The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage (Q33903185)

29 July 2017

The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage (English)

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29 July 2017

M Tortorella

1

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29 July 2017

M Pratta

2

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29 July 2017

R Q Liu

3

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29 July 2017

I Abbaszade

4

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29 July 2017

H Ross

5

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29 July 2017

T Burn

6

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29 July 2017

E Arner

7

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29 July 2017

language of work or name

English

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publication date

1 August 2000

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Journal of Biological Chemistry

29 July 2017

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29 July 2017

275

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29 July 2017

25791-25797

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29 July 2017

33

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Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

29 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

The exon/intron organization and chromosomal mapping of the mouse ADAMTS-1 gene encoding an ADAM family protein with TSP motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

cDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Evolutionary families of metallopeptidases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M001065200

ADAMs in fertilization and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Extended and globular protein domains in cartilage proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Mechanism of catabolism of aggrecan by articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Cell-mediated catabolism of aggrecan. Evidence that cleavage at the "aggrecanase" site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Cytokine-induced cartilage proteoglycan degradation is mediated by aggrecanase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Cell adhesion to a motif shared by the malaria circumsporozoite protein and thrombospondin is mediated by its glycosaminoglycan-binding region and not by CSVTCG

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

ADAMTS-1 protein anchors at the extracellular matrix through the thrombospondin type I motifs and its spacing region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Methotrexate, a high-affinity pseudosubstrate of dihydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Degradation of cartilage aggrecan by collagenase-3 (MMP-13)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Cleavage of native cartilage aggrecan by neutrophil collagenase (MMP-8) is distinct from endogenous cleavage by aggrecanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Identification of aggrecanase activity in medium of cartilage culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Interactions of pentosan polysulfate with cartilage matrix proteins and synovial fibroblasts derived from patients with osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

Cartilage oligomeric matrix protein and thrombospondin 1. Purification from articular cartilage, electron microscopic structure, and chondrocyte binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001065200

21 January 2018

Identifiers

DOI

10.1074/JBC.M001065200

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29 July 2017

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