mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning (Q33908562)

29 July 2017

mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning (English)

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29 July 2017

11

Craig W Lindsley

1 reference

29 July 2017

13

P Jeffrey Conn

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29 July 2017

8

Zixiu Xiang

1 reference

29 July 2017

4

Douglas J Sheffler

1 reference

29 July 2017

12

M Foster Olive

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29 July 2017

10

Paulianda J Jones

1 reference

29 July 2017

1

Jennifer E Ayala

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29 July 2017

3

Jessica L Banko

1 reference

29 July 2017

Yelin Chen

2

1 reference

29 July 2017

Richard Williams

5

1 reference

29 July 2017

Alexandra N Telk

6

1 reference

29 July 2017

Noreen L Watson

7

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29 July 2017

Yongqin Zhang

9

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29 July 2017

language of work or name

English

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publication date

18 March 2009

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29 July 2017

Neuropsychopharmacology

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29 July 2017

34

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29 July 2017

2057-2071

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29 July 2017

9

1 reference

https://scigraph.springernature.com/pub.10.1038/npp.2009.30

29 July 2017

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Allosteric potentiators of metabotropic glutamate receptor subtype 5 have differential effects on different signaling pathways in cortical astrocytes

5 July 2018

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The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity

5 July 2018

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A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models

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5 July 2018

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5 July 2018

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Rap1-induced p38 mitogen-activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex. Potential role in (S)-3,5-dihydroxyphenylglycene-induced long term depression

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus.

5 July 2018

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5 July 2018

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Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

5 July 2018

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Pharmacology and functions of metabotropic glutamate receptors

5 July 2018

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5 July 2018

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Theta pattern stimulation and the induction of LTP: the sequence in which synapses are stimulated determines the degree to which they potentiate

5 July 2018

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Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

5 July 2018

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5 July 2018

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Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory.

21 January 2018

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Regulation of eukaryotic initiation factor 4E by converging signaling pathways during metabotropic glutamate receptor-dependent long-term depression.

21 January 2018

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Cell-specific extracellular signal-regulated kinase activation by multiple G protein-coupled receptor families in hippocampus

21 January 2018

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21 January 2018

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Effect of antipsychotic treatment on the prepulse inhibition deficit of mGluR5 knockout mice

21 January 2018

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Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors

21 January 2018

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The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates PCP-induced cognitive deficits in rats

21 January 2018

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Attenuation of ketamine-evoked behavioral responses by mGluR5 positive modulators in mice.

21 January 2018

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Acute stress facilitates hippocampal CA1 metabotropic glutamate receptor-dependent long-term depression.

21 January 2018

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Local facilitation of hippocampal metabotropic glutamate receptor-dependent long-term depression by corticosterone and dexamethasone

21 January 2018

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Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1.

21 January 2018

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The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity

21 January 2018

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Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release

21 January 2018

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Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

21 January 2018

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Sustained activation of metabotropic glutamate receptor 5 and protein tyrosine phosphatases mediate the expression of (S)-3,5-dihydroxyphenylglycine-induced long-term depression in the hippocampal CA1 region

21 January 2018

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21 January 2018

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Induction of LTD in the adult hippocampus by the synaptic activation of AMPA/kainate and metabotropic glutamate receptors.

21 January 2018

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Different forms of LTD in the CA1 region of the hippocampus: role of age and stimulus protocol.

21 January 2018

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Inhibition of group I metabotropic glutamate receptor responses in vivo in rats by a new generation of carboxyphenylglycine-like amino acid antagonists

21 January 2018

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21 January 2018

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Shift in induction mechanisms underlies an age-dependent increase in DHPG-induced synaptic depression at CA3 CA1 synapses

21 January 2018

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21 January 2018

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21 January 2018

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Metabotropic glutamate receptor 1 (mGluR1) and 5 (mGluR5) regulate late phases of LTP and LTD in the hippocampal CA1 region in vitro

21 January 2018

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Developmental switch in synaptic mechanisms of hippocampal metabotropic glutamate receptor-dependent long-term depression.

21 January 2018

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Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome

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Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function.

21 January 2018

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Differential regulation of metabotropic glutamate receptor 5-mediated phosphoinositide hydrolysis and extracellular signal-regulated kinase responses by protein kinase C in cultured astrocytes

21 January 2018

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(S)-4-carboxy-3-hydroxyphenylglycine activates phosphatidyl inositol linked metabotropic glutamate receptors in different brain regions of the neonatal rat.

21 January 2018

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Kinase suppressor of Ras1 compartmentalizes hippocampal signal transduction and subserves synaptic plasticity and memory formation.

21 January 2018

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The mechanism of presynaptic long-term depression mediated by group I metabotropic glutamate receptors

21 January 2018

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Differential roles for group 1 mGluR subtypes in induction and expression of chemically induced hippocampal long-term depression

21 January 2018

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Group I mGluR-induced epileptogenesis: distinct and overlapping roles of mGluR1 and mGluR5 and implications for antiepileptic drug design

21 January 2018

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Two distinct signaling pathways upregulate NMDA receptor responses via two distinct metabotropic glutamate receptor subtypes.

21 January 2018

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Modulation of presynaptic calcium transients by metabotropic glutamate receptor activation: a differential role in acute depression of synaptic transmission and long-term depression.

29 October 2018

1 reference

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Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor.

29 October 2018

1 reference

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Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1.

29 October 2018

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DHPG-induced LTD in area CA1 of juvenile rat hippocampus; characterisation and sensitivity to novel mGlu receptor antagonists

29 October 2018

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12 December 2020

Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term Depression

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12 December 2020

Metabotropic glutamate receptors trigger homosynaptic protein synthesis to prolong long-term potentiation

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12 December 2020

Induction of LTD by activation of group I mGluR in the dentate gyrus in vitro

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12 December 2020

(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

1 reference

12 December 2020

Long-term potentiation in the hippocampus of fragile X knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2009.30

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NPP.2009.30

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference