Animal models in osteosarcoma (Q33917772)

30 July 2017

Animal models in osteosarcoma (English)

1 reference

Corrigendum: Animal models in osteosarcoma

30 July 2017

corrigendum / erratum

0 references

author name string

Maria V Guijarro

series ordinal

1

1 reference

30 July 2017

Steven C Ghivizzani

series ordinal

2

1 reference

30 July 2017

C Parker Gibbs

series ordinal

3

1 reference

30 July 2017

18 July 2014

1 reference

30 July 2017

Frontiers in Oncology

1 reference

30 July 2017

4

1 reference

30 July 2017

189

1 reference

Osteosarcoma treatment - where do we stand? A state of the art review.

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

A review of targeted therapies evaluated by the pediatric preclinical testing program for osteosarcoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Genome-wide association study identifies two susceptibility loci for osteosarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Genetically engineered mouse models and human osteosarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Osteosarcoma models: from cell lines to zebrafish

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Phase I/II trial and pharmacokinetic study of cixutumumab in pediatric patients with refractory solid tumors and Ewing sarcoma: a report from the Children's Oncology Group

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Phase II study of the mammalian target of rapamycin inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Of dogs and men: comparative biology as a tool for the discovery of novel biomarkers and drug development targets in osteosarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Targeted apc;twist double-mutant mice: a new model of spontaneous osteosarcoma that mimics the human disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Modeling human osteosarcoma in the mouse: From bedside to bench

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Rb regulates fate choice and lineage commitment in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Current concepts on the molecular biology of osteosarcoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Gene expression profiling of canine osteosarcoma reveals genes associated with short and long survival times.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly persons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Osteoblastic and osteolytic human osteosarcomas can be studied with a new xenograft mouse model producing spontaneous metastases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Maximizing mouse cancer models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Comparative biology of human and canine osteosarcoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Human xenograft osteosarcoma models with spontaneous metastasis in mice: clinical relevance and applicability for drug testing.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

The mighty mouse: genetically engineered mouse models in cancer drug development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Commonly used mouse models of osteosarcoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Identification of a novel germline MET mutation in dogs.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Genetically engineered models have advantages over xenografts for preclinical studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: osteosarcoma and related tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Lobaplatin as an adjuvant chemotherapy to surgery in canine appendicular osteosarcoma: a phase II evaluation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Metastasis-associated differences in gene expression in a murine model of osteosarcoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Inactivation of p53 and retinoblastoma family pathways in canine osteosarcoma cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Development of a novel spontaneous metastasis model of human osteosarcoma transplanted orthotopically into bone of athymic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Tumor spectrum analysis in p53-mutant mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Differential diagnosis of non-healing 'fungal'patches in horses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Treatment recommendations for osteosarcoma and adult soft tissue sarcomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Skeletal osteosarcoma. Animal model: canine osteosarcoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Frequency and structure of p53 rearrangements in human osteosarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Structural and functional correlations in parathyroid hormone responsive transplantable osteogenic sarcomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Alkaline phosphatase in serum and tumour of rats bearing a hormone-responsive transplantable osteogenic sarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. Dermatofibrosarcoma protuberans and giant cell fibroblastoma

5 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

Alterations of the p53, Rb and MDM2 genes in osteosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

Improved survival associated with postoperative wound infection in dogs treated with limb-salvage surgery for osteosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

TP53 gene mutations in canine osteosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

Functional hierarchy between two OSE2 elements in the control of osteocalcin gene expression in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

The pediatric preclinical testing program: description of models and early testing results.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

Tumor susceptibility of p21(Waf1/Cip1)-deficient mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

c-fos expression induces bone tumors in transgenic mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102850

Parathyroid hormone-responsive adenylate cyclase in induced transplantable osteogenic rat sarcoma

29 October 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2014.00189

Mutation spectrum of the retinoblastoma gene in osteosarcomas

21 January 2018

1 reference

12 December 2020

Expression of Cre recombinase in the developing mouse limb bud driven by aPrxl enhancer

1 reference

12 December 2020

A novel spontaneous metastasis model of human osteosarcoma developed using orthotopic transplantation of intact tumor tissue into tibia of nude mice

1 reference

12 December 2020

Studies on the development of radiation-induced bone tumours

1 reference

12 December 2020

Detection of c-fos expression in benign and malignant musculoskeletal lesions

1 reference

12 December 2020

Cytogenetic aberrations in osteosarcomas. Nonrandom deletions, rings, and double-minute chromosomes

1 reference

12 December 2020

Mutation of the p53 tumor suppressor gene in spontaneously occurring osteosarcomas of the dog

1 reference

12 December 2020

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

12 December 2020

Prognostic significance of a new histologic grading system for canine osteosarcoma

1 reference

12 December 2020

Growth hormone gene expression in canine normal growth plates and spontaneous osteosarcoma

1 reference

12 December 2020

Mutation spectrum of the p53 gene in bone and soft tissue sarcomas

1 reference

12 December 2020

Tumor suppressor PTEN is mutated in canine osteosarcoma cell lines and tumors

1 reference

12 December 2020

CDK4 gene amplification in osteosarcoma: reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons

1 reference

12 December 2020

Preclinical xenograft models of human sarcoma show nonrandom loss of aberrations

1 reference

12 December 2020

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

12 December 2020

Osteogenic sarcoma in children

1 reference

12 December 2020

P53 gene mutations in osteosarcomas in the dog

1 reference

12 December 2020

Alterations of the p15, p16,and p18 genes in osteosarcoma

1 reference

12 December 2020

Identifiers

DOI

10.3389/FONC.2014.00189

1 reference

30 July 2017

1 reference

30 July 2017

1 reference