 2017

Patel MS

series ordinal

2

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PubMed ID

11092882

30 July 2017

language of work or name

English

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publication date

22 November 2000

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Journal of Biological Chemistry

30 July 2017

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30 July 2017

276

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30 July 2017

5731-5738

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30 July 2017

8

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Diversity of the pyruvate dehydrogenase kinase gene family in humans

30 July 2017

1 reference

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Cloning and characterization of PDK4 on 7q21.3 encoding a fourth pyruvate dehydrogenase kinase isoenzyme in human

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Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation

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Sites of phosphorylation on pyruvate dehydrogenase from bovine kidney and heart

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Mutagenesis studies of the phosphorylation sites of recombinant human pyruvate dehydrogenase. Site-specific regulation

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Occupancy of phosphorylation sites in pyruvate dehydrogenase phosphate complex in rat heart in vivo. Relation to proportion of inactive complex and rate of re-activation by phosphatase

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Pyruvate dehydrogenase kinase activity of pig heart pyruvate dehydrogenase (E1 component of pyruvate dehydrogenase complex).

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Marked differences between two isoforms of human pyruvate dehydrogenase kinase

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Binding of thiamin thiazolone pyrophosphate to mammalian pyruvate dehydrogenase and its effects on kinase and phosphatase activities

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The relationships between transketolase, yeast pyruvate decarboxylase and pyruvate dehydrogenase of the pyruvate dehydrogenase complex.

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Overexpression and characterization of human tetrameric pyruvate dehydrogenase and its individual subunits.

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Regulation of pig heart pyruvate dehydrogenase by phosphorylation. Studies on the subunit and phosphorylation stoicheiometries

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Function of the nonidentical subunits of mammalian pyruvate dehydrogenase

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The elementary reactions of the pig heart pyruvate dehydrogenase complex. A study of the inhibition by phosphorylation

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A general method for rapid site-directed mutagenesis using the polymerase chain reaction.

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Assembly and full functionality of recombinantly expressed dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complex

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Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex

21 January 2018

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Spectroscopic studies of the characterization of recombinant human dihydrolipoamide dehydrogenase and its site-directed mutants.

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Pyruvate dehydrogenase complex activity in normal and deficient fibroblasts

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Systemic deficiency of the first component of the pyruvate dehydrogenase complex.

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Regulation of heart muscle pyruvate dehydrogenase kinase

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Expression of pyruvate dehydrogenase isoforms during the aerobic/anaerobic transition in the development of the parasitic nematode Ascaris suum: altered stoichiometry of phosphorylation/inactivation.

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Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes

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Crystal structure of human branched-chain alpha-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease

21 January 2018

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Electrostatic and steric contributions to regulation at the active site of isocitrate dehydrogenase

21 January 2018

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Structural changes in glycogen phosphorylase induced by phosphorylation

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21 January 2018

Identifiers

DOI

10.1074/JBC.M007558200

1 reference

30 July 2017

1 reference

PubMed ID

11092882