Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension (Q33909537)

29 July 2017

Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension (English)

1 reference

29 July 2017

1 reference

1 reference

1 reference

Soni Savai Pullamsetti

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928992%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Karim C El Kasmi

1

1 reference

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8 June 2020

Steven C Pugliese

2

1 reference

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8 June 2020

Suzette R Riddle

3

1 reference

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8 June 2020

Jens M Poth

4

1 reference

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8 June 2020

Aimee L Anderson

5

1 reference

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8 June 2020

Maria G Frid

6

1 reference

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8 June 2020

Min Li

7

1 reference

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8 June 2020

Rajkumar Savai

9

1 reference

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8 June 2020

Maria A Nagel

10

1 reference

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8 June 2020

Mehdi A Fini

11

1 reference

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8 June 2020

Brian B Graham

12

1 reference

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8 June 2020

Rubin M Tuder

13

1 reference

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8 June 2020

Jacob E Friedman

14

1 reference

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8 June 2020

Holger K Eltzschig

15

1 reference

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8 June 2020

Ronald J Sokol

16

1 reference

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8 June 2020

Kurt R Stenmark

17

1 reference

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8 June 2020

language of work or name

English

0 references

publication date

13 June 2014

1 reference

29 July 2017

Journal of Immunology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928992%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

193

1 reference

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8 June 2020

issue

2

1 reference

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8 June 2020

page(s)

597-609

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Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

8 June 2020

cites work

1 reference

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Interleukin-6 signaling drives fibrosis in unresolved inflammation

5 July 2018

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Relevant issues in the pathology and pathobiology of pulmonary hypertension

5 July 2018

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MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts

5 July 2018

1 reference

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STAT3 signaling in pulmonary arterial hypertension

5 July 2018

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Protective role of IL-6 in vascular remodeling in Schistosoma pulmonary hypertension

5 July 2018

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The adventitia: Essential role in pulmonary vascular remodeling

5 July 2018

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Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension

5 July 2018

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Role of arginase 1 from myeloid cells in th2-dominated lung inflammation.

5 July 2018

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Local arginase 1 activity is required for cutaneous wound healing

5 July 2018

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The adventitia: essential regulator of vascular wall structure and function

5 July 2018

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C/EBP transcription factors mediate epicardial activation during heart development and injury.

5 July 2018

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Host responses in tissue repair and fibrosis

5 July 2018

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CCAAT/enhancer-binding protein β (C/EBPβ) expression regulates dietary-induced inflammation in macrophages and adipose tissue in mice

5 July 2018

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The role of tocilizumab in the management of rheumatoid arthritis

5 July 2018

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Hypoxia induces unique proliferative response in adventitial fibroblasts by activating PDGFβ receptor-JNK1 signalling

5 July 2018

1 reference

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Modern age pathology of pulmonary arterial hypertension

5 July 2018

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Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension

5 July 2018

1 reference

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Protective and pathogenic functions of macrophage subsets

5 July 2018

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Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1

5 July 2018

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Oxygen sensing, homeostasis, and disease

5 July 2018

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Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension

5 July 2018

1 reference

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Early macrophage recruitment and alternative activation are critical for the later development of hypoxia-induced pulmonary hypertension.

5 July 2018

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Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension.

5 July 2018

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Arginine usage in mycobacteria-infected macrophages depends on autocrine-paracrine cytokine signaling

5 July 2018

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Macrophages: master regulators of inflammation and fibrosis

5 July 2018

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Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasis

5 July 2018

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Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype.

5 July 2018

1 reference

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Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia

5 July 2018

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A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

5 July 2018

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Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.

5 July 2018

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Macrophages are alternatively activated in patients with endometriosis and required for growth and vascularization of lesions in a mouse model of disease

5 July 2018

1 reference

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Inflammation, growth factors, and pulmonary vascular remodeling

5 July 2018

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Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension

5 July 2018

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Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice

5 July 2018

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Interleukin-6 overexpression induces pulmonary hypertension

5 July 2018

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Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

5 July 2018

1 reference

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Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage

5 July 2018

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Vascular endothelial growth factor in the lung

5 July 2018

1 reference

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Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways

5 July 2018

1 reference

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Induction of arginase I transcription by IL-4 requires a composite DNA response element for STAT6 and C/EBPbeta

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100597

STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells

5 July 2018

1 reference

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Stat1-independent induction of SOCS-3 by interferon-gamma is mediated by sustained activation of Stat3 in mouse embryonic fibroblasts.

5 July 2018

1 reference

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Fibrotic disease and the T(H)1/T(H)2 paradigm

5 July 2018

1 reference

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Enhancer-mediated control of macrophage-specific arginase I expression

5 July 2018

1 reference

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The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100597

SOCS3 regulates the plasticity of gp130 signaling

5 July 2018

1 reference

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Alternative activation of macrophages

5 July 2018

1 reference

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Mutational switch of an IL-6 response to an interferon-gamma-like response

5 July 2018

1 reference

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Roles of STAT3 defined by tissue-specific gene targeting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100597

Pulmonary hypertension and inflammation.

5 July 2018

1 reference

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

5 July 2018

1 reference

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Immune and inflammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension.

5 July 2018

1 reference

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Soluble CD163 in young sickle cell disease patients and their trait siblings: a biomarker for pulmonary hypertension and vaso-occlusive complications

29 October 2018

1 reference

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Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change

29 October 2018

1 reference

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Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension.

29 October 2018

1 reference

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Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension

29 October 2018

1 reference

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Alternatively activated macrophages (M2 macrophages) in the skin of patient with localized scleroderma.

29 October 2018

1 reference

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General nature of the STAT3-activated anti-inflammatory response.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100597

Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100597

Increased interleukin-1 and interleukin-6 serum concentrations in severe primary pulmonary hypertension.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100597

Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension

29 October 2018

1 reference

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Up-regulation of human monocyte CD163 upon activation of cell-surface Toll-like receptors

29 October 2018

1 reference

12 December 2020

Pathology of pulmonary hypertension

1 reference

12 December 2020

Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKCzeta in the pulmonary artery adventitia

1 reference

12 December 2020

Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) increases lung inflammation and activates pulmonary microvascular endothelial cells via an IL-4-dependent mechanism

1 reference

12 December 2020

Attenuated liver fibrosis and depressed serum albumin levels in carbon tetrachloride-treated IL-6-deficient mice

1 reference

12 December 2020

Serum levels of soluble CD163 in patients with systemic sclerosis

1 reference

12 December 2020

Inflammation in Pulmonary Arterial Hypertension

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12 December 2020

Association of interleukin 6 release from endothelial cells and pulmonary hypertension in SLE

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12 December 2020

Identification of alternatively activated macrophages in new-onset paediatric and adult immunoglobulin A nephropathy: potential role in mesangial matrix expansion

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1303048

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928992%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928992%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference